(Q38297631)

1 September 2017

title

Analysis of small GTPase signaling pathways using p21-activated kinase mutants that selectively couple to Cdc42. (English)

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1 September 2017

Reeder MK

1

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1 September 2017

Serebriiskii IG

series ordinal

2

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1 September 2017

Golemis EA

series ordinal

3

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1 September 2017

Chernoff J

series ordinal

4

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1 September 2017

language of work or name

English

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publication date

20 August 2001

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Journal of Biological Chemistry

1 September 2017

number of pages

8

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based on heuristic

inferred from page(s)

published in

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1 September 2017

volume

276

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1 September 2017

issue

44

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1 September 2017

page(s)

40606-40613

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Rho GTPases and the actin cytoskeleton

1 September 2017

cites work

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An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

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Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

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Regulation of phosphorylation pathways by p21 GTPases. The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways

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p21-activated protein kinase: a crucial component of morphological signaling?

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Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

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Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes

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Differential effects of PAK1-activating mutations reveal activity-dependent and -independent effects on cytoskeletal regulation

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p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts

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A role for p21-activated kinase in endothelial cell migration.

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Activation of hPAK65 by caspase cleavage induces some of the morphological and biochemical changes of apoptosis

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Stimulation of NFkappa B activity by multiple signaling pathways requires PAK1.

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Signals from the Ras, Rac, and Rho GTPases converge on the Pak protein kinase in Rat-1 fibroblasts

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The Akt proto-oncogene links Ras to Pak and cell survival signals

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Localization of p21-activated kinase 1 (PAK1) to pinocytic vesicles and cortical actin structures in stimulated cells

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Insulin activates a p21-activated kinase in muscle cells via phosphatidylinositol 3-kinase

21 January 2018

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Activation of Rac and Cdc42 by integrins mediates cell spreading

21 January 2018

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Tools of the trade: use of dominant-inhibitory mutants of Ras-family GTPases

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Structural requirements for PAK activation by Rac GTPases

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Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

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A two-hybrid dual bait system to discriminate specificity of protein interactions

21 January 2018

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Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation

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Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization

21 January 2018

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Distinct cellular effects and interactions of the Rho-family GTPase TC10.

21 January 2018

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Genghis Khan (Gek) as a putative effector for Drosophila Cdc42 and regulator of actin polymerization

21 January 2018

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Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

21 January 2018

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Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

21 January 2018

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PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia

21 January 2018

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21 January 2018

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SPECs, small binding proteins for Cdc42

21 January 2018

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A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1.

21 January 2018

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PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

21 January 2018

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A novel regulator of p21-activated kinases

21 January 2018

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Identification of a mouse p21Cdc42/Rac activated kinase

21 January 2018

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Interaction of the Nck adapter protein with p21-activated kinase (PAK1)

21 January 2018

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A brain serine/threonine protein kinase activated by Cdc42 and Rac1

21 January 2018

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A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

21 January 2018

1 reference

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Structure of Cdc42 bound to the GTPase binding domain of PAK

21 January 2018

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Residues in Cdc42 that specify binding to individual CRIB effector proteins

21 January 2018

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Sphingosine is a novel activator of 3-phosphoinositide-dependent kinase 1.

21 January 2018

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The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1

21 January 2018

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p21-activated Protein Kinase γ-PAK Is Activated by Ionizing Radiation and Other DNA-damaging Agents

21 January 2018

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Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2

21 January 2018

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Direct random mutagenesis of gene-sized DNA fragments using polymerase chain reaction

21 January 2018

1 reference

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Delineation of the Cdc42/Rac-binding domain of p21-activated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103925200

Identification of the binding surface on Cdc42Hs for p21-activated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103925200

21 January 2018

Identifiers

DOI

10.1074/JBC.M103925200

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1 September 2017

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