(Q33306697)

25 July 2017

HIV-1 Nef employs two distinct mechanisms to modulate Lck subcellular localization and TCR induced actin remodeling (English)

1 reference

25 July 2017

Oliver T Fackler

3

0 references

author name string

Claudia Haller

series ordinal

1

1 reference

PubMed ID

18030346

25 July 2017

Susanne Rauch

series ordinal

2

1 reference

PubMed ID

18030346

25 July 2017

language of work or name

English

0 references

publication date

21 November 2007

1 reference

25 July 2017

1 reference

25 July 2017

2

1 reference

25 July 2017

11

1 reference

25 July 2017

e1212

1 reference

Creative Commons Attribution 4.0 International

25 July 2017

start time

21 November 2007

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2075162/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Modulation of the immunological synapse: a key to HIV-1 pathogenesis?

21 June 2018

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21 June 2018

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Regulation of T-cell activation by the cytoskeleton

21 June 2018

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Specific and distinct determinants mediate membrane binding and lipid raft incorporation of HIV-1(SF2) Nef.

21 June 2018

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The Pro78 residue regulates the capacity of the human immunodeficiency virus type 1 Nef protein to inhibit recycling of major histocompatibility complex class I molecules in an SH3-independent manner

21 June 2018

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Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1

21 June 2018

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The Nef protein of human immunodeficiency virus is a broad-spectrum modulator of chemokine receptor cell surface levels that acts independently of classical motifs for receptor endocytosis and Galphai signaling

21 June 2018

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The HIV-1 pathogenicity factor Nef interferes with maturation of stimulatory T-lymphocyte contacts by modulation of N-Wasp activity

21 June 2018

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21 June 2018

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A hydrophobic binding surface on the human immunodeficiency virus type 1 Nef core is critical for association with p21-activated kinase 2.

21 June 2018

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Modulation of specific surface receptors and activation sensitization in primary resting CD4+ T lymphocytes by the Nef protein of HIV-1.

21 June 2018

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Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling

21 June 2018

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Human immunodeficiency virus (HIV)-1 proteins and cytoskeleton: partners in viral life and host cell death

21 June 2018

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The T cell receptor: critical role of the membrane environment in receptor assembly and function

21 June 2018

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Oligomerization of the diaphanous-related formin FHOD1 requires a coiled-coil motif critical for its cytoskeletal and transcriptional activities

21 June 2018

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HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail

21 June 2018

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CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse

21 June 2018

1 reference

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Human immunodeficiency virus type 1 Nef activates p21-activated kinase via recruitment into lipid rafts

21 June 2018

1 reference

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Regulation of sustained actin dynamics by the TCR and costimulation as a mechanism of receptor localization

21 June 2018

1 reference

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21 June 2018

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HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway

21 June 2018

1 reference

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T cell receptor ligation induces the formation of dynamically regulated signaling assemblies

21 June 2018

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Function of dynein and dynactin in herpes simplex virus capsid transport

21 June 2018

1 reference

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Structure--function relationships in HIV-1 Nef.

21 June 2018

1 reference

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Synergistic activation of NFAT by HIV-1 nef and the Ras/MAPK pathway

21 June 2018

1 reference

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HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes

21 June 2018

1 reference

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The Nef protein of HIV-1 associates with rafts and primes T cells for activation

21 June 2018

1 reference

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HIV-1 Nef increases T cell activation in a stimulus-dependent manner

21 June 2018

1 reference

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Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-I trafficking

21 June 2018

1 reference

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SH3-Domain binding function of HIV-1 Nef is required for association with a PAK-related kinase

21 June 2018

1 reference

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Interactions between HIV1 Nef and vacuolar ATPase facilitate the internalization of CD4

21 June 2018

1 reference

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Cytoskeletal polarization of T cells is regulated by an immunoreceptor tyrosine-based activation motif-dependent mechanism

21 June 2018

1 reference

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T cell antigen receptor signal transduction pathways

21 June 2018

1 reference

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Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075162

Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

21 June 2018

1 reference

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A conserved domain and membrane targeting of Nef from HIV and SIV are required for association with a cellular serine kinase activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075162

Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075162

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075162

Human immunodeficiency virus type-1 infection impairs the formation of the immunological synapse

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001212

Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001212

T cell glycolipid-enriched membrane domains are constitutively assembled as membrane patches that translocate to immune synapses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001212

CD28 and lipid rafts coordinate recruitment of Lck to the immunological synapse of human T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001212

The Nef protein of human immunodeficiency virus establishes superinfection immunity by a dual strategy to downregulate cell-surface CCR5 and CD4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001212

Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001212

The N-Terminus of Nef from HIV-1/SIV Associates with a Protein Complex Containing Lck and a Serine Kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001212

HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18030346

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0001212

1 reference

25 July 2017

0 references

1 reference

25 July 2017

1 reference

PubMed ID

18030346