(Q36342371)

13 August 2017

1 reference

title

Biological, cellular, and molecular characteristics of an inducible transgenic skin tumor model: a review (English)

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13 August 2017

2

Carol S Trempus

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13 August 2017

5

Raymond W Tennant

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13 August 2017

Michael C Humble

1

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13 August 2017

Judson W Spalding

series ordinal

3

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13 August 2017

Ronald E Cannon

series ordinal

4

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13 August 2017

language of work or name

English

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publication date

1 December 2005

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13 August 2017

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13 August 2017

volume

24

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13 August 2017

issue

56

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13 August 2017

page(s)

8217-8228

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Oral administration of dimethylvinyl chloride increases frequency of forestomach papillomas in Tg.AC mice

13 August 2017

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Kinetics of wound-induced v-Ha-ras transgene expression and papilloma development in transgenic Tg.AC mice

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Induction of transgene expression in Tg.AC(v-Ha-ras) transgenic mice concomitant with DNA hypomethylation.

21 January 2018

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mRNA expression and phenotype of odontogenic tumours in the v-Ha-ras transgenic mouse

21 January 2018

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Locus control regions, chromatin activation and transcription

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Developmental regulation of human globin genes

21 January 2018

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Functional copies of a human gene can be directly isolated by transformation-associated recombination cloning with a small 3' end target sequence.

21 January 2018

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Epidermal stem cells: properties, markers, and location.

21 January 2018

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v-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: effects of phorbol esters and retinoic acid

21 January 2018

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IL-1 alpha, innate immunity, and skin carcinogenesis: the effect of constitutive expression of IL-1 alpha in epidermis on chemical carcinogenesis

21 January 2018

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The role of transgenic mouse models in carcinogen identification

21 January 2018

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Expression of the bcl-2 protooncogene in the cycling adult mouse hair follicle

21 January 2018

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Identifying chemical carcinogens and assessing potential risk in short-term bioassays using transgenic mouse models

21 January 2018

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Predictions for the outcome of rodent carcinogenicity bioassays: identification of trans-species carcinogens and noncarcinogens

21 January 2018

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Loss of critical palindromic transgene promoter sequence in chemically induced Tg.AC mouse skin papillomas expressing transgene-derived mRNA.

21 January 2018

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Comparative expression of novel vascular endothelial growth factor/vascular permeability factor transcripts in skin, papillomas, and carcinomas of v-Ha-ras Tg.AC transgenic mice and FVB/N mice

21 January 2018

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Decreases in phorbol ester-induced papilloma development in v-Ha-ras transgenic TG.AC mice during reduced gene dosage of bcl-2.

21 January 2018

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Mapping of DNase I-hypersensitive sites in the upstream DNA of human embryonic epsilon-globin gene in K562 leukemia cells

21 January 2018

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An erythroid-specific, developmental-stage-independent enhancer far upstream of the human "beta-like globin" genes

21 January 2018

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Effect of in vitro DNA methylation on beta-globin gene expression

21 January 2018

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Promotion of epidermal carcinogenesis by repeated damage to mouse skin.

21 January 2018

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7 January 2021

Morphological characterization of spindle cell tumors induced in transgenic Tg.AC mouse skin.

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7 January 2021

Mouse skin carcinomas induced in vivo by chemical carcinogens have a transforming Harvey-ras oncogene

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7 January 2021

Age-dependent skin tumorigenesis and transgene expression in the Tg.AC (v-Ha-ras) transgenic mouse

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7 January 2021

Dermal carcinogenicity in transgenic mice: relative responsiveness of male and female hemizygous and homozygous Tg.AC mice to 12-O-tetradecanoylphorbol 13-acetate (TPA) and benzene.

