(Q36364238)

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Activation of the unfolded protein response by 2-deoxy-D-glucose inhibits Kaposi's sarcoma-associated herpesvirus replication and gene expression

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scholarly article

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Europe PubMed Central

13 August 2017

Activation of the unfolded protein response by 2-deoxy-D-glucose inhibits Kaposi's sarcoma-associated herpesvirus replication and gene expression (English)

1 reference

Europe PubMed Central

13 August 2017

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Enrique A Mesri

6

object named as

Enrique A Mesri

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Europe PubMed Central

13 August 2017

author name string

Howard J Leung

1

1 reference

Europe PubMed Central

13 August 2017

Elda M Duran

2

1 reference

Europe PubMed Central

13 August 2017

Metin Kurtoglu

3

1 reference

Europe PubMed Central

13 August 2017

Samita Andreansky

4

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Europe PubMed Central

13 August 2017

Theodore J Lampidis

5

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Europe PubMed Central

13 August 2017

language of work or name

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publication date

27 August 2012

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Europe PubMed Central

13 August 2017

Antimicrobial Agents and Chemotherapy

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Europe PubMed Central

13 August 2017

56

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Europe PubMed Central

13 August 2017

11

1 reference

Europe PubMed Central

13 August 2017

5794-5803

1 reference

Europe PubMed Central

13 August 2017

HCV causes chronic endoplasmic reticulum stress leading to adaptation and interference with the unfolded protein response

1 reference

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30 September 2017

Generation of a doxycycline-inducible KSHV producer cell line of endothelial origin: maintenance of tight latency with efficient reactivation upon induction

1 reference

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30 September 2017

Role of the host cell's unfolded protein response in arenavirus infection.

1 reference

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30 September 2017

Antiangiogenic activity of 2-deoxy-D-glucose

1 reference

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30 September 2017

X-box binding protein 1 induces the expression of the lytic cycle transactivator of Kaposi's sarcoma-associated herpesvirus but not Epstein-Barr virus in co-infected primary effusion lymphoma

1 reference

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30 September 2017

Kaposi's sarcoma and its associated herpesvirus

1 reference

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30 September 2017

Targeting tumor metabolism with 2-deoxyglucose in patients with castrate-resistant prostate cancer and advanced malignancies

1 reference

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30 September 2017

2-Deoxy-D-glucose activates autophagy via endoplasmic reticulum stress rather than ATP depletion

1 reference

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30 September 2017

Induction of the Warburg effect by Kaposi's sarcoma herpesvirus is required for the maintenance of latently infected endothelial cells

1 reference

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30 September 2017

KSHV and the pathogenesis of Kaposi sarcoma: listening to human biology and medicine

1 reference

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30 September 2017

Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells

1 reference

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30 September 2017

2-Deoxy-D-glucose enhances TRAIL-induced apoptosis in human melanoma cells through XBP-1-mediated up-regulation of TRAIL-R2

1 reference

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30 September 2017

Kaposi's sarcoma-associated herpesvirus glycoproteins B and K8.1 regulate virion egress and synthesis of vascular endothelial growth factor and viral interleukin-6 in BCBL-1 cells

1 reference

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30 September 2017

Early events in Kaposi's sarcoma-associated herpesvirus infection of target cells

1 reference

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30 September 2017

HIV-associated lymphomas and gamma-herpesviruses.

1 reference

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30 September 2017

Ritonavir induces endoplasmic reticulum stress and sensitizes sarcoma cells toward bortezomib-induced apoptosis

1 reference

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30 September 2017

Intrinsically lower AKT, mammalian target of rapamycin, and hypoxia-inducible factor activity correlates with increased sensitivity to 2-deoxy-D-glucose under hypoxia in lung cancer cell lines

1 reference

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30 September 2017

KSHV infection and the pathogenesis of Kaposi's sarcoma

1 reference

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30 September 2017

Under normoxia, 2-deoxy-D-glucose elicits cell death in select tumor types not by inhibition of glycolysis but by interfering with N-linked glycosylation

1 reference

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30 September 2017

Targeted therapy for Kaposi's sarcoma and Kaposi's sarcoma-associated herpesvirus.

