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Role of group A p21-activated kinases in the anti-apoptotic activity of the pseudorabies virus US3 protein kinase.
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Europe PubMed Central
PMC publication ID
3477636
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21093504%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
title
Role of group A p21-activated kinases in the anti-apoptotic activity of the pseudorabies virus US3 protein kinase
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3477636
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21093504%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
main subject
apoptotic process
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author
Jonathan Chernoff
series ordinal
4
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Europe PubMed Central
PMC publication ID
3477636
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21093504%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
Herman W. Favoreel
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5
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Europe PubMed Central
PMC publication ID
3477636
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21093504%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
author name string
C Van den Broeke
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1
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Europe PubMed Central
PMC publication ID
3477636
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21093504%20AND%20SRC:MED&resulttype=core&format=json
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16 January 2020
M Radu
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2
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Europe PubMed Central
PMC publication ID
3477636
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21093504%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
H J Nauwynck
series ordinal
3
1 reference
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Europe PubMed Central
PMC publication ID
3477636
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21093504%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
publication date
18 November 2010
1 reference
stated in
Europe PubMed Central
PMC publication ID
3477636
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21093504%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
published in
Virus Research
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Europe PubMed Central
PMC publication ID
3477636
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21093504%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
volume
155
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Europe PubMed Central
PMC publication ID
3477636
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21093504%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
issue
1
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stated in
Europe PubMed Central
PMC publication ID
3477636
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21093504%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
page(s)
376-380
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Europe PubMed Central
PMC publication ID
3477636
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21093504%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
cites work
Point mutations in BHV-1 Us3 gene abolish its ability to induce cytoskeletal changes in various cell types.
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PubMed Central
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An emerging role for p21-activated kinases (Paks) in viral infections
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Pseudorabies virus US3-mediated inhibition of apoptosis does not affect infectious virus production
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PubMed Central
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Group I p21-activated kinases: emerging roles in immune function and viral pathogenesis
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PAK1 and PAK2 have different roles in HGF-induced morphological responses
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PubMed Central
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Alphaherpesvirus US3-mediated reorganization of the actin cytoskeleton is mediated by group A p21-activated kinases
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The kinase activity of pseudorabies virus US3 is required for modulation of the actin cytoskeleton
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30 September 2017
An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase
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30 September 2017
Pak1 and Pak2 mediate tumor cell invasion through distinct signaling mechanisms
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In transduced cells, the US3 protein kinase of herpes simplex virus 1 precludes activation and induction of apoptosis by transfected procaspase 3.
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30 September 2017
A point mutation in the putative ATP binding site of the pseudorabies virus US3 protein kinase prevents Bad phosphorylation and cell survival following apoptosis induction
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PubMed Central
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30 September 2017
Cytoskeletal rearrangements and cell extensions induced by the US3 kinase of an alphaherpesvirus are associated with enhanced spread
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The protein encoded by the US3 orthologue of Marek's disease virus is required for efficient de-envelopment of perinuclear virions and involved in actin stress fiber breakdown
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Herpes simplex virus protein kinase US3 activates and functionally overlaps protein kinase A to block apoptosis
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30 September 2017
The HSV-1 Us3 protein kinase is sufficient to block apoptosis induced by overexpression of a variety of Bcl-2 family members.
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PubMed Central
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30 September 2017
Herpes simplex virus type 1 primary envelopment: UL34 protein modification and the US3-UL34 catalytic relationship
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30 September 2017
Pseudorabies virus US3 protein kinase mediates actin stress fiber breakdown
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30 September 2017
Ultrastructural localization of the herpes simplex virus type 1 UL31, UL34, and US3 proteins suggests specific roles in primary envelopment and egress of nucleocapsids
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30 September 2017
HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals
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PubMed Central
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The US3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the absence of other viral proteins
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30 September 2017
p21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosis
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PubMed Central
reference URL
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30 September 2017
Proteolytic cleavage and activation of PAK2 during UV irradiation-induced apoptosis in A431 cells
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PubMed Central
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30 September 2017
The herpes simplex virus 1 protein kinase US3 is required for protection from apoptosis induced by the virus
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477636
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Identification of proteins phosphorylated directly by the Us3 protein kinase encoded by herpes simplex virus 1
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29 June 2018
p21-activated protein kinase gamma-PAK suppresses programmed cell death of BALB3T3 fibroblasts
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reference URL
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Analysis of filamentous process induction and nuclear localization properties of the HSV-2 serine/threonine kinase Us3.
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PubMed Central
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22 September 2018
The pseudorabies virus US3 protein kinase possesses anti-apoptotic activity that protects cells from apoptosis during infection and after treatment with sorbitol or staurosporine
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PubMed Central
reference URL
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22 September 2018
The Us3 protein kinase of herpes simplex virus 1 blocks apoptosis and induces phosporylation of the Bcl-2 family member Bad.
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PubMed Central
reference URL
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22 September 2018
The herpes simplex virus-1 Us3 protein kinase blocks CD8T cell lysis by preventing the cleavage of Bid by granzyme B.
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PubMed Central
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22 September 2018
Effect of the pseudorabies virus US3 protein on nuclear membrane localization of the UL34 protein and virus egress from the nucleus
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477636
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22 September 2018
Heat shock stress induces cleavage and activation of PAK2 in apoptotic cells
1 reference
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reference URL
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22 September 2018
The US3-encoded protein kinase from pseudorabies virus affects egress of virions from the nucleus
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477636
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22 September 2018
Effect of specific antibodies on the cell-associated spread of pseudorabies virus in monolayers of different cell types
1 reference
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22 September 2018
Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.11.003
retrieved
7 January 2021
Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2010.11.003
retrieved
7 January 2021
Identifiers
DOI
10.1016/J.VIRUSRES.2010.11.003
1 reference
stated in
Europe PubMed Central
PMC publication ID
3477636
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21093504%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
PMC publication ID
3477636
1 reference
stated in
Europe PubMed Central
PMC publication ID
3477636
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21093504%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
PubMed publication ID
21093504
1 reference
stated in
Europe PubMed Central
PMC publication ID
3477636
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21093504%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
ResearchGate publication ID
49624746
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