1 reference

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7 January 2021

Ron tyrosine kinase receptor regulates papilloma growth and malignant conversion in a murine model of skin carcinogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Photocarcinogenesis in the Tg.AC mouse: lomefloxacin and 8-methoxypsoralen

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Alternative models for carcinogenicity testing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Instability of long inverted repeats within mouse transgenes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis

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7 January 2021

THE PART PLAYED BY INJURY AND REPAIR IN THE DEVELOPMENT OF CANCER

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7 January 2021

V-Ha-ras gene expression in liver and kidney of transgenic Tg.AC mice following chemically induced tissue injury

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Chemoprevention of UV light-induced skin tumorigenesis by inhibition of the epidermal growth factor receptor.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Cytogenetic analysis of malignant skin tumors induced in chemically treated TG-AC transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Arsenic can mediate skin neoplasia by chronic stimulation of keratinocyte-derived growth factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Activation by locus control regions?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Effect of the viable-yellow (A(vy)) agouti allele on skin tumorigenesis and humoral hypercalcemia in v-Ha-ras transgenic TGxAC mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Focal transgene expression associated with papilloma development in v-Ha-ras-transgenic TG.AC mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Follicular origin of epidermal papillomas in v-Ha-ras transgenic TG.AC mouse skin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Association of tumor development with increased cellular proliferation and transgene overexpression, but not c-Ha-ras mutations, in v-Ha-ras transgenic Tg.AC mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

A major positive regulatory region located far upstream of the human alpha-globin gene locus

1 reference

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7 January 2021

Radial transformation-associated recombination cloning from the mouse genome: isolation of Tg.AC transgene with flanking DNAs

1 reference

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7 January 2021

TGF alpha is dispensable for skin tumorigenesis in Tg.AC mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Characterization of the major regulatory element upstream of the human alpha-globin gene cluster

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Chemiluminescence-based method for genotyping Tg.AC responder mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

GATA-3: an unexpected regulator of cell lineage determination in skin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

VEGF/VPF overexpression in skin of transgenic mice induces angiogenesis, vascular hyperpermeability and accelerated tumor development

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7 January 2021

Long DNA palindromes, cruciform structures, genetic instability and secondary structure repair

1 reference

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7 January 2021

Genetic interaction between the unstable v-Ha-RAS transgene (Tg.AC) and the murine Werner syndrome gene: transgene instability and tumorigenesis

1 reference

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7 January 2021

Palindromic DNA and genome stability. Further studies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Spontaneous and chemically induced proliferative lesions in Tg.AC transgenic and p53-heterozygous mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Spontaneous lesions in aging FVB/N mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Diacylglycerol is an effector of the clonal expansion of cells containing activated Ha-ras genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Keratinocyte stem cells: targets for cutaneous carcinogens

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Blue light inhibits the growth of skin tumors in the v‐Ha‐ras transgenic mouse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Background and framework for ILSI's collaborative evaluation program on alternative models for carcinogenicity assessment. International Life Sciences Institute

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Evaluation of the Tg.AC transgenic mouse assay for testing the human carcinogenic potential of pharmaceuticals--practical pointers, mechanistic clues, and new questions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Co-operation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Responses of transgenic mouse lines p53(+/-) and Tg.AC to agents tested in conventional carcinogenicity bioassays

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Development of a transgenic mouse model for carcinogenesis bioassays: evaluation of chemically induced skin tumors in Tg.AC mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Chemically induced skin carcinogenesis in a transgenic mouse line (TG.AC) carrying a v-Ha-ras gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Identifying carcinogens--a strategy for use of abbreviated models.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Evaluation of transgenic mouse bioassays for identifying carcinogens and noncarcinogens

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

The Tg.AC (v-Ha-ras) transgenic mouse: nature of the model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

An evaluation of the hemizygous transgenic Tg.AC mouse for carcinogenicity testing of pharmaceuticals. II. A genotypic marker that predicts tumorigenic responsiveness.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

A farnesyl transferase inhibitor suppresses TPA-mediated skin tumor development without altering hyperplasia in the ras transgenic Tg.AC mouse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Photocarcinogenesis and susceptibility to UV radiation in the v-Ha-ras transgenic Tg.AC mouse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Association of v-Ha-ras transgene expression with development of erythroleukemia in Tg.AC transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

An evaluation of the hemizygous transgenic Tg.AC mouse for carcinogenicity testing of pharmaceuticals. I. Evidence for a confounding nonresponder phenotype

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Identification of Dss1 as a 12-O-tetradecanoylphorbol-13-acetate-responsive gene expressed in keratinocyte progenitor cells, with possible involvement in early skin tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Odontogenic tumours in the v-Ha-ras (TG.AC) transgenic mouse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209000

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209000

1 reference

13 August 2017

1 reference