(Q36386421)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23150798%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

title

Membrane immersion allows rhomboid proteases to achieve specificity by reading transmembrane segment dynamics (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23150798%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

main subject

transmembrane protein

0 references

author

Syed Mohammad Moin

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23150798%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

author name string

Sinisa Urban

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23150798%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

language of work or name

English

0 references

publication date

13 November 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23150798%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23150798%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

volume

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23150798%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

page(s)

e00173

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23150798%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

17 February 2020

copyright license

start time

2 September 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Architectural and thermodynamic principles underlying intramembrane protease function

1 reference

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An internal water-retention site in the rhomboid intramembrane protease GlpG ensures catalytic efficiency

30 September 2017

1 reference

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Mammalian EGF receptor activation by the rhomboid protease RHBDL2

30 September 2017

1 reference

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The structural basis for catalysis and substrate specificity of a rhomboid protease

30 September 2017

1 reference

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The cutting edge: membrane-anchored serine protease activities in the pericellular microenvironment

30 September 2017

1 reference

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Taking the plunge: integrating structural, enzymatic and computational insights into a unified model for membrane-immersed rhomboid proteolysis

30 September 2017

1 reference

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Sequence-specific intramembrane proteolysis: identification of a recognition motif in rhomboid substrates

30 September 2017

1 reference

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How intramembrane proteases bury hydrolytic reactions in the membrane.

30 September 2017

1 reference

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Making the cut: central roles of intramembrane proteolysis in pathogenic microorganisms

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Subsite cooperativity in protease specificity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Rhomboid protease dynamics and lipid interactions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Structure and mechanism of intramembrane protease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

The role of protease activity in ErbB biology

30 September 2017

1 reference

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In vivo analysis reveals substrate-gating mutants of a rhomboid intramembrane protease display increased activity in living cells

30 September 2017

1 reference

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Proteases: multifunctional enzymes in life and disease

30 September 2017

1 reference

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Functional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteases

30 September 2017

1 reference

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The Fas ligand intracellular domain is released by ADAM10 and SPPL2a cleavage in T-cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Enzymatic analysis of a rhomboid intramembrane protease implicates transmembrane helix 5 as the lateral substrate gate

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Rhomboid protease AarA mediates quorum-sensing in Providencia stuartii by activating TatA of the twin-arginine translocase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Two Plasmodium rhomboid proteases preferentially cleave different adhesins implicated in all invasive stages of malaria

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Signal peptide peptidase: biochemical properties and modulation by nonsteroidal antiinflammatory drugs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

SPPL2a and SPPL2b promote intramembrane proteolysis of TNFalpha in activated dendritic cells to trigger IL-12 production

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

A gamma-secretase-like intramembrane cleavage of TNFalpha by the GxGD aspartyl protease SPPL2b

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Mapping of the active site of proteases in the 1960s and rational design of inhibitors/drugs in the 1990s

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Regulation of Mycobacterium tuberculosis cell envelope composition and virulence by intramembrane proteolysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Reconstitution of intramembrane proteolysis in vitro reveals that pure rhomboid is sufficient for catalysis and specificity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Mechanism of intramembrane proteolysis investigated with purified rhomboid proteases.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Purification and characterization of the human gamma-secretase complex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

A family of Rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Alpha-helical, but not beta-sheet, propensity of proline is determined by peptide environment

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Knowledge-based potential for positioning membrane-associated structures and assessing residue-specific energetic contributions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

A comparative study of the phospholipids and fatty acids of some insects.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Site-2 protease regulated intramembrane proteolysis: sequence homologs suggest an ancient signaling cascade

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

The role of context on alpha-helix stabilization: host-guest analysis in a mixed background peptide model

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Sequence features of substrates required for cleavage by GlpG, an Escherichia coli rhomboid protease.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494066

Turns in transmembrane helices: determination of the minimal length of a “helical hairpin” and derivation of a fine-grained turn propensity scale 1 1Edited by F. E. Cohen

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.7554%2FELIFE.00173

An essential role for ectodomain shedding in mammalian development

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23150798

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A turn propensity scale for transmembrane helices

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23150798

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.7554/ELIFE.00173

1 reference

13 August 2017

10.7554/ELIFE.00173.017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23150798%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23150798%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

PubMed publication ID

23150798

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23150798%20AND%20SRC:MED&resulttype=core&format=json