(Q36335907)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26551681%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Platelet-derived HMGB1 is a critical mediator of thrombosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26551681%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

0 references

1

1 reference

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29 February 2020

Johannes Rheinlaender

6

1 reference

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29 February 2020

Tilman E. Schäffer

7

1 reference

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29 February 2020

Julia-Stefanie Frick

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26551681%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

4

Susanne Feil

1 reference

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29 February 2020

Simon C Watkins

18

1 reference

ORCID Public Data File 2021

Oliver Borst

10

object named as

Oliver Borst

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26551681%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

24

Meinrad Gawaz

1 reference

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29 February 2020

23

Michael T Lotze

1 reference

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29 February 2020

author name string

Rebecca Bodenstein

2

1 reference

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29 February 2020

Qiwei Chen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26551681%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Robert Feil

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26551681%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Erwin Bohn

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26551681%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Patrick Münzer

11

1 reference

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29 February 2020

Britta Walker

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26551681%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Justin Markel

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26551681%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Gabor Csanyi

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26551681%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Patrick J Pagano

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26551681%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Patricia Loughran

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26551681%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Morgan E Jessup

17

1 reference

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29 February 2020

Grant C Bullock

19

1 reference

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29 February 2020

Jason L Sperry

20

1 reference

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29 February 2020

Brian S Zuckerbraun

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26551681%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Timothy R Billiar

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26551681%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Matthew D Neal

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26551681%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

language of work or name

English

0 references

publication date

9 November 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26551681%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

29 February 2020

published in

1 reference

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29 February 2020

volume

125

1 reference

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29 February 2020

issue

12

1 reference

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29 February 2020

page(s)

4638-4654

1 reference

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describes a project that uses

29 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4665785/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation.

30 September 2017

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Necrotic cell-derived high mobility group box 1 attracts antigen-presenting cells but inhibits hepatocyte growth factor-mediated tropism of mesenchymal stem cells for apoptotic cell death.

30 September 2017

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Extracellular cyclophilin A activates platelets via EMMPRIN (CD147) and PI3K/Akt signaling, which promotes platelet adhesion and thrombus formation in vitro and in vivo.

30 September 2017

1 reference

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Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation

30 September 2017

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Toll-like receptor 4 regulates platelet function and contributes to coagulation abnormality and organ injury in hemorrhagic shock and resuscitation

30 September 2017

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Emerging roles for platelets as immune and inflammatory cells

30 September 2017

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Activated platelets interfere with recruitment of mesenchymal stem cells to apoptotic cardiac cells via high mobility group box 1/Toll-like receptor 4-mediated down-regulation of hepatocyte growth factor receptor MET

30 September 2017

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Prehospital use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with a reduced incidence of trauma-induced coagulopathy

30 September 2017

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Hepatocyte-specific high-mobility group box 1 deletion worsens the injury in liver ischemia/reperfusion: a role for intracellular high-mobility group box 1 in cellular protection

30 September 2017

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Intracellular Hmgb1 inhibits inflammatory nucleosome release and limits acute pancreatitis in mice

30 September 2017

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Conditional ablation of HMGB1 in mice reveals its protective function against endotoxemia and bacterial infection

30 September 2017

1 reference

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Role of multiligand/RAGE axis in platelet activation.

30 September 2017

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Platelets in tissue repair: control of apoptosis and interactions with regenerative cells

30 September 2017

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Endothelial TLR4 activation impairs intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS-NO-nitrite signaling

30 September 2017

1 reference

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Circulating histones are mediators of trauma-associated lung injury.

30 September 2017

1 reference

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HMGB1 and leukocyte migration during trauma and sterile inflammation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4665785

Platelet-derived Toll-like receptor 4 (Tlr-4) is sufficient to promote microvascular thrombosis in endotoxemia.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4665785

Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury

30 September 2017

1 reference

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Differential dynamics of platelet contact and spreading

30 September 2017

1 reference

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Arterial thrombosis--insidious, unpredictable and deadly

30 September 2017

1 reference

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Biphasic roles for soluble guanylyl cyclase (sGC) in platelet activation

30 September 2017

1 reference

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Pseudofracture: an acute peripheral tissue trauma model

30 September 2017

1 reference

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Platelets, inflammation and tissue regeneration

30 September 2017

1 reference

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DNA attenuates enterocyte Toll-like receptor 4-mediated intestinal mucosal injury after remote trauma

30 September 2017

1 reference

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HMGB1 is a therapeutic target for sterile inflammation and infection

30 September 2017

1 reference

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Extracellular DNA traps promote thrombosis.

