(Q36349377)

13 August 2017

Evaluation of 6β-hydroxycortisol, 6β-hydroxycortisone, and a combination of the two as endogenous probes for inhibition of CYP3A4 in vivo (English)

1 reference

13 August 2017

6beta-hydroxycortisol

1 reference

ChEBI release 2020-05-28

1 reference

ChEBI release 2020-05-28

C-C Peng

1

1 reference

13 August 2017

I Templeton

2

1 reference

13 August 2017

K E Thummel

3

1 reference

13 August 2017

C Davis

4

1 reference

13 August 2017

K L Kunze

5

1 reference

13 August 2017

N Isoherranen

6

1 reference

13 August 2017

language of work or name

English

0 references

publication date

13 April 2011

1 reference

Clinical Pharmacology & Therapeutics

13 August 2017

1 reference

13 August 2017

89

1 reference

13 August 2017

6

1 reference

13 August 2017

888-895

1 reference

Accurate prediction of dose-dependent CYP3A4 inhibition by itraconazole and its metabolites from in vitro inhibition data

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481835

11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481835

Role of itraconazole metabolites in CYP3A4 inhibition

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481835

The effects of rifampicin on the pharmacokinetics and pharmacodynamics of orally administered nilvadipine to healthy subjects

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481835

Cortisol metabolism and the role of 11beta-hydroxysteroid dehydrogenase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481835

Noninvasive tests of CYP3A enzymes

30 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481835

30 September 2017

https://api.crossref.org/works/10.1038%2FCLPT.2011.53

The increase in urinary excretion of 6 beta-hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481835

Cytochrome P4503A (CYP3A) metabolism: prediction of in vivo activity in humans

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481835

Dose-dependent inhibition of CYP3A activity by clarithromycin during Helicobacter pylori eradication therapy assessed by changes in plasma lansoprazole levels and partial cortisol clearance to 6beta-hydroxycortisol

30 September 2017

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.53

Impairment of CYP3A4 capacity in patients receiving danazol therapy: examination on oxidative cortisol metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.53

Evidence for the validity of cortisol 6 beta-hydroxylation clearance as a new index for in vivo cytochrome P450 3A phenotyping in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.53

Assessment of specificity of eight chemical inhibitors using cDNA-expressed cytochromes P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.53

Evaluation of the protein binding ratio of drugs by a micro-scale ultracentrifugation method

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.53

4beta-hydroxycholesterol as a marker of CYP3A4 inhibition in vivo - effects of itraconazole in man.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481835

Influence of amiodarone on urinary excretion of 6beta-hydroxycortisol in humans

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481835

Cortisol metabolism by human liver in vitro--I. Metabolite identification and inter-individual variability

22 September 2018

1 reference

12 December 2020

Cortisol metabolism in vitro--III. Inhibition of microsomal 6 beta-hydroxylase and cytosolic 4-ene-reductase

1 reference

12 December 2020

St John's Wort: effect on CYP3A4 activity

1 reference

12 December 2020

Biotransformation of tirilazad in human: 2. Effect of ketoconazole on tirilazad clearance and oral bioavailability

1 reference

12 December 2020

Pharmacokinetic study of the interaction between rifampin and delavirdine mesylate

1 reference

12 December 2020

Neither dapsone hydroxylation nor cortisol 6beta-hydroxylation detects the inhibition of CYP3A4 by HIV-1 protease inhibitors

1 reference

12 December 2020

The physiologic significance of 6beta-hydroxycortisol in human corticoid metabolism

1 reference

12 December 2020

Determination of free and total cortisol in plasma and urine by liquid chromatography-tandem mass spectrometry

1 reference

12 December 2020

Identifiers

DOI

10.1038/CLPT.2011.53

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

21490593

1 reference