(Q34416391)

2 August 2017

title

A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma (English)

1 reference

2 August 2017

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John D Lambris

14

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Marsha Wills-Karp

15

object named as

Marsha Wills-Karp

1 reference

2 August 2017

Jörg Köhl

1

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2 August 2017

Ralf Baelder

2

1 reference

2 August 2017

Ian P Lewkowich

3

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2 August 2017

Manoj K Pandey

4

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2 August 2017

Heiko Hawlisch

5

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2 August 2017

Lihua Wang

6

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2 August 2017

Jennifer Best

7

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2 August 2017

Nancy S Herman

8

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2 August 2017

Alyssa A Sproles

9

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2 August 2017

Jörg Zwirner

10

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2 August 2017

Jeffrey A Whitsett

11

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2 August 2017

Craig Gerard

12

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2 August 2017

Georgia Sfyroera

13

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2 August 2017

language of work or name

English

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publication date

1 March 2006

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Journal of Clinical Investigation

2 August 2017

published in

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2 August 2017

volume

116

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2 August 2017

issue

3

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2 August 2017

page(s)

783-796

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Complement and Toll-like receptors: key regulators of adaptive immune responses

2 August 2017

cites work

1 reference

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Role of C5 in the development of airway inflammation, airway hyperresponsiveness, and ongoing airway response

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In vivo depletion of lung CD11c+ dendritic cells during allergen challenge abrogates the characteristic features of asthma

6 July 2018

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Role of C5a in inflammatory responses

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The complement inhibitory protein DAF (CD55) suppresses T cell immunity in vivo

6 July 2018

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Plasmacytoid dendritic cells in immunity

6 July 2018

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The anaphylatoxins bridge innate and adaptive immune responses in allergic asthma.

6 July 2018

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Time to draw breath: asthma-susceptibility genes are identified

6 July 2018

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6 July 2018

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C5a mutants are potent antagonists of the C5a receptor (CD88) and of C5L2: position 69 is the locus that determines agonism or antagonism

6 July 2018

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Influenza virus-induced dendritic cell maturation is associated with the induction of strong T cell immunity to a coadministered, normally nonimmunogenic protein

6 July 2018

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6 July 2018

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6 July 2018

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Complement factor 3 mediates particulate matter-induced airway hyperresponsiveness

6 July 2018

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6 July 2018

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Expression of the complement anaphylatoxin C3a and C5a receptors on bronchial epithelial and smooth muscle cells in models of sepsis and asthma

6 July 2018

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Cutting edge: guinea pigs with a natural C3a-receptor defect exhibit decreased bronchoconstriction in allergic airway disease: evidence for an involvement of the C3a anaphylatoxin in the pathogenesis of asthma

6 July 2018

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Myeloid dendritic cells induce Th2 responses to inhaled antigen, leading to eosinophilic airway inflammation

6 July 2018

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CC chemokine receptor (CCR)3/eotaxin is followed by CCR4/monocyte-derived chemokine in mediating pulmonary T helper lymphocyte type 2 recruitment after serial antigen challenge in vivo

6 July 2018

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Selection of a C5a receptor antagonist from phage libraries attenuating the inflammatory response in immune complex disease and ischemia/reperfusion injury.

6 July 2018

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Immunologic basis of antigen-induced airway hyperresponsiveness

6 July 2018

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Interleukin-13: central mediator of allergic asthma

6 July 2018

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The C5a chemoattractant receptor mediates mucosal defence to infection

6 July 2018

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Interleukin-4 augments production of the third complement component by the alveolar epithelial cell line A549.

6 July 2018

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Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice

6 July 2018

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Pulmonary injury induced by C3a and C5a anaphylatoxins

6 July 2018

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Release of leukotrienes from guinea pig lung stimulated by C5ades Arg anaphylatoxin

6 July 2018

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The role of the complement system in the pathogenesis of multiple organ failure in shock

6 July 2018

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C5a negatively regulates toll-like receptor 4-induced immune responses

6 July 2018

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Intranasal exposure of mice to house dust mite elicits allergic airway inflammation via a GM-CSF-mediated mechanism

27 October 2018

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Complement C5a receptor is essential for the optimal generation of antiviral CD8+ T cell responses

27 October 2018

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Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen

27 October 2018

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Influenza and asthma: adding to the respiratory burden

27 October 2018

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Complement factor C5a mediates renal ischemia-reperfusion injury independent from neutrophils.

27 October 2018

1 reference

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Absence of the complement anaphylatoxin C3a receptor suppresses Th2 effector functions in a murine model of pulmonary allergy.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1386108

Conditional gene expression in the respiratory epithelium of the mouse.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1386108

Complement factors C3a and C5a are increased in bronchoalveolar lavage fluid after segmental allergen provocation in subjects with asthma

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1386108

Contribution of anaphylatoxin C5a to late airway responses after repeated exposure of antigen to allergic rats.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1386108

Enhanced expression of complement C5a receptor mRNA in human diseased kidney assessed by in situ hybridization

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1386108

Resistance to antigen-induced airway hyperresponsiveness requires endogenous production of IL-12.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1386108

TLR9-Dependent Recognition of MCMV by IPC and DC Generates Coordinated Cytokine Responses that Activate Antiviral NK Cell Function

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1386108

Cutting edge: differential chemokine production by myeloid and plasmacytoid dendritic cells

27 October 2018

1 reference

12 December 2020

Differences in circulating dendritic cell subtypes in cord blood and peripheral blood of healthy and allergic children

1 reference

12 December 2020

Characterization of C5aR expression on murine myeloid and lymphoid cells by the use of a novel monoclonal antibody

1 reference

12 December 2020

C5a initiates the inflammatory cascade in immune complex peritonitis

1 reference

12 December 2020

Inflammatory Effects of Endotoxin-Like Contaminants in Commonly Used Protein Preparations

1 reference

12 December 2020

Anaphylatoxin-mediated contraction of guinea pig lung strips: a nonhistamine tissue response

1 reference

12 December 2020

Regulation of IgE responses to inhaled antigen in mice by antigen-specific gamma delta T cells

1 reference

12 December 2020

A genome-wide search for asthma susceptibility loci in ethnically diverse populations. The Collaborative Study on the Genetics of Asthma (CSGA)

1 reference

12 December 2020

Generation of anaphylatoxins through proteolytic processing of C3 and C5 by house dust mite protease

1 reference

12 December 2020

A Genome-wide Search for Linkage to Asthma22See the Appendix

1 reference

12 December 2020

Ablation of the SERCA3 gene alters epithelium-dependent relaxation in mouse tracheal smooth muscle.

1 reference

12 December 2020

Variations in the C3, C3a receptor, and C5 genes affect susceptibility to bronchial asthma

1 reference

12 December 2020

Requirements for C5a receptor-mediated IL-4 and IL-13 production and leukotriene C4 generation in human basophils

1 reference

12 December 2020

A role for the C3a anaphylatoxin receptor in the effector phase of asthma

1 reference

12 December 2020

Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma

1 reference

12 December 2020

Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen

1 reference

12 December 2020

Cutting edge: the absence of C3 demonstrates a role for complement in Th2 effector functions in a murine model of pulmonary allergy

1 reference

12 December 2020

Pharmacological targeting of anaphylatoxin receptors during the effector phase of allergic asthma suppresses airway hyperresponsiveness and airway inflammation

1 reference

12 December 2020

Dynamics of Dendritic Cell Phenotype and Interactions with CD4+ T Cells in Airway Inflammation and Tolerance

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI26582

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2 August 2017

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2 August 2017

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