(Q36365670)

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Bcl-XL displays restricted distribution during T cell development and inhibits multiple forms of apoptosis but not clonal deletion in transgenic mice

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Bcl-XL displays restricted distribution during T cell development and inhibits multiple forms of apoptosis but not clonal deletion in transgenic mice (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

apoptotic process

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Gabriel Núñez

3

object named as

G Núñez

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

author name string

D A Grillot

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

R Merino

2

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Europe PubMed Central

PMC publication ID

13 August 2017

language of work or name

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publication date

1 December 1995

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Journal of Experimental Medicine

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

182

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Europe PubMed Central

PMC publication ID

13 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1973-1983

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Essential genes that regulate apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

p53 is required for radiation-induced apoptosis in mouse thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Developmental regulation of the Bcl-2 protein and susceptibility to cell death in B lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Signal transduction by lymphocyte antigen receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Negative selection of lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Positive selection of lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

T cell receptor antagonist peptides induce positive selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Immature thymocytes become sensitive to calcium-mediated apoptosis with the onset of CD8, CD4, and the T cell receptor expression: a role for bcl-2?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Positive and negative selection of T cells in T-cell receptor transgenic mice expressing a bcl-2 transgene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Molecular regulation of apoptosis: genetic controls on cell death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Bcl-2 expression during T-cell development: early loss and late return occur at specific stages of commitment to differentiation and survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Bcl-2 and Bcl-x: regulatory switches for lymphoid death and survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Bclx regulates the survival of double-positive thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

bcl-xLx is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

T-cell receptor V beta use predicts reactivity and tolerance to Mlsa-encoded antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

N-myc transgene promotes B lymphoid proliferation, elicits lymphomas and reveals cross-regulation with c-myc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Elimination of CD8+ thymocytes in transgenic mice expressing an anti-Lyt2.2 immunoglobulin heavy chain gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

A third T-cell receptor beta-chain variable region gene encodes reactivity to Mls-1a gene products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

An analysis of T-cell receptor variable region gene expression in major histocompatibility complex disparate mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Mechanisms and Functions of Cell Death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Inhibition of thymocyte apoptosis and negative antigenic selection in bcl-2 transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

The development of functionally responsive T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

Cloning and molecular characterization of mouse bcl-x in B and T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

30 September 2017

BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

28 June 2018

Immunohistochemical analysis of in vivo patterns of Bcl-X expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

28 June 2018

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

28 June 2018

Superantigens interact with MHC class II molecules outside of the antigen groove.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

28 June 2018

Expression of the bcl-2 oncogene protein is not specific for the 14;18 chromosomal translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

28 June 2018

Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

28 June 2018

Clonal deletion of immature CD4+8+ thymocytes in suspension culture by extrathymic antigen-presenting cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

28 June 2018

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

28 June 2018

In vivo administration of monoclonal antibodies to the CD3 T cell receptor complex induces cell death (apoptosis) in immature thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

28 June 2018

Characterization of a rat monoclonal antibody specific for a determinant encoded by the V beta 7 gene segment. Depletion of V beta 7+ T cells in mice with Mls-1a haplotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

28 June 2018

Thymocyte apoptosis induced by p53-dependent and independent pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

22 September 2018

Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

22 September 2018

Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

22 September 2018

Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192263

22 September 2018

CD4+CD8+ thymocytes are susceptible to DNA fragmentation induced by phorbol ester, calcium ionophore and anti-CD3 antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/7500043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

bcl-2 proto-oncogene expression during human T cell development. Evidence for biphasic regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7500043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/7500043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Vβ-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletion in neonatal mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7500043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Bcl-2 family of proteins: regulators of cell death and survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/7500043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points

1 reference

https://pubmed.ncbi.nlm.nih.gov/7500043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-4 protects double-negative and CD4 single-positive thymocytes from dexamethasone-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/7500043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7500043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the Bcl-2 protein in murine and human thymocytes and in peripheral T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7500043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-cell apoptosis detected in situ during positive and negative selection in the thymus

1 reference

https://pubmed.ncbi.nlm.nih.gov/7500043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cell tolerance by clonal elimination in the thymus

1 reference

https://pubmed.ncbi.nlm.nih.gov/7500043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

1 reference

https://pubmed.ncbi.nlm.nih.gov/7500043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.182.6.1973

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ResearchGate publication ID

0 references

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