(Q36365141)

13 August 2017

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title

Pharmacokinetic-pharmacodynamic modelling: history and perspectives (English)

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13 August 2017

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Chantal Csajka

1

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author name string

Davide Verotta

series ordinal

2

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13 August 2017

publication date

11 January 2006

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Journal of Pharmacokinetics and Pharmacodynamics

13 August 2017

published in

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13 August 2017

volume

33

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13 August 2017

issue

3

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13 August 2017

page(s)

227-279

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https://scigraph.springernature.com/pub.10.1007/s10928-005-9002-0

13 August 2017

exact match

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12 December 2020

Modeling plasma virus concentration during primary HIV infection

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12 December 2020

RELATIONSHIP BETWEEN ELIMINATION RATE OF DRUGS AND RATE OF DECLINE OF THEIR PHARMACOLOGIC EFFECTS

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Transit compartments versus gamma distribution function to model signal transduction processes in pharmacodynamics

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12 December 2020

Virus dynamics and drug therapy

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Apparent Potentiating Effect of a Second Dose of Drug

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12 December 2020

The steroid and thyroid hormone receptor superfamily

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12 December 2020

Pharmacokinetics of digoxin: Relationship between response intensity and predicted compartmental drug levels in man

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Pharmacodynamics of Chemotherapeutic Effects: Dose-Time-Response Relationships for Phase-Nonspecific Agents

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Mechanism-based pharmacodynamic modeling

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12 December 2020

Kinetics of pharmacologic response I. Proposed relationships between response and drug concentration in the intact animal and man

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Concepts, properties, and applications of linear systems to describe distribution, identify input, and control endogenous substances and drugs in biological systems.

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Pharmacokinetics and pharmacodynamics of three different prednisolone prodrugs: effect on circulating lymphocyte subsets and function

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Simultaneous modeling of pharmacokinetics and pharmacodynamics with nonparametric kinetic and dynamic models

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12 December 2020

Identification of nonlinear biological systems using Laguerre expansions of kernels.

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12 December 2020

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12 December 2020

Non-linear dynamics models characterizing long-term virological data from AIDS clinical trials

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12 December 2020

Evaluation of a computer-assisted method for individualized anticoagulation: retrospective and prospective studies with a pharmacodynamic model

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12 December 2020

Theoretical relationship between dose, elimination rate, and duration of pharmacologic effect of drugs

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12 December 2020

Comparison of four basic models of indirect pharmacodynamic responses

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12 December 2020

Concepts and usefulness of pharmacokinetic-pharmacodynamic modelling.

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12 December 2020

Pharmacodynamic modeling of chemotherapeutic effects: application of a transit compartment model to characterize methotrexate effects in vitro

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12 December 2020

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12 December 2020

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Mechanism-based pharmacokinetic-pharmacodynamic modeling of the effects of N6-cyclopentyladenosine analogs on heart rate in rat: estimation of in vivo operational affinity and efficacy at adenosine A1 receptors.

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12 December 2020

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12 December 2020

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12 December 2020

Simultaneous modeling of pharmacokinetics and pharmacodynamics: an improved algorithm

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Multiple-dose kinetics of oral anticoagulants: methods of analysis and optimized dosing.

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12 December 2020

Pharmacodynamic model for acute tolerance development to the electroencephalographic effects of alfentanil in the rat.

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12 December 2020

A set-point model with oscillatory behavior predicts the time course of 8-OH-DPAT-induced hypothermia

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12 December 2020

Kinetics of pharmacologic effects

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12 December 2020

Testing computer-controlled infusion pumps by simulation

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12 December 2020

Multiexponential, multicompartmental, and noncompartmental modeling. I. Methodological limitations and physiological interpretations

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12 December 2020

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12 December 2020

Computer-aided long-term anticoagulation therapy

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12 December 2020

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12 December 2020

Modelling of individual pharmacokinetics for computer-aided drug dosage

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Diversity of mechanism-based pharmacodynamic models

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Characterization of the pharmacodynamic interaction between parent drug and active metabolite in vivo: midazolam and alpha-OH-midazolam.

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12 December 2020

Semiparametric models for antagonistic drug interactions

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12 December 2020

A general conceptual model for non-steady state pharmacokinetic/pharmacodynamic data

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12 December 2020

The impact of arteriovenous concentration differences on pharmacodynamic parameter estimates.

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12 December 2020

A comparison study of models and fitting procedures for biphasic viral dynamics in HIV-1 infected patients treated with antiviral therapies.

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12 December 2020

Coexistence and competition in HIV infections

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12 December 2020

Modeling a bivariate control system: LH and testosterone response to the GnRH antagonist antide

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12 December 2020

Mathematical model for in vivo pharmacodynamics integrating fluctuation of the response: application to the prolactin suppressant effect of the dopaminomimetic drug DCN 203-922.

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12 December 2020

Relation between morphine pharmacokinetics and analgesia

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12 December 2020

10.1007/S10928-005-9002-0

Identifiers

DOI

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13 August 2017

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