(Q36375728)

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Neonatal tumor necrosis factor alpha promotes diabetes in nonobese diabetic mice by CD154-independent antigen presentation to CD8(+) T cells.

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Europe PubMed Central

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3 November 2019

Neonatal tumor necrosis factor alpha promotes diabetes in nonobese diabetic mice by CD154-independent antigen presentation to CD8(+) T cells (English)

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3 November 2019

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3 November 2019

Richard Flavell

5

object named as

R A Flavell

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3 November 2019

author name string

E A Green

1

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3 November 2019

K Eshima

3

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3 November 2019

C Mora

4

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3 November 2019

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1 January 2000

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3 November 2019

Journal of Experimental Medicine

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3 November 2019

191

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3 November 2019

225-238

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3 November 2019

2

1 reference

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3 November 2019

Signalling through CD30 protects against autoimmune diabetes mediated by CD8 T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

TRANCE, a tumor necrosis factor family member critical for CD40 ligand-independent T helper cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

CD40 ligand-mediated interactions are involved in the generation of memory CD8(+) cytotoxic T lymphocytes (CTL) but are not required for the maintenance of CTL memory following virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

Reduction of atherosclerosis in mice by inhibition of CD40 signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

Major histocompatibility complex class I-restricted cross-presentation is biased towards high dose antigens and those released during cellular destruction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

CD40 AND CD154 IN CELL-MEDIATED IMMUNITY

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

Dendritic cells and the control of immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

Viral and bacterial infections interfere with peripheral tolerance induction and activate CD8+ T cells to cause immunopathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

Induction of MHC class I expression by the MHC class II transactivator CIITA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

Chronic tumor necrosis factor alters T cell responses by attenuating T cell receptor signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

Constitutive class I-restricted exogenous presentation of self antigens in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

CD40 ligand-deficient mice generate a normal primary cytotoxic T-lymphocyte response but a defective humoral response to a viral infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

Local expression of transgene encoded TNF alpha in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

Functional diversity of helper T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

Regulation of MHC class II genes: lessons from a disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

CD40-CD40 ligand interactions are critical in T-B cooperation but not for other anti-viral CD4+ T cell functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

CD28-B7 interactions allow the induction of CD8+ cytotoxic T lymphocytes in the absence of exogenous help.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

CIITA activates the expression of MHC class II genes in mouse T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

Genes encoding tumor necrosis factor alpha and granzyme A are expressed during development of autoimmune diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

Mice lacking MHC class II molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

Activation of human dendritic cells through CD40 cross-linking.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

30 September 2017

CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CD8+ CTL response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

28 June 2018

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

28 June 2018

Class II transactivator regulates the expression of multiple genes involved in antigen presentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

28 June 2018

Immunotherapy of the nonobese diabetic mouse: treatment with an antibody to T-helper lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

28 June 2018

Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

28 June 2018

B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

21 September 2018

T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

21 September 2018

Help for cytotoxic-T-cell responses is mediated by CD40 signalling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

21 September 2018

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

21 September 2018

Requirement for CD40 ligand in costimulation induction, T cell activation, and experimental allergic encephalomyelitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

21 September 2018

Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

21 September 2018

Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195753

21 September 2018

The role of the T cell costimulator B7-1 in autoimmunity and the induction and maintenance of tolerance to peripheral antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/10637268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of bcl-x by CD40 engagement rescues sIg-induced apoptosis in murine B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10637268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice lacking the MHC class II transactivator (CIITA) show tissue-specific impairment of MHC class II expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/10637268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of CD8+ T cells in the initiation of insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10637268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RIP-beta 2-microglobulin transgene expression restores insulitis, but not diabetes, in beta 2-microglobulin null nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10637268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Major histocompatibility complex class I molecules are required for the development of insulitis in non-obese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10637268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10637268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant

1 reference

https://pubmed.ncbi.nlm.nih.gov/10637268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis is the mode of beta-cell death responsible for the development of IDDM in the nonobese diabetic (NOD) mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/10637268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Site alpha is crucial for two routes of IFN gamma-induced MHC class I transactivation: the ISRE-mediated route and a novel pathway involving CIITA

1 reference

https://pubmed.ncbi.nlm.nih.gov/10637268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 ligand-CD40 interactions are necessary for the initiation of insulitis and diabetes in nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10637268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the MHC class II transactivator CIITA by interferon-gamma requires cooperative interaction between Stat1 and USF-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/10637268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic cells and macrophages are the first and major producers of TNF-alpha in pancreatic islets in the nonobese diabetic mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/10637268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local expression of TNFalpha in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens

1 reference

https://pubmed.ncbi.nlm.nih.gov/10637268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice lacking the transcription factor CIITA--a second look

1 reference

https://pubmed.ncbi.nlm.nih.gov/10637268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pancreatic infiltration but not diabetes occurs in the relative absence of MHC class II-restricted CD4 T cells: studies using NOD/CIITA-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10637268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both the Lyt-2+ and L3T4+ T cell subsets are required for the transfer of diabetes in nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10637268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Following a diabetogenic T cell from genesis through pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10637268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice deficient for the CD40 ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/10637268

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.191.2.225

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10637268%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10637268%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10637268%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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