(Q36356253)

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Leptin stimulates migration and invasion and maintains cancer stem-like properties in ovarian cancer cells: an explanation for poor outcomes in obese women

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scholarly article

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Europe PubMed Central

PMC publication ID

13 August 2017

Leptin stimulates migration and invasion and maintains cancer stem-like properties in ovarian cancer cells: an explanation for poor outcomes in obese women (English)

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Europe PubMed Central

PMC publication ID

13 August 2017

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Sumie Kato

1

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Europe PubMed Central

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13 August 2017

Lorena Abarzua-Catalan

2

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13 August 2017

César Trigo

3

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13 August 2017

Ana Delpiano

4

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13 August 2017

Cristobal Sanhueza

5

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13 August 2017

Karen García

6

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13 August 2017

Carolina Ibañez

7

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13 August 2017

Katherine Hormazábal

8

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13 August 2017

Daniela Diaz

9

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13 August 2017

Jorge Brañes

10

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13 August 2017

Enrique Castellón

11

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13 August 2017

Erasmo Bravo

12

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13 August 2017

Gareth Owen

13

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13 August 2017

Mauricio A Cuello

14

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13 August 2017

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publication date

22 May 2015

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13 August 2017

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13 August 2017

6

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13 August 2017

25

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Europe PubMed Central

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13 August 2017

21100-21119

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Europe PubMed Central

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13 August 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4673253/fullTextXML

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Metformin inhibits thyroid cancer cell growth, migration, and EMT through the mTOR pathway

1 reference

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1 reference

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Estrogen biosynthesis and action in ovarian cancer

1 reference

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30 September 2017

Obesity increases tumor aggressiveness in a genetically engineered mouse model of serous ovarian cancer.

1 reference

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30 September 2017

Expression of leptin receptor in endometrial biopsies of endometrial and ovarian cancer patients

1 reference

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Obesity is associated with worse overall survival in women with low-grade papillary serous epithelial ovarian cancer

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Leptin receptor maintains cancer stem-like properties in triple negative breast cancer cells.

1 reference

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30 September 2017

Metformin, at concentrations corresponding to the treatment of diabetes, potentiates the cytotoxic effects of carboplatin in cultures of ovarian cancer cells

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30 September 2017

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30 September 2017

Leptin and cancer: Pathogenesis and modulation.

1 reference

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30 September 2017

Adipose tissue and adipocytes support tumorigenesis and metastasis

1 reference

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30 September 2017

Involvement of adipokines, AMPK, PI3K and the PPAR signaling pathways in ovarian follicle development and cancer

1 reference

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Obesity and risk of ovarian cancer subtypes: evidence from the Ovarian Cancer Association Consortium

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On the origin and destination of cancer stem cells: a conceptual evaluation

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30 September 2017

Leptin stimulates ovarian cancer cell growth and inhibits apoptosis by increasing cyclin D1 and Mcl-1 expression via the activation of the MEK/ERK1/2 and PI3K/Akt signaling pathways

1 reference

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30 September 2017

Leptin stimulation of cell cycle and inhibition of apoptosis gene and protein expression in OVCAR-3 ovarian cancer cells

1 reference

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Profiling of cytokines in human epithelial ovarian cancer ascites.

1 reference

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Obesity and ovarian cancer survival: a systematic review and meta-analysis

1 reference

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Ovarian cancer and body size: individual participant meta-analysis including 25,157 women with ovarian cancer from 47 epidemiological studies

1 reference

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The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

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Minireview: human ovarian cancer: biology, current management, and paths to personalizing therapy

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Inflammation and ovarian cancer

1 reference

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30 September 2017

Leptin-induced epithelial-mesenchymal transition in breast cancer cells requires β-catenin activation via Akt/GSK3- and MTA1/Wnt1 protein-dependent pathways

1 reference

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Pluripotency factor-mediated expression of the leptin receptor (OB-R) links obesity to oncogenesis through tumor-initiating stem cells

1 reference

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Interleukin-6 as a therapeutic target in human ovarian cancer

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Comparison of candidate serologic markers for type I and type II ovarian cancer

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Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer--shifting the paradigm

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Leptin receptor signaling: pathways to leptin resistance

1 reference

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Global cancer statistics

1 reference

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Ovarian cancer development and metastasis

1 reference

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Leptin stimulates the migration of colon carcinoma cells by multiple signaling pathways

1 reference

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Overexpression of leptin receptor predicts an unfavorable outcome in Middle Eastern ovarian cancer.

1 reference

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1 reference

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Metastasis mechanisms

1 reference

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Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial-mesenchymal transition in ovarian carcinomas.

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Expression of leptin long-form receptor mRNA in luteinized granulosa cells of obese women with polycystic ovary syndrome

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Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells

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Convergent trafficking pattern of leptin after endocytosis mediated by ObRa-ObRd

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TRAIL mediates apoptosis in cancerous but not normal primary cultured cells of the human reproductive tract

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30 September 2017

Regulation of cancer cell motility through actin reorganization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673253

30 September 2017

Expression of leptin receptors and potential effects of leptin on the cell growth and activation of mitogen-activated protein kinases in ovarian cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673253

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1 reference

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1 reference

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Rho proteins: linking signaling with membrane trafficking

1 reference

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30 September 2017

Obesity-associated adipokines correlate with survival in epithelial ovarian cancer

1 reference

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Plasma leptin levels: interaction of obesity with a common variant of insulin receptor substrate-1.

1 reference

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22 September 2018

[Association between obesity and ovarian cancer]

1 reference

https://pubmed.ncbi.nlm.nih.gov/26053184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional properties of leptin receptor isoforms: internalization and degradation of leptin and ligand-induced receptor downregulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/26053184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.18632/ONCOTARGET.4228

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ResearchGate publication ID

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