(Q28270326)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20071173%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

review article

1 reference

title

An emerging role for p21-activated kinases (Paks) in viral infections (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20071173%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20071173%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Herman W. Favoreel

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20071173%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

author name string

Celine Van den Broeke

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20071173%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Maria Radu

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20071173%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

language of work or name

English

0 references

publication date

12 January 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20071173%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

number of pages

10

1 reference

inferred from page(s)

published in

Trends in Cell Biology

1 reference

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16 January 2020

volume

20

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16 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20071173%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

page(s)

160-169

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20071173%20AND%20SRC:MED&resulttype=core&format=json

Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions

16 January 2020

cites work

1 reference

12 December 2020

Reciprocal Signaling between Heterotrimeric G Proteins and the p21-stimulated Protein Kinase

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12 December 2020

Activation of the PAK-related kinase by human immunodeficiency virus type 1 Nef in primary human peripheral blood lymphocytes and macrophages leads to phosphorylation of a PIX-p95 complex

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12 December 2020

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

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12 December 2020

Identification of the Nef-associated kinase as p21-activated kinase 2

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12 December 2020

p21-activated kinase 1 plays a critical role in cellular activation by Nef.

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12 December 2020

Simian immunodeficiency virus containing mutations in N-terminal tyrosine residues and in the PxxP motif in Nef replicates efficiently in rhesus macaques

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12 December 2020

Regulation of macropinocytosis by p21-activated kinase-1

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12 December 2020

Lentivirus Nef specifically activates Pak2.

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12 December 2020

Expression of herpes simplex virus type 2 US3 affects the Cdc42/Rac pathway and attenuates c-Jun N-terminal kinase activation

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12 December 2020

p21-activated protein kinase gamma-PAK suppresses programmed cell death of BALB3T3 fibroblasts

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12 December 2020

Cytoskeletal changes regulated by the PAK4 serine/threonine kinase are mediated by LIM kinase 1 and cofilin

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12 December 2020

Effect of the deletion of US2 and US3 from herpes simplex virus type 2 on immune responses in the murine vagina following intravaginal infection

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12 December 2020

Poxvirus infection rapidly activates tyrosine kinase signal transduction

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12 December 2020

HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals

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12 December 2020

Phosphatidylserine (PS) induces PS receptor-mediated macropinocytosis and promotes clearance of apoptotic cells

1 reference

12 December 2020

p21-activated kinases: three more join the Pak.

1 reference

12 December 2020

Interaction between Nef and phosphatidylinositol-3-kinase leads to activation of p21-activated kinase and increased production of HIV

1 reference

12 December 2020

Cloning and characterization of PAK5, a novel member of mammalian p21-activated kinase-II subfamily that is predominantly expressed in brain

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12 December 2020

p21-activated kinase 1 interacts with and phosphorylates histone H3 in breast cancer cells

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12 December 2020

Cell cycle-regulated phosphorylation of p21-activated kinase 1.

1 reference

12 December 2020

Pak1 phosphorylation on t212 affects microtubules in cells undergoing mitosis

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12 December 2020

p21-activated kinase 1 (PAK1) interacts with the Grb2 adapter protein to couple to growth factor signaling

1 reference

12 December 2020

Role of the serine-threonine kinase PAK-1 in myxoma virus replication

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12 December 2020

Caspase-activated PAK-2 is regulated by subcellular targeting and proteasomal degradation

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12 December 2020

Signaling but not trafficking function of HIV-1 protein Nef is essential for Nef-induced defects in human intrathymic T-cell development

1 reference

12 December 2020

Pseudorabies virus US3 protein kinase mediates actin stress fiber breakdown

1 reference

12 December 2020

Activation of p21-activated kinase 1-nuclear factor kappaB signaling by Kaposi's sarcoma-associated herpes virus G protein-coupled receptor during cellular transformation

1 reference

12 December 2020

HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis

1 reference

12 December 2020

Human immunodeficiency virus type 1 Nef activates p21-activated kinase via recruitment into lipid rafts

1 reference

12 December 2020

Disruption of the actin cytoskeleton can complement the ability of Nef to enhance human immunodeficiency virus type 1 infectivity

1 reference

12 December 2020

Rac1 and PAK1 are upstream of IKK-epsilon and TBK-1 in the viral activation of interferon regulatory factor-3.

