Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q24522550)
Watch
English
Structure--function relationships in HIV-1 Nef.
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
Structure--function relationships in HIV-1 Nef
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
main subject
HIV
1 reference
based on heuristic
inferred from title
author
Matthias Geyer
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
Oliver T Fackler
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
author name string
B M Peterlin
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
language of work or name
English
0 references
publication date
1 July 2001
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
published in
EMBO Reports
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
volume
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
issue
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
page(s)
580-585
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
cites work
Mutation of a conserved residue (D123) required for oligomerization of human immunodeficiency virus type 1 Nef protein abolishes interaction with human thioesterase and results in impairment of Nef biological functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Identification of the Nef-associated kinase as p21-activated kinase 2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Binding of c-Raf1 kinase to a conserved acidic sequence within the carboxyl-terminal region of the HIV-1 Nef protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Interactions between HIV1 Nef and vacuolar ATPase facilitate the internalization of CD4
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Structure of the anchor-domain of myristoylated and non-myristoylated HIV-1 Nef protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
24 March 2017
Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
7 April 2017
The human thioesterase II protein binds to a site on HIV-1 Nef critical for CD4 down-regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
p21-activated kinase 1 plays a critical role in cellular activation by Nef.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
The structural era of endocytosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Bi-cycling the furin pathway: from TGN localization to pathogen activation and embryogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
SH3-Domain binding function of HIV-1 Nef is required for association with a PAK-related kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus Nef use distinct but overlapping target sites for downregulation of cell surface CD4.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Association of simian immunodeficiency virus Nef with cellular serine/threonine kinases is dispensable for the development of AIDS in rhesus macaques
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Refined solution structure and backbone dynamics of HIV-1 Nef.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Producer-cell modification of human immunodeficiency virus type 1: Nef is a virion protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Physical interaction of the HIV-1 Nef protein with beta-COP, a component of non-clathrin-coated vesicles essential for membrane traffic.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Human immunodeficiency virus type 1 Nef protein is incorporated into virus particles and specifically cleaved by the viral proteinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Mutational analysis of HIV-1 Nef: identification of two mutants that are temperature-sensitive for CD4 downregulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
A conserved domain and membrane targeting of Nef from HIV and SIV are required for association with a cellular serine kinase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
27 September 2017
Activation of PAK by HIV and SIV Nef: importance for AIDS in rhesus macaques
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1083955
retrieved
30 May 2018
HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1093%2FEMBO-REPORTS%2FKVE141
retrieved
21 January 2018
A possible regulation of negative factor (Nef) activity of human immunodeficiency virus type 1 by the viral protease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1093%2FEMBO-REPORTS%2FKVE141
retrieved
21 January 2018
Domain assembly, surface accessibility and sequence conservation in full length HIV-1 Nef.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1093%2FEMBO-REPORTS%2FKVE141
retrieved
21 January 2018
The role of myristoylation in the interactions between human immunodeficiency virus type I Nef and cellular proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1093%2FEMBO-REPORTS%2FKVE141
retrieved
21 January 2018
HIV-1 Nef plays an essential role in two independent processes in CD4 down-regulation: dissociation of the CD4-p56(lck) complex and targeting of CD4 to lysosomes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1093%2FEMBO-REPORTS%2FKVE141
retrieved
21 January 2018
cAMP takes control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1093%2FEMBO-REPORTS%2FKVE141
retrieved
21 January 2018
Mutational analysis of the HIV nef protein
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11463741
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1093/EMBO-REPORTS/KVE141
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
OpenCitations bibliographic resource ID
2606889
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2606889
PMC publication ID
1083955
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2606889
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
PubMed publication ID
11463741
1 reference
stated in
Europe PubMed Central
PMC publication ID
1083955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11463741%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
ResearchGate publication ID
11877987
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
