(Q40478558)

English

CD4 down-regulation by HIV-1 and simian immunodeficiency virus (SIV) Nef proteins involves both internalization and intracellular retention mechanisms.

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scholarly article

1 reference

Europe PubMed Central

20 September 2017

CD4 down-regulation by HIV-1 and simian immunodeficiency virus (SIV) Nef proteins involves both internalization and intracellular retention mechanisms. (English)

1 reference

Europe PubMed Central

20 September 2017

Simian immunodeficiency virus

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object named as

Katy Janvier

2

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Juan S. Bonifacino

object named as

Juan S Bonifacino

5

0 references

Rafick-Pierre Sékaly

4

object named as

Rafick P Sekaly

1 reference

Europe PubMed Central

20 September 2017

author name string

Jeremy J Rose

1

1 reference

Europe PubMed Central

20 September 2017

Soundararajulu Chandrasekhar

3

1 reference

Europe PubMed Central

20 September 2017

Sundararajan Venkatesan

6

1 reference

Europe PubMed Central

20 September 2017

language of work or name

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publication date

16 December 2004

1 reference

Europe PubMed Central

20 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

20 September 2017

280

1 reference

Europe PubMed Central

20 September 2017

9

1 reference

Europe PubMed Central

20 September 2017

7413-7426

1 reference

Europe PubMed Central

20 September 2017

Signals for sorting of transmembrane proteins to endosomes and lysosomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Endocytosis and molecular sorting

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Adaptor-related proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Structure--function relationships in HIV-1 Nef.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

In vivo analysis of Nef function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Nef--an adaptor adaptor?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Cluster of differentiation antigen 4 (CD4) endocytosis and adaptor complex binding require activation of the CD4 endocytosis signal by serine phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 gamma-sigma1 and AP-3 delta-sigma3 hemicomplexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Myristoylation-dependent binding of HIV-1 Nef to CD4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Nef-CD4 physical interaction sensed with the yeast two-hybrid system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Direct in vitro binding of full-length human immunodeficiency virus type 1 Nef protein to CD4 cytoplasmic domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Distinct mechanisms of agonist-induced endocytosis for human chemokine receptors CCR5 and CXCR4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Vaccinia virus expression vector: coexpression of beta-galactosidase provides visual screening of recombinant virus plaques

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Oligomeric structure of the human immunodeficiency virus type 1 envelope glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Human immunodeficiency virus type 1 (HIV-1) provirus expression and LTR transcription are repressed in NEF-expressing cell lines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Induction of mutant dynamin specifically blocks endocytic coated vesicle formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Beta3A-adaptin, a subunit of the adaptor-like complex AP-3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Nuclear localization of a double-stranded RNA-binding protein encoded by the vaccinia virus E3L gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

The protein tyrosine kinase p56lck inhibits CD4 endocytosis by preventing entry of CD4 into coated pits

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Differential endocytosis of CD4 in lymphocytic and nonlymphocytic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

The dynamin family of mechanoenzymes: pinching in new places

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Caveolae/raft-dependent endocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Genetic analyses of adaptin function from yeast to mammals.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Interactions of HIV-1 nef with the mu subunits of adaptor protein complexes 1, 2, and 3: role of the dileucine-based sorting motif

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Nef-mediated clathrin-coated pit formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Two elements target SIV Nef to the AP-2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

HIV-1 Nef plays an essential role in two independent processes in CD4 down-regulation: dissociation of the CD4-p56(lck) complex and targeting of CD4 to lysosomes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Nef-induced CD4 downregulation: a diacidic sequence in human immunodeficiency virus type 1 Nef does not function as a protein sorting motif through direct binding to beta-COP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

The di-leucine motif in the cytoplasmic tail of CD4 is not required for binding to human immunodeficiency virus type 1 Nef, but is critical for CD4 down-modulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Dileucine-based sorting signals bind to the beta chain of AP-1 at a site distinct and regulated differently from the tyrosine-based motif-binding site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Regulation and function of the CD3gamma DxxxLL motif: a binding site for adaptor protein-1 and adaptor protein-2 in vitro.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Presence of a Helix in Human CD4 Cytoplasmic Domain Promotes Binding to HIV-1 Nef Protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Identifiers

10.1074/JBC.M409420200

1 reference

Europe PubMed Central

20 September 2017

1 reference

Europe PubMed Central

20 September 2017

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