(Q36355592)

English

Single-cell genetic analysis of ductal carcinoma in situ and invasive breast cancer reveals enormous tumor heterogeneity yet conserved genomic imbalances and gain of MYC during progression.

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scholarly article

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23062488%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Single-cell genetic analysis of ductal carcinoma in situ and invasive breast cancer reveals enormous tumor heterogeneity yet conserved genomic imbalances and gain of MYC during progression (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23062488%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

ductal carcinoma

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Russell Schwartz

12

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10 March 2020

Kathleen A Calzone

8

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10 March 2020

Alejandro A Schäffer

13

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Alejandro A Schäffer

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10 March 2020

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Kerstin Heselmeyer-Haddad

1

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10 March 2020

Lissa Y Berroa Garcia

2

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10 March 2020

Amanda Bradley

3

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10 March 2020

Clarymar Ortiz-Melendez

4

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10 March 2020

Woei-Jyh Lee

5

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10 March 2020

Rebecca Christensen

6

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10 March 2020

Sheila A Prindiville

7

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10 March 2020

Peter W Soballe

9

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10 March 2020

Yue Hu

10

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10 March 2020

Salim A Chowdhury

11

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10 March 2020

Thomas Ried

14

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10 March 2020

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publication date

8 October 2012

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10 March 2020

The American Journal of Pathology

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10 March 2020

181

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23062488%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23062488%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1807-1822

1 reference

Europe PubMed Central

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10 March 2020

The consequences of chromosomal aneuploidy on the transcriptome of cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Genomic and mutational profiling of ductal carcinomas in situ and matched adjacent invasive breast cancers reveals intra-tumour genetic heterogeneity and clonal selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Is carcinogenesis a form of speciation?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

MYC and metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Global cancer statistics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

AACR centennial series: the biology of cancer metastasis: historical perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

PIK3CA mutations in in situ and invasive breast carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Genomic instability in breast cancer: pathogenesis and clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

The landscape of somatic copy-number alteration across human cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Ductal carcinoma in situ of the breast: a systematic review of incidence, treatment, and outcomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Fluorescence in situ hybridization markers for prediction of cervical lymph node metastases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Detection of genomic amplification of the human telomerase gene TERC, a potential marker for triage of women with HPV-positive, abnormal Pap smears

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Preinvasive breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Genetic disparity between primary tumours, disseminated tumour cells, and manifest metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Blinded by the Light: The Growing Complexity of p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

The gene expression signature of genomic instability in breast cancer is an independent predictor of clinical outcome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Transcriptional control of human p53-regulated genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Molecular mechanisms of erbB2-mediated breast cancer chemoresistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Cyclin D1 down-regulation is essential for DBC2's tumor suppressor function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

p53 in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Combined cDNA array comparative genomic hybridization and serial analysis of gene expression analysis of breast tumor progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Minireview: Cyclin D1: normal and abnormal functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Detection of Genomic Amplification of the Human Telomerase Gene (TERC) in Cytologic Specimens as a Genetic Test for the Diagnosis of Cervical Dysplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Gene expression profiles of human breast cancer progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Molecular markers in ductal carcinoma in situ of the breast.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

DBC2, a candidate for a tumor suppressor gene involved in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

A progression puzzle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

A SAGE (serial analysis of gene expression) view of breast tumor progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Cyclooxygenase-2: a target for the prevention and treatment of breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Untangling the ErbB signalling network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

The ZNF217 gene amplified in breast cancers promotes immortalization of human mammary epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Extensive ductal carcinoma In situ with small foci of invasive ductal carcinoma: evidence of genetic resemblance by CGH.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Intratumoral heterogeneity in breast carcinoma revealed by laser-microdissection and comparative genomic hybridization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Analysis of loss of heterozygosity in 399 premalignant breast lesions at 15 genetic loci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

30 September 2017

Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

29 June 2018

Molecular differences between ductal carcinoma in situ and adjacent invasive breast carcinoma: a multiplex ligation-dependent probe amplification study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

22 September 2018

Homage to Theodor Boveri (1862-1915): Boveri's theory of cancer as a disease of the chromosomes, and the landscape of genomic imbalances in human carcinomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

22 September 2018

Integrated genomic and transcriptomic analysis of ductal carcinoma in situ of the breast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

22 September 2018

Ductal carcinoma in situ and the emergence of diversity during breast cancer evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

22 September 2018

A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

22 September 2018

HER2 status in pure ductal carcinoma in situ and in the intraductal and invasive components of invasive ductal carcinoma determined by fluorescence in situ hybridization and immunohistochemistry.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

22 September 2018

In situ analyses of genome instability in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

22 September 2018

Patterns of chromosomal alterations in breast ductal carcinoma in situ

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

22 September 2018

Association of C-MYC amplification with progression from the in situ to the invasive stage in C-MYC-amplified breast carcinomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

22 September 2018

C-myc oncogene amplification in ductal carcinoma in situ of the breast.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

22 September 2018

Heterogeneous chromosomal aberrations in intraductal breast lesions adjacent to invasive carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483801

22 September 2018

Prognostic significance of nuclear DNA content in mammary adenocarcinomas in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/23062488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative genomic hybridization of formalin-fixed, paraffin-embedded breast tumors reveals different patterns of chromosomal gains and losses in fibroadenomas and diploid and aneuploid carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/23062488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative genomic hybridization of ductal carcinoma in situ of the breast-evidence of multiple genetic pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/23062488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic Differences Between Pure Ductal Carcinoma In Situ of the Breast and that Associated with Invasive Disease: a Calibrated aCGH Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/23062488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic instability and oncogene amplifications in colorectal adenomas predict recurrence and synchronous carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23062488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Responsiveness of adjacent ductal carcinoma in situ and changes in HER2 status after neoadjuvant chemotherapy/trastuzumab treatment in early breast cancer--results from the GeparQuattro study (GBG 40)

1 reference

https://pubmed.ncbi.nlm.nih.gov/23062488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of copy number alterations associated with the progression of DCIS to invasive ductal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23062488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different genetic pathways in the evolution of invasive breast cancer are associated with distinct morphological subtypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23062488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ductal invasive G2 and G3 carcinomas of the breast are the end stages of at least two different lines of genetic evolution

1 reference

https://pubmed.ncbi.nlm.nih.gov/23062488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of chromosomal aneuploidies and gene copy number changes in fine needle aspirates is a specific, sensitive, and objective genetic test for the diagnosis of breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23062488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.AJPATH.2012.07.012

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23062488%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23062488%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23062488%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

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