(Q40242493)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16916529%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

title

Specific and distinct determinants mediate membrane binding and lipid raft incorporation of HIV-1(SF2) Nef (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16916529%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16916529%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Oliver T Fackler

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16916529%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

author name string

Simone I Giese

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16916529%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Ilka Woerz

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16916529%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Stefanie Homann

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16916529%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Nadine Tibroni

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16916529%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

language of work or name

English

0 references

publication date

17 August 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16916529%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16916529%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

volume

355

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16916529%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16916529%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

page(s)

175-191

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16916529%20AND%20SRC:MED&resulttype=core&format=json

Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

28 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Mutational analysis of HIV-1 Nef: identification of two mutants that are temperature-sensitive for CD4 downregulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Human immunodeficiency virus type 1 Nef associates with lipid rafts to downmodulate cell surface CD4 and class I major histocompatibility complex expression and to increase viral infectivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Lentivirus Nef specifically activates Pak2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Nef: agent of cell subversion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

The N-Terminus of Nef from HIV-1/SIV Associates with a Protein Complex Containing Lck and a Serine Kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

The di-leucine motif in the cytoplasmic tail of CD4 is not required for binding to human immunodeficiency virus type 1 Nef, but is critical for CD4 down-modulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Role of myristoylation and N-terminal basic residues in membrane association of the human immunodeficiency virus type 1 Nef protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Biochemical indication for myristoylation-dependent conformational changes in HIV-1 Nef.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

The HIV lipidome: a raft with an unusual composition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Structural defects and variations in the HIV-1 nef gene from rapid, slow and non-progressor children

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Protein Kinase C-mediated Phosphorylation of HIV-I Nef in Human Cell Lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Nef binds p6* in GagPol during replication of human immunodeficiency virus type 1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Interactions of HIV-1 nef with the mu subunits of adaptor protein complexes 1, 2, and 3: role of the dileucine-based sorting motif

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Association of human immunodeficiency virus Nef protein with actin is myristoylation dependent and influences its subcellular localization.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

p21-activated kinase 1 plays a critical role in cellular activation by Nef.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

A natural variability in the proline-rich motif of Nef modulates HIV-1 replication in primary T cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Functional characterization of HIV-1 Nef mutants in the context of viral infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Hyper-responsiveness to stimulation of human immunodeficiency virus-infected CD4+ T cells requires Nef and Tat virus gene products and results from higher NFAT, NF-kappaB, and AP-1 induction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

The Dually Acylated NH2-terminal Domain of Gi1αIs Sufficient to Target a Green Fluorescent Protein Reporter to Caveolin-enriched Plasma Membrane Domains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Serine phosphorylation-independent downregulation of cell-surface CD4 by nef

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Domain assembly, surface accessibility and sequence conservation in full length HIV-1 Nef.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Structure of the anchor-domain of myristoylated and non-myristoylated HIV-1 Nef protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Structure--function relationships in HIV-1 Nef.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Cellular distribution of HIV type 1 Nef protein: identification of domains in Nef required for association with membrane and detergent-insoluble cellular matrix

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Rodent cells support key functions of the human immunodeficiency virus type 1 pathogenicity factor Nef

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Modulation of specific surface receptors and activation sensitization in primary resting CD4+ T lymphocytes by the Nef protein of HIV-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Human immunodeficiency virus type 1 Nef activates p21-activated kinase via recruitment into lipid rafts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

The physiological relevance of CD4 receptor down-modulation during HIV infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

The N-terminal SH4 region of the Src family kinase Fyn is modified by methylation and heterogeneous fatty acylation: role in membrane targeting, cell adhesion, and spreading

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Functional roles for fatty acylated amino-terminal domains in subcellular localization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

N-terminal protein acylation confers localization to cholesterol, sphingolipid-enriched membranes but not to lipid rafts/caveolae

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

The Nef protein of human immunodeficiency virus establishes superinfection immunity by a dual strategy to downregulate cell-surface CCR5 and CD4.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

The Nef protein of human immunodeficiency virus is a broad-spectrum modulator of chemokine receptor cell surface levels that acts independently of classical motifs for receptor endocytosis and Galphai signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Construction and characterization of a fluorescently labeled infectious human immunodeficiency virus type 1 derivative

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Myristoylation-enhanced binding of the HIV-1 Nef protein to T cell skeletal matrix.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Nef associates with p21-activated kinase 2 in a p21-GTPase-dependent dynamic activation complex within lipid rafts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Human immunodeficiency virus 1 Nef suppresses CD40-dependent immunoglobulin class switching in bystander B cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Reconstitution and molecular analysis of an active human immunodeficiency virus type 1 Nef/p21-activated kinase 2 complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Identification of the Nef-associated kinase as p21-activated kinase 2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Membrane targeting of lipid modified signal transduction proteins.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

CD4 down-regulation by HIV-1 and simian immunodeficiency virus (SIV) Nef proteins involves both internalization and intracellular retention mechanisms.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Therapeutic targeting of interactions between Nef and host cell proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Human immunodeficiency virus type 1 Nef associates with a cellular serine kinase in T lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

The effects of HIV-1 Nef on CD4 surface expression and viral infectivity in lymphoid cells are independent of rafts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

HIV-1 Nef impairs MHC class II antigen presentation and surface expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Human immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

HIV/SIV escape from immune surveillance: focus on Nef

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Kinetic analysis of human immunodeficiency virus type 1 assembly reveals the presence of sequential intermediates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

The Nef protein of HIV-1 associates with rafts and primes T cells for activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Human immunodeficiency virus type 1 Nef domains required for disruption of major histocompatibility complex class I trafficking are also necessary for coprecipitation of Nef with HLA-A2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Experimentally determined hydrophobicity scale for proteins at membrane interfaces

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Nef increases infectivity of HIV via lipid rafts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Virion incorporation of human immunodeficiency virus type 1 Nef is mediated by a bipartite membrane-targeting signal: analysis of its role in enhancement of viral infectivity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

inferred from DOI database lookup

7 January 2021

based on heuristic

Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-I trafficking

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.07.003

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.VIROL.2006.07.003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16916529%20AND%20SRC:MED&resulttype=core&format=json

release_gyivtw5hoje6hfqbr6zaxgnbvy

28 December 2019

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/gyivtw5hoje6hfqbr6zaxgnbvy

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference