(Q36382005)

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Commensal Bacteria-induced Interleukin 1β (IL-1β) Secreted by Macrophages Up-regulates Hepcidin Expression in Hepatocytes by Activating the Bone Morphogenetic Protein Signaling Pathway

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Europe PubMed Central

PMC publication ID

13 August 2017

Commensal Bacteria-induced Interleukin 1β (IL-1β) Secreted by Macrophages Up-regulates Hepcidin Expression in Hepatocytes by Activating the Bone Morphogenetic Protein Signaling Pathway (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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1 reference

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author name string

Nanda Kumar N Shanmugam

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Kejie Chen

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Bobby J Cherayil

3

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Europe PubMed Central

PMC publication ID

13 August 2017

language of work or name

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publication date

29 October 2015

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Europe PubMed Central

PMC publication ID

13 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

13 August 2017

290

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Europe PubMed Central

PMC publication ID

13 August 2017

51

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

30637-30647

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Distinct Commensals Induce Interleukin-1β via NLRP3 Inflammasome in Inflammatory Monocytes to Promote Intestinal Inflammation in Response to Injury

1 reference

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Mechanisms of inflammasome activation: recent advances and novel insights

1 reference

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Anemia of inflammation

1 reference

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30 September 2017

Bone morphogenetic proteins as regulators of iron metabolism

1 reference

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30 September 2017

Intestinal inflammation modulates expression of the iron-regulating hormone hepcidin depending on erythropoietic activity and the commensal microbiota

1 reference

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30 September 2017

Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis

1 reference

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The TLR and IL-1 signalling network at a glance

1 reference

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30 September 2017

The role of hepatic transferrin receptor 2 in the regulation of iron homeostasis in the body

1 reference

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30 September 2017

IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans

1 reference

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30 September 2017

Serum-induced up-regulation of hepcidin expression involves the bone morphogenetic protein signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

Systemic iron homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

Hepcidin and the iron-infection axis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

Diversity, stability and resilience of the human gut microbiota

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

Tumor necrosis factor α inhibits expression of the iron regulating hormone hepcidin in murine models of innate colitis

1 reference

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30 September 2017

Ferroportin-mediated iron transport: expression and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

Targeting the hepcidin-ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

Hepatic acute phase proteins--regulation by IL-6- and IL-1-type cytokines involving STAT3 and its crosstalk with NF-κB-dependent signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

The bone morphogenetic protein-hepcidin axis as a therapeutic target in inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

Suppression of hepatic hepcidin expression in response to acute iron deprivation is associated with an increase of matriptase-2 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

Depletion of luminal iron alters the gut microbiota and prevents Crohn's disease-like ileitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

Hepcidin is elevated in mice injected with Mycoplasma arthritidis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

Selective modulation of TLR4-activated inflammatory responses by altered iron homeostasis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

Activated macrophages induce hepcidin expression in HuH7 hepatoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

Two BMP responsive elements, STAT, and bZIP/HNF4/COUP motifs of the hepcidin promoter are critical for BMP, SMAD1, and HJV responsiveness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

Structure-activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

Interleukin-1beta stimulates acute phase response and C-reactive protein synthesis by inducing an NFkappaB- and C/EBPbeta-dependent autocrine interleukin-6 loop

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance

1 reference

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30 September 2017

Systematic review: managing anaemia in Crohn's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

Interleukin-6 induces hepcidin expression through STAT3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

Regulation of hepcidin transcription by interleukin-1 and interleukin-6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

30 September 2017

IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

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Enhanced production of interleukin 1-beta by mononuclear cells isolated from mucosa with active ulcerative colitis of Crohn's disease

1 reference

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Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

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The effects of iron fortification on the gut microbiota in African children: a randomized controlled trial in Cote d'Ivoire

1 reference

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21 September 2018

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

21 September 2018

STAT3 is required for IL-6-gp130-dependent activation of hepcidin in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

21 September 2018

Oral ferrous fumarate or intravenous iron sucrose for patients with inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683283

21 September 2018

Long-term in vitro function of adult hepatocytes in a collagen sandwich configuration

1 reference

https://pubmed.ncbi.nlm.nih.gov/26515063

12 December 2020

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Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2

1 reference

https://pubmed.ncbi.nlm.nih.gov/26515063

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization and cellular sources of activins in normal and fibrotic rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/26515063

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M115.689190

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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