(Q36337509)

13 August 2017

A novel human multidrug resistance gene MDR1 variant G571A (G191R) modulates cancer drug resistance and efflux transport (English)

1 reference

13 August 2017

multiple drug resistance

1 reference

Ziping Yang

1

1 reference

13 August 2017

Daniel Wu

series ordinal

2

1 reference

13 August 2017

Tot Bui

series ordinal

3

1 reference

13 August 2017

Rodney J Y Ho

series ordinal

4

1 reference

13 August 2017

language of work or name

English

0 references

publication date

22 August 2008

1 reference

Journal of Pharmacology and Experimental Therapeutics

13 August 2017

1 reference

13 August 2017

327

1 reference

13 August 2017

2

1 reference

13 August 2017

474-481

1 reference

A "silent" polymorphism in the MDR1 gene changes substrate specificity

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477805

Multidrug resistance 1 gene in inflammatory bowel disease: a meta-analysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477805

Functional implications of genetic polymorphisms in the multidrug resistance gene MDR1 (ABCB1).

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477805

Development and characterization of a recombinant Madin-Darby canine kidney cell line that expresses rat multidrug resistance-associated protein 1 (rMRP1)

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477805

The role of MDR1 genetic polymorphisms in interindividual variability in P-glycoprotein expression and function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477805

Clinical relevance of P-glycoprotein in drug therapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477805

Cloning and characterization of the rat multidrug resistance-associated protein 1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477805

Semi-quantitative RT-PCR method to estimate full-length mRNA levels of the multidrug resistance gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477805

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477805

Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477805

P-glycoprotein and multidrug resistance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477805

Functional consequences of proline mutations in the predicted transmembrane domain of P-glycoprotein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477805

In vitro and in vivo reversal of multidrug resistance by GF120918, an acridonecarboxamide derivative.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477805

Mutations to amino acids located in predicted transmembrane segment 6 (TM6) modulate the activity and substrate specificity of human P-glycoprotein

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477805

Functional consequences of glycine mutations in the predicted cytoplasmic loops of P-glycoprotein

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477805

Increased expression of MDR1 mRNAs and P-glycoprotein in placentas from HIV-1 infected women.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477805

Multidrug resistance gene G1199A polymorphism alters efflux transport activity of P-glycoprotein

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477805

Simultaneous binding of two different drugs in the binding pocket of the human multidrug resistance P-glycoprotein

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477805

Functional characterization of coding polymorphisms in the human MDR1 gene using a vaccinia virus expression system.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477805

Identification of functionally variant MDR1 alleles among European Americans and African Americans

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477805

Functional consequences of phenylalanine mutations in the predicted transmembrane domain of P-glycoprotein.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477805

Communication between multiple drug binding sites on P-glycoprotein

22 September 2018

1 reference

12 December 2020

MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukemia patients

1 reference

12 December 2020

Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene

1 reference

12 December 2020

Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene

1 reference

12 December 2020

Identifiers

DOI

10.1124/JPET.108.138313

1 reference

release_btkpx4gosfh5rlh4sxxt5wv55m

13 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/btkpx4gosfh5rlh4sxxt5wv55m

24 November 2022

mapped directly with Wikidata item

1 reference

13 August 2017

PubMed publication ID

18723777

1 reference