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PAK signalling in neuronal physiology
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scholarly article
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review article
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Europe PubMed Central
title
PAK signalling in neuronal physiology
(English)
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main subject
P21 (RAC1) activated kinase 3
1 reference
stated in
GOA release 2020-03-11
dendritic spine morphogenesis
1 reference
stated in
GOA release 2020-03-11
physiology
0 references
author name string
Patricia Kreis
series ordinal
1
0 references
Jean-Vianney Barnier
series ordinal
2
0 references
language of work or name
English
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publication date
March 2009
0 references
published in
Cellular Signalling
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volume
21
0 references
issue
3
0 references
page(s)
384-93
0 references
cites work
Missense mutation in PAK3, R67C, causes X-linked nonspecific mental retardation.
1 reference
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X-linked mild non-syndromic mental retardation with neuropsychiatric problems and the missense mutation A365E in PAK3.
1 reference
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PAK3 related mental disability: further characterization of the phenotype
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Crossref
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
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Fission yeast pak1+ encodes a protein kinase that interacts with Cdc42p and is involved in the control of cell polarity and mating.
1 reference
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Crossref
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p21-Activated kinase-1 is necessary for depolarization-mediated neuronal survival
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
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Reduced cortical synaptic plasticity and GluR1 expression associated with fragile X mental retardation protein deficiency.
1 reference
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Crossref
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Pak1 is involved in dendrite initiation as a downstream effector of Rac1 in cortical neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
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Differential distribution of alpha and beta isoforms of p21-activated kinase in the monkey cerebral neocortex and hippocampus
1 reference
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Crossref
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Hyperactivity and novelty-induced hyperreactivity in mice lacking Rac3.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
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7 January 2021
based on heuristic
inferred from DOI database lookup
Expression analysis of actin-related genes as an underlying mechanism for mood disorders
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
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7 January 2021
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A Rac-cGMP signaling pathway
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
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7 January 2021
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What turns CREB on?
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular mechanisms of dendritic spine morphogenesis
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
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7 January 2021
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The Cool-2/alpha-Pix protein mediates a Cdc42-Rac signaling cascade
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The PAR proteins: fundamental players in animal cell polarization
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
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7 January 2021
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inferred from DOI database lookup
Phylogenetic and structural analysis of the Drosophila melanogaster p21-activated kinase DmPAK3.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
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7 January 2021
based on heuristic
inferred from DOI database lookup
The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
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7 January 2021
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inferred from DOI database lookup
Synaptic dysfunction and disruption of postsynaptic drebrin-actin complex: a study of neurological disorders accompanied by cognitive deficits.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
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7 January 2021
based on heuristic
inferred from DOI database lookup
Altered cortical synaptic morphology and impaired memory consolidation in forebrain- specific dominant-negative PAK transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
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7 January 2021
based on heuristic
inferred from DOI database lookup
The Rac1-GEF Tiam1 couples the NMDA receptor to the activity-dependent development of dendritic arbors and spines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
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7 January 2021
based on heuristic
inferred from DOI database lookup
Serotonin-induced regulation of the actin network for learning-related synaptic growth requires Cdc42, N-WASP, and PAK in Aplysia sensory neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dlx transcription factors promote migration through repression of axon and dendrite growth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kalirin-7 controls activity-dependent structural and functional plasticity of dendritic spines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activity-dependent synaptogenesis: regulation by a CaM-kinase kinase/CaM-kinase I/betaPIX signaling complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synaptic plasticity and cell cycle activation in neurons are alternative effector pathways: the 'Dr. Jekyll and Mr. Hyde concept' of Alzheimer's disease or the yin and yang of neuroplasticity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
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7 January 2021
based on heuristic
inferred from DOI database lookup
The mGluR theory of fragile X mental retardation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The serine/threonine kinase dPak is required for polarized assembly of F-actin bundles and apical-basal polarity in the Drosophila follicular epithelium
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumorhead distribution to cytoplasmic membrane of neural plate cells is positively regulated by Xenopus p21-activated kinase 1 (X-PAK1).
