(Q36363960)

13 August 2017

Lysosomal Cholesterol Accumulation Sensitizes To Acetaminophen Hepatotoxicity by Impairing Mitophagy (English)

1 reference

13 August 2017

1 reference

1 reference

2

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9 June 2020

Laura Martínez

6

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9 June 2020

José C Fernández-Checa

11

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9 June 2020

author name string

Anna Baulies

1

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9 June 2020

Susana Núñez

3

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9 June 2020

Cristina Alarcón-Vila

5

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9 June 2020

Jo Suda

7

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9 June 2020

Maria D Ybanez

8

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9 June 2020

Neil Kaplowitz

9

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9 June 2020

Carmen García-Ruiz

10

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9 June 2020

Sandra Torres

4

1 reference

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9 June 2020

language of work or name

English

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publication date

11 December 2015

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13 August 2017

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9 June 2020

volume

5

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9 June 2020

page(s)

18017

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Creative Commons Attribution 4.0 International

9 June 2020

copyright license

start time

11 December 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

The emerging role of acid sphingomyelinase in autophagy

1 reference

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Acid sphingomyelinase-ceramide system in steatohepatitis: a novel target regulating multiple pathways

30 September 2017

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High sphingomyelin levels induce lysosomal damage and autophagy dysfunction in Niemann Pick disease type A.

30 September 2017

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Control of autophagy maturation by acid sphingomyelinase in mouse coronary arterial smooth muscle cells: protective role in atherosclerosis

30 September 2017

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Impaired autophagy in the lipid-storage disorder Niemann-Pick type C1 disease

30 September 2017

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Zonated induction of autophagy and mitochondrial spheroids limits acetaminophen-induced necrosis in the liver

30 September 2017

1 reference

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Protection of a ceramide synthase 2 null mouse from drug-induced liver injury: role of gap junction dysfunction and connexin 32 mislocalization

30 September 2017

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Acid sphingomyelinase–ceramide system mediates effects of antidepressant drugs

30 September 2017

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The ubiquitin ligase Mul1 induces mitophagy in skeletal muscle in response to muscle-wasting stimuli

30 September 2017

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Mitophagy: mechanisms, pathophysiological roles, and analysis

30 September 2017

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Lysosomal instability and cathepsin B release during acetaminophen hepatotoxicity.

30 September 2017

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Cathepsin B overexpression due to acid sphingomyelinase ablation promotes liver fibrosis in Niemann-Pick disease

30 September 2017

1 reference

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Activation of autophagy protects against acetaminophen-induced hepatotoxicity

30 September 2017

1 reference

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A sensitive and quantitative technique for detecting autophagic events based on lysosomal delivery

30 September 2017

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SIRT3-dependent deacetylation exacerbates acetaminophen hepatotoxicity

30 September 2017

1 reference

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Attenuation of the lysosomal death pathway by lysosomal cholesterol accumulation

30 September 2017

1 reference

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Nonesterified cholesterol content of lysosomes modulates susceptibility to oxidant-induced permeabilization

30 September 2017

1 reference

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Eaten alive: a history of macroautophagy

30 September 2017

1 reference

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Lysosomal iron mobilization and induction of the mitochondrial permeability transition in acetaminophen-induced toxicity to mouse hepatocytes.

30 September 2017

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Acid sphingomyelinase, cell membranes and human disease: lessons from Niemann-Pick disease

30 September 2017

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Dynamics and diversity in autophagy mechanisms: lessons from yeast

30 September 2017

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Sterol regulators of cholesterol homeostasis and beyond: the oxysterol hypothesis revisited and revised

30 September 2017

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Regulation of H(2)O(2)-induced necrosis by PKC and AMP-activated kinase signaling in primary cultured hepatocytes

30 September 2017

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Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injury

30 September 2017

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Role of cholesterol and lipid organization in disease

30 September 2017

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Intracellular signaling mechanisms of acetaminophen-induced liver cell death

30 September 2017

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Acetaminophen and the U.S. Acute Liver Failure Study Group: lowering the risks of hepatic failure

30 September 2017

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Defective TNF-alpha-mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice

30 September 2017

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Sphingomyelin-cholesterol interactions in biological and model membranes

30 September 2017

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Interactions between metabolism and intracellular distribution of cholesterol and sphingomyelin

30 September 2017

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Cholesterol movement in Niemann-Pick type C cells and in cells treated with amphiphiles

30 September 2017

1 reference

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Sphingomyelin depletion in cultured cells blocks proteolysis of sterol regulatory element binding proteins at site 1.

30 September 2017

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Acid sphingomyelinase deficient mice: a model of types A and B Niemann-Pick disease

30 September 2017

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ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis

30 September 2017

1 reference

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Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes

28 June 2018

1 reference

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Nitrotyrosine-protein adducts in hepatic centrilobular areas following toxic doses of acetaminophen in mice

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4676017

Feeding S-adenosyl-L-methionine attenuates both ethanol-induced depletion of mitochondrial glutathione and mitochondrial dysfunction in periportal and perivenous rat hepatocytes

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4676017

Potentiation by Previous Drug Therapy of Hepatotoxicity following Paracetamol Overdosage

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4676017

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4676017

Co-medications that modulate liver injury and repair influence clinical outcome of acetaminophen-associated liver injury

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4676017

c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4676017

Distribution and dynamics of Lamp1-containing endocytic organelles in fibroblasts deficient in BLOC-3.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4676017

Loss of amitriptyline analgesia in alpha 2A-adrenoceptor deficient mice

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4676017

Mechanisms for sensitization to TNF-induced apoptosis by acute glutathione depletion in murine hepatocytes

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4676017

Glucosylceramide modulates membrane traffic along the endocytic pathway

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4676017

Acid sphingomyelinase-deficient macrophages have defective cholesterol trafficking and efflux

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4676017

22 September 2018

1 reference

https://api.crossref.org/works/10.1038%2FSREP18017

Acetaminophen-induced hepatic injury: protective role of glutathione in man and rationale for therapy.

21 January 2018

1 reference

12 December 2020

Acetaminophen-induced inhibition of hepatic mitochondrial respiration in mice

1 reference

12 December 2020

Glutathione disulfide formation and oxidant stress during acetaminophen-induced hepatotoxicity in mice in vivo: the protective effect of allopurinol

1 reference

12 December 2020

Bile acid and sterol solubilization in 2-hydroxypropyl-beta-cyclodextrin

1 reference

12 December 2020

Role of CYP2E1 in the hepatotoxicity of acetaminophen

1 reference

12 December 2020

Lysenin, a novel sphingomyelin-specific binding protein

1 reference

12 December 2020

Loss of autophagy promotes murine acetaminophen hepatotoxicity

1 reference

12 December 2020

Identifiers

DOI

10.1038/SREP18017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26657973%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26657973%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

PubMed publication ID

26657973

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26657973%20AND%20SRC:MED&resulttype=core&format=json