(Q36375280)

13 August 2017

Somatic mutation and light chain rearrangement generate autoimmunity in anti-single-stranded DNA transgenic MRL/lpr mice (English)

1 reference

13 August 2017

F Brard

1

1 reference

13 August 2017

M Shannon

2

1 reference

13 August 2017

E L Prak

3

1 reference

13 August 2017

S Litwin

4

1 reference

13 August 2017

M Weigert

5

1 reference

13 August 2017

language of work or name

English

0 references

publication date

1 September 1999

1 reference

Journal of Experimental Medicine

13 August 2017

1 reference

13 August 2017

190

1 reference

13 August 2017

5

1 reference

13 August 2017

691-704

1 reference

Regulation of anti-DNA B cells in recombination-activating gene-deficient mice

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Efficient peripheral clonal elimination of B lymphocytes in MRL/lpr mice bearing autoantibody transgenes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

V(D)J recombinase induction in splenic B lymphocytes is inhibited by antigen-receptor signalling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Receptor editing: an approach by autoreactive B cells to escape tolerance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

B lymphocytes may escape tolerance by revising their antigen receptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Receptor editing in self-reactive bone marrow B cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Genetic and structural evidence for antigen selection of anti-DNA antibodies.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Light chain editing in kappa-deficient animals: a potential mechanism of B cell tolerance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Light chain replacement: a new model for antibody gene rearrangement

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Breakdown of B cell tolerance in a mouse model of systemic lupus erythematosus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Immunoglobulin chain loss in hybridoma lines

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Clonal deletion of autoreactive B lymphocytes in bone marrow chimeras

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Antinuclear antibodies: diagnostic markers and clues to the basis of systemic autoimmunity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Both IgM and IgG anti-DNA antibodies are the products of clonally selective B cell stimulation in (NZB x NZW)F1 mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

The lupus autoantigens and the pathogenesis of systemic lupus erythematosus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Residues that mediate DNA binding of autoimmune antibodies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

V region gene analysis of anti-Sm hybridomas from MRL/Mp-lpr/lpr mice

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Light chain contribution to specificity in anti-DNA antibodies

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Protection against Fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Linked sets of antinuclear antibodies: what do they mean?

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Variable region genes of anti-histone autoantibodies from a MRL/Mp-lpr/lpr mouse

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Ig H and L chain contributions to autoimmune specificities

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+T cells

28 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.190.5.691

A new role for B cells in systemic autoimmunity: B cells promote spontaneous T cell activation in MRL-lpr/lpr mice.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

DNA-binding antibodies from viable motheaten mutant mice: implications for B cell tolerance

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

B cell selection and allelic exclusion of an anti-DNA Ig transgene in MRL-lpr/lpr mice.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

The mechanism of autoantibody production in an autoimmune MRL/lpr mouse.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195620

The role of clonal selection and somatic mutation in autoimmunity

21 September 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.190.5.691

Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.190.5.691

Editing disease-associated autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.190.5.691

Immunoglobulin heavy chain gene replacement: a mechanism of receptor editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.190.5.691

Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.190.5.691

Oligoclonality of rheumatoid factors arising spontaneously in lpr/lpr mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.190.5.691

Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.190.5.691

Reexpression of RAG-1 and RAG-2 genes in activated mature mouse B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.190.5.691

Effects of the lpr mutation on elimination and inactivation of self-reactive B cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10477553

12 December 2020

inferred from PubMed ID database lookup

Analysis of central B cell tolerance in autoimmune-prone MRL/lpr mice bearing autoantibody transgenes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10477553

12 December 2020

inferred from PubMed ID database lookup

Characterization of B cells expressing recombination activating genes in germinal centers of immunized mouse lymph nodes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10477553

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1084/JEM.190.5.691

1 reference

release_nse5e5ipgfahfanuiwabaqhv3m

13 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/nse5e5ipgfahfanuiwabaqhv3m

24 November 2022

mapped directly with Wikidata item

1 reference

13 August 2017

PubMed publication ID

10477553

1 reference