30 September 2017

1 reference

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Systemic inflammation and liver injury following hemorrhagic shock and peripheral tissue trauma involve functional TLR9 signaling on bone marrow-derived cells and parenchymal cells.

30 September 2017

1 reference

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Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/MyD88 and the cGMP-dependent protein kinase pathway

30 September 2017

1 reference

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Platelets in inflammation and atherogenesis.

30 September 2017

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High mobility group box 1 protein interacts with multiple Toll-like receptors

30 September 2017

1 reference

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Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-alpha production in vivo

30 September 2017

1 reference

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The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion

30 September 2017

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Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein

30 September 2017

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Cyclic GMP-dependent protein kinases and the cardiovascular system: insights from genetically modified mice.

30 September 2017

1 reference

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Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells

30 September 2017

1 reference

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Platelets in atherothrombosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4665785

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4665785

Disseminated intravascular coagulation in trauma patients

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4665785

Highly specific, membrane-permeant peptide blockers of cGMP-dependent protein kinase Ialpha inhibit NO-induced cerebral dilation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4665785

HMG-1 as a late mediator of endotoxin lethality in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4665785

The vasodilator-stimulated phosphoprotein (VASP) is involved in cGMP- and cAMP-mediated inhibition of agonist-induced platelet aggregation, but is dispensable for smooth muscle function.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4665785

Reduced microvascular thrombosis and improved outcome in acute murine stroke by inhibiting GP IIb/IIIa receptor-mediated platelet aggregation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4665785

Rescue of cGMP kinase I knockout mice by smooth muscle specific expression of either isozyme

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4665785

A stimulatory role for cGMP-dependent protein kinase in platelet activation

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4665785

HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4665785

Macrophage migration inhibitory factor limits activation-induced apoptosis of platelets via CXCR7-dependent Akt signaling.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4665785

Activated platelets present high mobility group box 1 to neutrophils, inducing autophagy and promoting the extrusion of neutrophil extracellular traps.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4665785

Benzyl alcohol attenuates acetaminophen-induced acute liver injury in a Toll-like receptor-4-dependent pattern in mice.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4665785

Intracellular cyclophilin A is an important Ca(2+) regulator in platelets and critically involved in arterial thrombus formation.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4665785

Role of high-mobility group box 1 protein in post-infarction healing process and left ventricular remodelling

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4665785

Elevated high-mobility group box 1 levels in patients with cerebral and myocardial ischemia.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4665785

A platelet secretion pathway mediated by cGMP-dependent protein kinase

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4665785

A mitogen-activated protein kinase-dependent signaling pathway in the activation of platelet integrin alpha IIbbeta3.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4665785

Increased adhesion and aggregation of platelets lacking cyclic guanosine 3',5'-monophosphate kinase I.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4665785

Circulating platelets as a source of the damage-associated molecular pattern HMGB1 in patients with systemic sclerosis

22 September 2018

1 reference

12 December 2020

Occurrence of amphoterin (HMG1) as an endogenous protein of human platelets that is exported to the cell surface upon platelet activation

1 reference

12 December 2020

Imaging the elastic modulus of human platelets during thrombin-induced activation using scanning ion conductance microscopy

1 reference

12 December 2020

Elevated mitochondrial membrane potential of circulating monocyte-platelet aggregates in patients with coronary heart disease

1 reference

12 December 2020

Plasma concentrations and importance of High Mobility Group Box protein in the prognosis of organ failure in patients with disseminated intravascular coagulation

1 reference

12 December 2020

High-mobility group box 1 protein promotes development of microvascular thrombosis in rats

1 reference

12 December 2020

Pf4-Cre transgenic mice allow the generation of lineage-restricted gene knockouts for studying megakaryocyte and platelet function in vivo

1 reference

12 December 2020

Hemorrhagic shock induces NAD(P)H oxidase activation in neutrophils: role of HMGB1-TLR4 signaling

1 reference

12 December 2020

Systemic inflammation and remote organ injury following trauma require HMGB1

1 reference

12 December 2020

IL-6 and maturation govern TLR2 and TLR4 induced TLR agonist tolerance and cross-tolerance in dendritic cells

1 reference

12 December 2020

High-Mobility Group Box-1 in Ischemia-Reperfusion Injury of the Heart

1 reference

12 December 2020

The correlation between platelet activation markers and HMGB1 in patients with disseminated intravascular coagulation and hematologic malignancy

1 reference

12 December 2020

Introduction: HMGB1 in inflammation and innate immunity

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI81660

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26551681%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26551681%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference