(Q36384719)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17901249%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

title

Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17901249%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

7

1 reference

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8 January 2020

6

Michelle M Le Beau

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17901249%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

author name string

Gina Kirsammer

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17901249%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Sarah Jilani

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17901249%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Hui Liu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17901249%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Elizabeth Davis

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17901249%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Sandeep Gurbuxani

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17901249%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

language of work or name

English

0 references

publication date

27 September 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17901249%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

number of pages

9

1 reference

inferred from page(s)

published in

Blood

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17901249%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

volume

111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17901249%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17901249%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

page(s)

767-775

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17901249%20AND%20SRC:MED&resulttype=core&format=json

The myeloproliferative disorders

8 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

A mutation in the translation initiation codon of Gata-1 disrupts megakaryocyte maturation and causes thrombocytopenia

30 September 2017

1 reference

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Activating alleles of JAK3 in acute megakaryoblastic leukemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

Identification of an acquired JAK2 mutation in polycythemia vera

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

A gain-of-function mutation of JAK2 in myeloproliferative disorders

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

A chromosome 21 critical region does not cause specific Down syndrome phenotypes.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

Recent insights into the mechanisms of myeloid leukemogenesis in Down syndrome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

The management of neoplastic disorders of haematopoiesis in children with Down's syndrome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

The AML1-ETO chimaeric transcription factor in acute myeloid leukaemia: biology and clinical significance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

Alternative translation initiation site usage results in two functionally distinct forms of the GATA-1 transcription factor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

Segmental trisomy as a mouse model for Down syndrome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

AML1 and the 8;21 and 3;21 translocations in acute and chronic myeloid leukemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

The Philadelphia chromosome translocation. A paradigm for understanding leukemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

A mouse model for Down syndrome exhibits learning and behaviour deficits.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

Postnatal lethality and cardiac anomalies in the Ts65Dn Down syndrome mouse model

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

The growth capacity of bone marrow CD34 positive cells in culture is drastically reduced in a murine model of Down syndrome.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

An inherited mutation leading to production of only the short isoform of GATA-1 is associated with impaired erythropoiesis

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

The proto-oncogene ERG in megakaryoblastic leukemias

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

Frequent mutations in the GATA-1 gene in the transient myeloproliferative disorder of Down syndrome

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

Craniofacial phenotypes in segmentally trisomic mouse models for Down syndrome.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

Parallels of craniofacial maldevelopment in Down syndrome and Ts65Dn mice.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2200841

Peripheral blood cell counts in infants with Down's syndrome

21 September 2018

1 reference

12 December 2020

1 reference

12 December 2020

Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1

1 reference

12 December 2020

Intrinsic abnormalities of lymphocyte counts in children with down syndrome

1 reference

12 December 2020

Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice

1 reference

12 December 2020

Mutagenesis of GATA1 is an initiating event in Down syndrome leukemogenesis

1 reference

12 December 2020

Prenatal origin of GATA1 mutations may be an initiating step in the development of megakaryocytic leukemia in Down syndrome

1 reference

12 December 2020

Hematologic abnormalities in children with Down syndrome

1 reference

12 December 2020

10.1182/BLOOD-2007-04-085670

Identifiers

DOI

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ee2qalkg55ezpo7jyzrotmbbp4

30 July 2022

release_ee2qalkg55ezpo7jyzrotmbbp4

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ee2qalkg55ezpo7jyzrotmbbp4

30 July 2022

https://api.fatcat.wiki/v0/release/ee2qalkg55ezpo7jyzrotmbbp4

1 reference

30 July 2022

https://api.fatcat.wiki/v0/release/ee2qalkg55ezpo7jyzrotmbbp4

PubMed publication ID

1 reference

30 July 2022