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
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7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation of Rho GTPase effector pathways during axon development.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
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7 January 2021
based on heuristic
inferred from DOI database lookup
Biochemical characterization of Alsin, a Rab5 and Rac1 guanine nucleotide exchange factor
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
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7 January 2021
based on heuristic
inferred from DOI database lookup
Rho proteins, mental retardation and the neurobiological basis of intelligence
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pak functions downstream of Dock to regulate photoreceptor axon guidance in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Trio combines with dock to regulate Pak activity during photoreceptor axon pathfinding in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Drosophila photoreceptor axon guidance and targeting requires the dreadlocks SH2/SH3 adapter protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activity-dependent regulation of genes implicated in X-linked non-specific mental retardation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Plexin B mediates axon guidance in Drosophila by simultaneously inhibiting active Rac and enhancing RhoA signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abnormal spine morphology and enhanced LTP in LIMK-1 knockout mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rapid induction of dendritic spine morphogenesis by trans-synaptic ephrinB-EphB receptor activation of the Rho-GEF kalirin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Slit Stimulation Recruits Dock and Pak to the Roundabout Receptor and Increases Rac Activity to Regulate Axon Repulsion at the CNS Midline
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle-regulated phosphorylation of p21-activated kinase 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pak1 phosphorylation on t212 affects microtubules in cells undergoing mitosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chp, a homologue of the GTPase Cdc42Hs, activates the JNK pathway and is implicated in reorganizing the actin cytoskeleton
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Ste20 group kinases as regulators of MAP kinase cascades
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Merlin, the Product of the Nf2 Tumor Suppressor Gene, Is an Inhibitor of the p21-Activated Kinase, Pak1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PAK3 mutation in nonsyndromic X-linked mental retardation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of cofilin by LIM-kinase is necessary for semaphorin 3A-induced growth cone collapse.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel splice mutation in PAK3 gene underlying mental retardation with neuropsychiatric features
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The closure of Pak1-dependent macropinosomes requires the phosphorylation of CtBP1/BARS.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurite arborization and mosaic spacing in the mouse retina require DSCAM.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A hippocampal Cdk5 pathway regulates extinction of contextual fear
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
EphB receptors regulate dendritic spine development via intersectin, Cdc42 and N-WASP.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p21-activated kinases in cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
How did alternative splicing evolve?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian Rho GTPases: new insights into their functions from in vivo studies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MAPK cascade signalling and synaptic plasticity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PDZ domain proteins of synapses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional inactivation of a transcriptional corepressor by a signaling kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An essential role of Pak1 phosphorylation of SHARP in Notch signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The kinase-inhibitory domain of p21-activated kinase 1 (PAK1) inhibits cell cycle progression independent of PAK1 kinase activity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuregulin and laminin stimulate phosphorylation of the NF2 tumor suppressor in Schwann cells by distinct protein kinase A and p21-activated kinase-dependent pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A tale of two Paks
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autophosphorylation-dependent degradation of Pak1, triggered by the Rho-family GTPase, Chp.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of p21-activated kinase rescues symptoms of fragile X syndrome in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a mouse p21Cdc42/Rac activated kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification and Molecular Cloning of a p21cdc42/rac1-activated Serine/Threonine Kinase That Is Rapidly Activated by Thrombin in Platelets
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of RAC3, a novel member of the Rho family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural requirements for PAK activation by Rac GTPases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel regulator of p21-activated kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage and activation of p21-activated protein kinase gamma-PAK by CPP32 (caspase 3). Effects of autophosphorylation on activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Akt proto-oncogene links Ras to Pak and cell survival signals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulatable Expression of p21-activated Kinase-1 Promotes Anchorage-independent Growth and Abnormal Organization of Mitotic Spindles in Human Epithelial Breast Cancer Cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mechanism of PAK activation. Autophosphorylation events in both regulatory and kinase domains control activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of small GTPase signaling pathways using p21-activated kinase mutants that selectively couple to Cdc42.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of Pak1 by the p35/Cdk5 kinase affects neuronal morphology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the Cool/Pix proteins: key binding partners of the Cdc42/Rac targets, the p21-activated kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new constitutively active brain PAK3 isoform displays modified specificities toward Rac and Cdc42 GTPases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Shank family of postsynaptic density proteins interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Down syndrome cell adhesion molecule (DSCAM) interacts with and activates Pak.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear localization and chromatin targets of p21-activated kinase 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
LIM kinase and slingshot are critical for neurite extension
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p21-activated kinase 3 implicated in mental retardation regulates spine morphogenesis through a Cdc42-dependent pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p21-activated kinase-aberrant activation and translocation in Alzheimer disease pathogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stimulation of NFkappa B activity by multiple signaling pathways requires PAK1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The neurite outgrowth multiadaptor RhoGAP, NOMA-GAP, regulates neurite extension through SHP2 and Cdc42
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
LIMK1 regulates Golgi dynamics, traffic of Golgi-derived vesicles, and process extension in primary cultured neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurabin-I is phosphorylated by Cdk5: implications for neuronal morphogenesis and cortical migration.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PAK promotes morphological changes by acting upstream of Rac.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Membrane targeting of p21-activated kinase 1 (PAK1) induces neurite outgrowth from PC12 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
XPak3 promotes cell cycle withdrawal during primary neurogenesis in Xenopus laevis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p21-activated kinase 1 interacts with and phosphorylates histone H3 in breast cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p21-activated kinase 1 promotes soluble mutant huntingtin self-interaction and enhances toxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Scrib regulates PAK activity during the cell migration process
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of the Rho GTPases in neuronal development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signal transduction in Alzheimer disease: p21-activated kinase signaling requires C-terminal cleavage of APP at Asp664.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Steady-state increase of cAMP-response element binding protein, Rac, and PAK signaling in presenilin-deficient neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The four mammalian splice variants encoded by the p21-activated kinase 3 gene have different biological properties
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction between PAK and nck: a template for Nck targets and role of PAK autophosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt Phosphorylation of Serine 21 on Pak1 Modulates Nck Binding and Cell Migration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Outgrowth of neurites from NIE-115 neuroblastoma cells is prevented on repulsive substrates through the action of PAK.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biology of the p21-activated kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pak-1 expression increases with progression of colorectal carcinomas to metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylated Pak1 level in the cytoplasm correlates with shorter survival time in patients with glioblastoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A microarray study of gene and protein regulation in human and rat brain following middle cerebral artery occlusion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genome-wide review of transcriptional complexity in mouse protein kinases and phosphatases.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dock and Pak regulate olfactory axon pathfinding in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Caenorhabditis elegans P21-activated kinases are differentially required for UNC-6/netrin-mediated commissural motor axon guidance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Small GTPase Tc10 and its homologue RhoT induce N-WASP-mediated long process formation and neurite outgrowth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The genetics of Pak.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
betaPIX controls cell motility and neurite extension by regulating the distribution of GIT1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of polarized protrusion formation on neuronal precursors migrating in the developing chicken cerebellum
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequential implication of the mental retardation proteins ARHGEF6 and PAK3 in spine morphogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Central nervous system functions of PAK protein family: from spine morphogenesis to mental retardation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abnormal long-lasting synaptic plasticity and cognition in mice lacking the mental retardation gene Pak3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Changes in synaptic morphology accompany actin signaling during LTP.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Localized activation of p21-activated kinase controls neuronal polarity and morphology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deleted in colorectal cancer binding netrin-1 mediates cell substrate adhesion and recruits Cdc42, Rac1, Pak1, and N-WASP into an intracellular signaling complex that promotes growth cone expansion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of X-linked mental retardation gene oligophrenin1 in mice impairs spatial memory and leads to ventricular enlargement and dendritic spine immaturity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of growth cone motility and morphology by LIM kinase and Slingshot via phosphorylation and dephosphorylation of cofilin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA synthesis and neuronal apoptosis caused by familial Alzheimer disease mutants of the amyloid precursor protein are mediated by the p21 activated kinase PAK3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Src-dependent tyrosine phosphorylation at the tips of growth cone filopodia promotes extension.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mental retardation protein PAK3 contributes to synapse formation and plasticity in hippocampus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A GIT1/PIX/Rac/PAK signaling module regulates spine morphogenesis and synapse formation through MLC
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Brain-derived neurotrophic factor promotes long-term potentiation-related cytoskeletal changes in adult hippocampus.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2008.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/J.CELLSIG.2008.11.001
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1994375
OpenCitations bibliographic resource ID
1994375
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1994375
PubMed publication ID
19036346
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1994375
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