1 reference

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30 September 2017

Differential toxic mechanisms of 2-deoxy-D-glucose versus 2-fluorodeoxy-D-glucose in hypoxic and normoxic tumor cells

1 reference

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30 September 2017

B cell terminal differentiation factor XBP-1 induces reactivation of Kaposi's sarcoma-associated herpesvirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486618

30 September 2017

Incidence of cancers in people with HIV/AIDS compared with immunosuppressed transplant recipients: a meta-analysis

1 reference

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30 September 2017

Hypoxia-inducible factor-1 confers resistance to the glycolytic inhibitor 2-deoxy-D-glucose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486618

30 September 2017

The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486618

30 September 2017

Viruses, endoplasmic reticulum stress, and interferon responses

1 reference

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30 September 2017

The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor as a therapeutic target for the treatment of Kaposi's sarcoma.

1 reference

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30 September 2017

Production of infectious human cytomegalovirus virions is inhibited by drugs that disrupt calcium homeostasis in the endoplasmic reticulum

1 reference

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30 September 2017

Human cytomegalovirus infection activates and regulates the unfolded protein response

1 reference

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30 September 2017

Human cytomegalovirus protein US11 provokes an unfolded protein response that may facilitate the degradation of class I major histocompatibility complex products

1 reference

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30 September 2017

Herpes simplex virus 1 infection activates the endoplasmic reticulum resident kinase PERK and mediates eIF-2alpha dephosphorylation by the gamma(1)34.5 protein

1 reference

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30 September 2017

Autoregulation of DNA binding and protein stability of Kaposi's sarcoma-associated herpesvirus ORF50 protein

1 reference

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30 September 2017

Use of the red fluorescent protein as a marker of Kaposi's sarcoma-associated herpesvirus lytic gene expression

1 reference

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30 September 2017

A trip to the ER: coping with stress

1 reference

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30 September 2017

Inefficient establishment of KSHV latency suggests an additional role for continued lytic replication in Kaposi sarcoma pathogenesis.

1 reference

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30 September 2017

Evasion of cellular antiviral responses by human cytomegalovirus TRS1 and IRS1

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30 September 2017

Use of HIV protease inhibitors to block Kaposi's sarcoma and tumour growth

1 reference

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Kaposi's sarcoma-associated herpesvirus-infected primary effusion lymphoma has a plasma cell gene expression profile

1 reference

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Comparative study of regulation of RTA-responsive genes in Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8.

1 reference

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30 September 2017

Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1

1 reference

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30 September 2017

Natural history of murine -herpesvirus infection

1 reference

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30 September 2017

Regulated translation initiation controls stress-induced gene expression in mammalian cells

1 reference

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30 September 2017

Auto-activation of the rta gene of human herpesvirus-8/Kaposi's sarcoma-associated herpesvirus

1 reference

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Viruses in human cancers

1 reference

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Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

1 reference

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30 September 2017

Kinetics of Kaposi's sarcoma-associated herpesvirus gene expression

1 reference

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30 September 2017

The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-

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30 September 2017

Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma

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30 September 2017

Viral glycoprotein metabolism as a target for antiviral substances

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30 September 2017

The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins

1 reference

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Finding a Panacea among combination cancer therapies.

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30 September 2017

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28 June 2018

In vivo-restricted and reversible malignancy induced by human herpesvirus-8 KSHV: a cell and animal model of virally induced Kaposi's sarcoma.

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28 June 2018

Maintenance of endoplasmic reticulum (ER) homeostasis in herpes simplex virus type 1-infected cells through the association of a viral glycoprotein with PERK, a cellular ER stress sensor.

1 reference

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28 June 2018

G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator

1 reference

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28 June 2018

KSHV ORF K9 (vIRF) is an oncogene which inhibits the interferon signaling pathway

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28 June 2018

Anti-herpesvirus treatment and risk of Kaposi's sarcoma in HIV infection. Royal Free/Chelsea and Westminster Hospitals Collaborative Group.

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28 June 2018

Characterization of a human Kaposi's sarcoma cell line that induces angiogenic tumors in animals

1 reference

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28 June 2018

Effects of 2-deoxy-D-glucose on herpes simplex virus replication

1 reference

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28 June 2018

Increased hypoxia following vessel targeting in a murine model of retinoblastoma.

1 reference

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22 September 2018

Expression of LKB1 tumor suppressor in non-small cell lung cancer determines sensitivity to 2-deoxyglucose

1 reference

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22 September 2018

2-deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo

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22 September 2018

Kaposi's sarcoma associated herpesvirus G protein-coupled receptor immortalizes human endothelial cells by activation of the VEGF receptor-2/ KDR.

1 reference

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22 September 2018

Identifiers

10.1128/AAC.01126-12

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

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