(Q36354544)

English

Population pharmacokinetic and pharmacodynamic model-based comparability assessment of a recombinant human Epoetin Alfa and the Biosimilar HX575.

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162538%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Population pharmacokinetic and pharmacodynamic model-based comparability assessment of a recombinant human Epoetin Alfa and the Biosimilar HX575 (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162538%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

pharmacokinetics

1 reference

based on heuristic

inferred from title

pharmacodynamics

1 reference

based on heuristic

inferred from title

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162538%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

author name string

Xiaoyu Yan

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162538%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Martin Fink

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162538%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Alexander Berghout

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162538%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Sigrid Balser

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162538%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Wojciech Krzyzanski

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162538%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

language of work or name

1 reference

based on heuristic

inferred from title

publication date

12 December 2011

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162538%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

The Journal of Clinical Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162538%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

52

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162538%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

11

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162538%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1624-1644

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162538%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Interpretation of transit compartments pharmacodynamic models as lifespan based indirect response models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Pharmacodynamics-mediated drug disposition (PDMDD) and precursor pool lifespan model for single dose of romiplostim in healthy subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Evidence of receptor-mediated elimination of erythropoietin by analysis of erythropoietin receptor mRNA expression in bone marrow and erythropoietin clearance during anemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Selection between Michaelis-Menten and target-mediated drug disposition pharmacokinetic models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Bioequivalence tests based on individual estimates using non-compartmental or model-based analyses: evaluation of estimates of sample means and type I error for different designs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Bioequivalence of HX575 (recombinant human epoetin alfa) and a comparator epoetin alfa after multiple intravenous administrations: an open-label randomised controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Pharmacokinetic and pharmacodynamic modeling of pegylated thrombopoietin mimetic peptide (PEG-TPOm) after single intravenous dose administration in healthy subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Bioequivalence of HX575 (recombinant human epoetin alfa) and a comparator epoetin alfa after multiple subcutaneous administrations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Erythropoietins: a common mechanism of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Investigation of the effects of altered receptor binding activity on the clearance of erythropoiesis-stimulating proteins: Nonerythropoietin receptor-mediated pathways may play a major role

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Modeling time variant distributions of cellular lifespans: increases in circulating reticulocyte lifespans following double phlebotomies in sheep

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Basic pharmacodynamic models for agents that alter the lifespan distribution of natural cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Pharmacodynamic analysis of recombinant human erythropoietin effect on reticulocyte production rate and age distribution in healthy subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Use of epoetin and darbepoetin in patients with cancer: 2007 American Society of Hematology/American Society of Clinical Oncology clinical practice guideline update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Diagnosing model diagnostics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Change in erythropoietin pharmacokinetics following hematopoietic transplantation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Development and evaluation of a population pharmacokinetic-pharmacodynamic model of darbepoetin alfa in patients with nonmyeloid malignancies undergoing multicycle chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Preclinical evaluation of Hematide, a novel erythropoiesis stimulating agent, for the treatment of anemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Cellular trafficking and degradation of erythropoietin and novel erythropoiesis stimulating protein (NESP).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Erythropoietin: the story of hypoxia and a finely regulated hematopoietic hormone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Apoptotic mechanisms in the control of erythropoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Oxygen sensing by HIF hydroxylases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Diversity of mechanism-based pharmacodynamic models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Optimizing the use of erythropoietic agents-- pharmacokinetic and pharmacodynamic considerations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

New insights into erythropoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Signal transduction in the erythropoietin receptor system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Cloning and expression of the human erythropoietin gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Erythropoietin retards DNA breakdown and prevents programmed death in erythroid progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Erythropoietin receptor characteristics on primary human erythroid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Purification of human erythropoietin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

30 September 2017

Efficacy prospective study of different frequencies of Epo administration by i.v. and s.c. routes in renal replacement therapy patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

29 June 2018

Cessation of intensive treatment with recombinant human erythropoietin is followed by secondary anemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

29 June 2018

A comparison of the standard approach and the NONMEM approach in the estimation of bioavailability in man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

29 June 2018

Operational models of pharmacological agonism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

29 June 2018

The erythropoietin receptor of rat erythroid progenitor lens. Characterization and affinity cross-linkage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

29 June 2018

Binding of iodinated erythropoietin to rat bone marrow cells under normal and anemic conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

29 June 2018

Dynamics of erythropoietin receptor expression on erythropoietin-responsive murine cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

29 June 2018

The International Standard for Recombinant DNA-derived Erythropoietin: collaborative study of four recombinant DNA-derived erythropoietins and two highly purified human urinary erythropoietins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

29 June 2018

General pharmacokinetic model for drugs exhibiting target-mediated drug disposition

1 reference

https://api.crossref.org/works/10.1177%2F0091270011421911

21 January 2018

Quasi-equilibrium pharmacokinetic model for drugs exhibiting target-mediated drug disposition.

