(Q36371192)

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Dysregulation of fragile × mental retardation protein and metabotropic glutamate receptor 5 in superior frontal cortex of individuals with autism: a postmortem brain study

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scholarly article

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Europe PubMed Central

PMC publication ID

13 August 2017

Dysregulation of fragile × mental retardation protein and metabotropic glutamate receptor 5 in superior frontal cortex of individuals with autism: a postmortem brain study (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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author name string

S Hossein Fatemi

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Timothy D Folsom

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

publication date

6 May 2011

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Molecular Autism

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Metabotropic glutamate receptor 5 upregulation in children with autism is associated with underexpression of both Fragile X mental retardation protein and GABAA receptor beta 3 in adults with autism

1 reference

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30 September 2017

The role of fragile X mental retardation protein in major mental disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Low stress reactivity and neuroendocrine factors in the BTBR T+tf/J mouse model of autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Evidence of reactive astrocytes but not peripheral immune system activation in a mouse model of Fragile X syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Roles of fragile X mental retardation protein in dopaminergic stimulation-induced synapse-associated protein synthesis and subsequent alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-4-propionate (AMPA) receptor internalization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Anatomical phenotyping in a mouse model of fragile X syndrome with magnetic resonance imaging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

The developmental roles of FMRP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

mRNA and protein levels for GABAAalpha4, alpha5, beta1 and GABABR1 receptors are altered in brains from subjects with autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Fragile X mental retardation protein in learning-related synaptic plasticity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Repetitive self-grooming behavior in the BTBR mouse model of autism is blocked by the mGluR5 antagonist MPEP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Treatments for fragile X syndrome: a closer look at the data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Norbin is an endogenous regulator of metabotropic glutamate receptor 5 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Fragile X mental retardation protein control of neuronal mRNA metabolism: Insights into mRNA stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

A pilot open label, single dose trial of fenobam in adults with fragile X syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Expression of GABA(B) receptors is altered in brains of subjects with autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

GABA(A) receptor downregulation in brains of subjects with autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Decreased nociceptive sensitization in mice lacking the fragile X mental retardation protein: role of mGluR1/5 and mTOR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Correction of fragile X syndrome in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Neuroanatomy of fragile X syndrome is associated with aberrant behavior and the fragile X mental retardation protein (FMRP).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

RNA regulons: coordination of post-transcriptional events

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Epigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Neuroglial activation and neuroinflammation in the brain of patients with autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

The mGluR theory of fragile X mental retardation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Genetic evidence for the bidirectional modulation of synaptic plasticity in the prefrontal cortex by D1 receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Homologous sites of GABA(A) receptor alpha(1), beta(3) and gamma(2) subunits are important for assembly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Chromosomal abnormalities in a clinic sample of individuals with autistic disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: a quantitative examination.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Alternative splicing of exon 14 determines nuclear or cytoplasmic localisation of fmr1 protein isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

30 September 2017

Open-label treatment trial of lithium to target the underlying defect in fragile X syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

28 June 2018

Multiple distinct subunits of the gamma-aminobutyric acid-A receptor protein show different ligand-binding affinities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

28 June 2018

A sensitive ELISA for glial fibrillary acidic protein: application in CSF of children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

28 June 2018

Autistic behavior in children with fragile X syndrome: prevalence, stability, and the impact of FMRP.

1 reference

https://api.crossref.org/works/10.1186%2F2040-2392-2-6

21 January 2018

Autistic behavior in young boys with fragile X syndrome

1 reference

https://api.crossref.org/works/10.1186%2F2040-2392-2-6

21 January 2018

Social behavior profile in young males with fragile X syndrome: characteristics and specificity.

1 reference

https://api.crossref.org/works/10.1186%2F2040-2392-2-6

21 January 2018

Linguistic and cognitive functioning and autism symptoms in young children with fragile X syndrome

1 reference

https://api.crossref.org/works/10.1186%2F2040-2392-2-6

21 January 2018

Outcomes of genetic evaluation in children with pervasive developmental disorder

1 reference

https://api.crossref.org/works/10.1186%2F2040-2392-2-6

21 January 2018

Autism spectrum disorder in fragile X syndrome: communication, social interaction, and specific behaviors.

1 reference

https://api.crossref.org/works/10.1186%2F2040-2392-2-6

21 January 2018

Fragile X mental retardation protein induces synapse loss through acute postsynaptic translational regulation.

1 reference

https://api.crossref.org/works/10.1186%2F2040-2392-2-6

21 January 2018

Decreased GABA(A) receptor expression in the seizure-prone fragile X mouse.

1 reference

https://api.crossref.org/works/10.1186%2F2040-2392-2-6

21 January 2018

Decreased expression of the GABAA receptor in fragile X syndrome

1 reference

https://api.crossref.org/works/10.1186%2F2040-2392-2-6

21 January 2018

Expression profiling suggests underexpression of the GABA(A) receptor subunit delta in the fragile X knockout mouse model

1 reference

https://api.crossref.org/works/10.1186%2F2040-2392-2-6

21 January 2018

Functional brain activation during cognition is related to FMR1 gene expression.

1 reference

https://api.crossref.org/works/10.1186%2F2040-2392-2-6

21 January 2018

Fronto-striatal dysfunction and potential compensatory mechanisms in male adolescents with fragile X syndrome

1 reference

https://api.crossref.org/works/10.1186%2F2040-2392-2-6

21 January 2018

Functional brain activation during arithmetic processing in females with fragile X Syndrome is related to FMR1 protein expression

1 reference

https://api.crossref.org/works/10.1186%2F2040-2392-2-6

21 January 2018

Dopamine and working memory mechanisms in prefrontal cortex

1 reference

https://api.crossref.org/works/10.1186%2F2040-2392-2-6

21 January 2018

FMRP acts as a key messenger for dopamine modulation in the forebrain

1 reference

https://api.crossref.org/works/10.1186%2F2040-2392-2-6

21 January 2018

Glial fibrillary acidic protein is elevated in superior frontal, parietal and cerebellar cortices of autistic subjects

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https://api.crossref.org/works/10.1186%2F2040-2392-2-6

21 January 2018

Glial fibrillary acidic protein in the cerebrospinal fluid of children with autism and other neuropsychiatric disorders

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https://api.crossref.org/works/10.1186%2F2040-2392-2-6

21 January 2018

Developmental expression of FMRP in the astrocyte lineage: implications for fragile X syndrome.

1 reference

https://api.crossref.org/works/10.1186%2F2040-2392-2-6

21 January 2018

Involvement and therapeutic potential of the GABAergic system in the fragile X syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

21 September 2018

Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

21 September 2018

Brain morphometry volume in autistic spectrum disorder: a magnetic resonance imaging study of adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

21 September 2018

Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

21 September 2018

Early development, temperament, and functional impairment in autism and fragile X syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488976

21 September 2018

Cardiovascular indices of physiological arousal in boys with fragile X syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/21548960

12 December 2020

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10.1186/2040-2392-2-6

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Europe PubMed Central

PMC publication ID

13 August 2017

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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