1 reference

12 December 2020

Dynein light chain 1, a p21-activated kinase 1-interacting substrate, promotes cancerous phenotypes

1 reference

12 December 2020

Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptors

1 reference

12 December 2020

The pseudorabies virus serine/threonine kinase Us3 contains mitochondrial, nuclear and membrane localization signals

1 reference

12 December 2020

Phosphorylation of RhoGDI by Pak1 mediates dissociation of Rac GTPase

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12 December 2020

Phosphorylation of Mnk1 by caspase-activated Pak2/gamma-PAK inhibits phosphorylation and interaction of eIF4G with Mnk

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12 December 2020

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12 December 2020

The enigmatic X gene of hepatitis B virus

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12 December 2020

Nef associates with p21-activated kinase 2 in a p21-GTPase-dependent dynamic activation complex within lipid rafts.

1 reference

12 December 2020

PAK and other Rho-associated kinases--effectors with surprisingly diverse mechanisms of regulation

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12 December 2020

Role of JNK activation in apoptosis: a double-edged sword

1 reference

12 December 2020

The protein encoded by the US3 orthologue of Marek's disease virus is required for efficient de-envelopment of perinuclear virions and involved in actin stress fiber breakdown

1 reference

12 December 2020

p21-activated Kinase 1 (Pak1)-dependent phosphorylation of Raf-1 regulates its mitochondrial localization, phosphorylation of BAD, and Bcl-2 association

1 reference

12 December 2020

Cytoskeletal rearrangements and cell extensions induced by the US3 kinase of an alphaherpesvirus are associated with enhanced spread

1 reference

12 December 2020

Pak4 induces premature senescence via a pathway requiring p16INK4/p19ARF and mitogen-activated protein kinase signaling

1 reference

12 December 2020

Functional analysis of HIV type 1 Nef reveals a role for PAK2 as a regulator of cell phenotype and function in the murine dendritic cell line, DC2.4.

1 reference

12 December 2020

Inhibition of cap-dependent translation via phosphorylation of eIF4G by protein kinase Pak2

1 reference

12 December 2020

Activation of p21-activated kinase 2 by human immunodeficiency virus type 1 Nef induces merlin phosphorylation

1 reference

12 December 2020

"UnPAKing" human immunodeficiency virus (HIV) replication: using small interfering RNA screening to identify novel cofactors and elucidate the role of group I PAKs in HIV infection

1 reference

12 December 2020

Identification of a novel pathway essential for the immediate-early, interferon-independent antiviral response to enveloped virions

1 reference

12 December 2020

Viral interactions with the cytoskeleton: a hitchhiker's guide to the cell

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12 December 2020

The HIV-1 pathogenicity factor Nef interferes with maturation of stimulatory T-lymphocyte contacts by modulation of N-Wasp activity

1 reference

12 December 2020

Human immunodeficiency virus type-1 infection impairs the formation of the immunological synapse

1 reference

12 December 2020

CD4 and MHC-I downregulation are conserved in primary HIV-1 Nef alleles from brain and lymphoid tissues, but Pak2 activation is highly variable

1 reference

12 December 2020

The KSHV and other human herpesviral G protein-coupled receptors

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12 December 2020

Hepatitis B virus-induced oncogenesis.

1 reference

12 December 2020

p21-activated kinase 1 is activated through the mammalian target of rapamycin/p70 S6 kinase pathway and regulates the replication of hepatitis C virus in human hepatoma cells

1 reference

12 December 2020

Retroviruses can establish filopodial bridges for efficient cell-to-cell transmission.

1 reference

12 December 2020

Modulation of the immunological synapse: a key to HIV-1 pathogenesis?

1 reference

12 December 2020

Hepatitis B virus X protein stimulates the mitochondrial translocation of Raf-1 via oxidative stress

1 reference

12 December 2020

2-amino-N-{4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl} acetamide (OSU-03012), a celecoxib derivative, directly targets p21-activated kinase

1 reference

12 December 2020

Association of Nef with p21-activated kinase 2 is dispensable for efficient human immunodeficiency virus type 1 replication and cytopathicity in ex vivo-infected human lymphoid tissue

1 reference

12 December 2020

HIV-1 Nef employs two distinct mechanisms to modulate Lck subcellular localization and TCR induced actin remodeling

1 reference

12 December 2020

Human immunodeficiency virus type 1 Nef recruits the guanine exchange factor Vav1 via an unexpected interface into plasma membrane microdomains for association with p21-activated kinase 2 activity

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12 December 2020

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12 December 2020

Subversion of CtBP1-controlled macropinocytosis by human adenovirus serotype 3.

1 reference

12 December 2020

The closure of Pak1-dependent macropinosomes requires the phosphorylation of CtBP1/BARS.

1 reference

12 December 2020

Pak1 and Pak2 mediate tumor cell invasion through distinct signaling mechanisms

1 reference

12 December 2020

An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase

1 reference

12 December 2020

Membrane nanotubes: dynamic long-distance connections between animal cells

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12 December 2020

Vaccinia virus uses macropinocytosis and apoptotic mimicry to enter host cells

1 reference

12 December 2020

A Raft-derived, Pak1-regulated entry participates in alpha2beta1 integrin-dependent sorting to caveosomes

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12 December 2020

Intercellular transfer mediated by tunneling nanotubes

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12 December 2020

HIV-1 Nef: at the crossroads

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12 December 2020

PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics

1 reference

12 December 2020

Targeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium Complexes

1 reference

12 December 2020

PAK signalling in neuronal physiology

1 reference

12 December 2020

p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics

1 reference

12 December 2020

The kinase activity of pseudorabies virus US3 is required for modulation of the actin cytoskeleton

1 reference

12 December 2020

Pak protein kinases and their role in cancer

1 reference

12 December 2020

Prions tunnel between cells.

1 reference

12 December 2020

Virus entry by macropinocytosis

1 reference

12 December 2020

Alphaherpesvirus US3-mediated reorganization of the actin cytoskeleton is mediated by group A p21-activated kinases

1 reference

12 December 2020

Adenovirus receptors and their implications in gene delivery

1 reference

12 December 2020

HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits

1 reference

12 December 2020

HIV-1 Nef interferes with host cell motility by deregulation of Cofilin

1 reference

12 December 2020

Intrusive HIV-1-infected cells

1 reference

12 December 2020

An allosteric kinase inhibitor binds the p21-activated kinase autoregulatory domain covalently.

1 reference

12 December 2020

Inhibition of T-cell receptor-induced actin remodeling and relocalization of Lck are evolutionarily conserved activities of lentiviral Nef proteins

1 reference

12 December 2020

Appraising the apoptotic mimicry model and the role of phospholipids for poxvirus entry

1 reference

12 December 2020

Analysis of filamentous process induction and nuclear localization properties of the HSV-2 serine/threonine kinase Us3.

1 reference

12 December 2020

A conserved domain and membrane targeting of Nef from HIV and SIV are required for association with a cellular serine kinase activity

1 reference

12 December 2020

Inactivation of glycoprotein gE and thymidine kinase or the US3-encoded protein kinase synergistically decreases in vivo replication of pseudorabies virus and the induction of protective immunity

1 reference

12 December 2020

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1 reference

12 December 2020

Human immunodeficiency virus type 1 Nef associates with a cellular serine kinase in T lymphocytes

1 reference

12 December 2020

Human immunodeficiency virus type 1 Nef associates with a member of the p21-activated kinase family

1 reference

12 December 2020

Activation of PAK by HIV and SIV Nef: importance for AIDS in rhesus macaques

1 reference

12 December 2020

CDC42 and Rac1 are implicated in the activation of the Nef-associated kinase and replication of HIV-1.

1 reference

12 December 2020

Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes

1 reference

12 December 2020

Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2

1 reference

12 December 2020

Association of simian immunodeficiency virus Nef with cellular serine/threonine kinases is dispensable for the development of AIDS in rhesus macaques

1 reference

12 December 2020

Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300.

1 reference

12 December 2020

Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation

1 reference

12 December 2020

Role of the SH3-ligand domain of simian immunodeficiency virus Nef in interaction with Nef-associated kinase and simian AIDS in rhesus macaques

1 reference

12 December 2020

Characterization of Pak2p, a pleckstrin homology domain-containing, p21-activated protein kinase from fission yeast

1 reference

12 December 2020

Adenovirus endocytosis requires actin cytoskeleton reorganization mediated by Rho family GTPases.

1 reference

12 December 2020

10.1016/J.TCB.2009.12.005

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20071173%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20071173%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

PubMed publication ID

20071173

1 reference