1 reference

https://api.crossref.org/works/10.1177%2F0091270011421911

21 January 2018

Exposure‐Response Modeling of Darbepoetin Alfa in Anemic Patients With Chronic Kidney Disease Not Receiving Dialysis

1 reference

https://api.crossref.org/works/10.1177%2F0091270011421911

21 January 2018

Population pharmacokinetics meta-analysis of recombinant human erythropoietin in healthy subjects.

1 reference

https://api.crossref.org/works/10.1177%2F0091270011421911

21 January 2018

The utility of the population approach applied to bioequivalence in patients: comparison of 2 formulations of cyclosporine

1 reference

https://api.crossref.org/works/10.1177%2F0091270011421911

21 January 2018

Unaltered etanercept pharmacokinetics with concurrent methotrexate in patients with rheumatoid arthritis.

1 reference

https://api.crossref.org/works/10.1177%2F0091270011421911

21 January 2018

Population modeling of filgrastim PK-PD in healthy adults following intravenous and subcutaneous administrations.

1 reference

https://api.crossref.org/works/10.1177%2F0091270011421911

21 January 2018

Pharmacokinetic and pharmacodynamic modeling of recombinant human erythropoietin after multiple subcutaneous doses in healthy subjects.

1 reference

https://api.crossref.org/works/10.1177%2F0091270011421911

21 January 2018

Pharmacokinetic and pharmacodynamic modeling of recombinant human erythropoietin after single and multiple doses in healthy volunteers.

1 reference

https://api.crossref.org/works/10.1177%2F0091270011421911

21 January 2018

Pharmacokinetics and pharmacodynamics of the erythropoietin Mimetibody construct CNTO 528 in healthy subjects

1 reference

https://api.crossref.org/works/10.1177%2F0091270011421911

21 January 2018

Basic pharmacodynamic models for agents that alter production of natural cells.

1 reference

https://api.crossref.org/works/10.1177%2F0091270011421911

21 January 2018

Population cell life span models for effects of drugs following indirect mechanisms of action.

1 reference

https://api.crossref.org/works/10.1177%2F0091270011421911

21 January 2018

Population pharmacokinetics and pharmacodynamics of peptidic erythropoiesis receptor agonist (ERA) in healthy volunteers

1 reference

https://api.crossref.org/works/10.1177%2F0091270011421911

21 January 2018

Target-mediated pharmacokinetic and pharmacodynamic model of recombinant human erythropoietin (rHuEPO).

1 reference

https://api.crossref.org/works/10.1177%2F0091270011421911

21 January 2018

Control of rHuEPO biological activity: the role of carbohydrate.

1 reference

https://api.crossref.org/works/10.1177%2F0091270011421911

21 January 2018

Changes in erythropoietin pharmacokinetics following busulfan-induced bone marrow ablation in sheep: evidence for bone marrow as a major erythropoietin elimination pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483448

22 September 2018

Survival or death of individual proerythroblasts results from differing erythropoietin sensitivities: a mechanism for controlled rates of erythrocyte production

1 reference

https://pubmed.ncbi.nlm.nih.gov/22162538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

rh-erythropoietin stimulates immature reticulocyte release in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/22162538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bioequivalence: individual and population compartmental modeling compared to the noncompartmental approach

1 reference

https://pubmed.ncbi.nlm.nih.gov/22162538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism for the nonlinear pharmacokinetics of erythropoietin in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22162538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of novel erythropoiesis stimulating protein compared with epoetin alfa in dialysis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22162538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the highly variable bioavailability of tiludronate in normal volunteers using population pharmacokinetic methodologies

1 reference

https://pubmed.ncbi.nlm.nih.gov/22162538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of high affinity receptors for erythropoietin on human bone marrow cells and on the human erythroleukemic cell line, HEL

1 reference

https://pubmed.ncbi.nlm.nih.gov/22162538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitation of specific binding of erythropoietin to human erythroid colony-forming cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22162538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant human erythropoietin treatment in pre-dialysis patients. A double-blind placebo-controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/22162538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of recombinant human erythropoietin after SC administration and in long-term IV treatment in patients on maintenance hemodialysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22162538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and effects of recombinant human erythropoietin after intravenous and subcutaneous injections in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/22162538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Application of the NONMEM method to evaluation of the bioavailability of drug products

1 reference

https://pubmed.ncbi.nlm.nih.gov/22162538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacology and economics of recombinant human erythropoietin in end-stage renal disease: the case for subcutaneous administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/22162538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of erythropoietin in genetically anemic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22162538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Precursor-dependent indirect pharmacodynamic response model for tolerance and rebound phenomena

1 reference

https://pubmed.ncbi.nlm.nih.gov/22162538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statistical issues in a modeling approach to assessing bioequivalence or PK similarity with presence of sparsely sampled subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/22162538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of once-weekly epoetin alfa

1 reference

https://pubmed.ncbi.nlm.nih.gov/22162538

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1177/0091270011421911

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162538%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162538%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162538%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

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