(Q34207965)

31 July 2017

title

Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain (English)

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31 July 2017

main subject

transmembrane protein

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Matthew Freeman

2

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ORCID Public Data File 2021

author name string

Sinisa Urban

series ordinal

1

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31 July 2017

publication date

1 June 2003

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31 July 2017

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31 July 2017

volume

11

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31 July 2017

issue

6

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31 July 2017

page(s)

1425-1434

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Role of the Juxtamembrane Domains of the Transforming Growth Factor-α Precursor and the β-Amyloid Precursor Protein in Regulated Ectodomain Shedding

31 July 2017

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7 January 2021

rhomboid, a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster

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7 January 2021

Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

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The roles of side chain and backbone in protein structure probed with glycine- and sarcosine-rich synthetic leucine zipper peptides.

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7 January 2021

The Toxoplasma adhesive protein MIC2 is proteolytically processed at multiple sites by two parasite-derived proteases

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7 January 2021

Empirical Predictions of Protein Conformation

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A conserved mechanism for extracellular signaling in eukaryotes and prokaryotes.

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brother of rhomboid, a rhomboid-related gene expressed during early Drosophila oogenesis, promotes EGF-R/MAPK signaling

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7 January 2021

The (beta)gamma subunits of G proteins gate a K(+) channel by pivoted bending of a transmembrane segment

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7 January 2021

Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila

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Requirements for signal peptide peptidase-catalyzed intramembrane proteolysis

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Mechanism of the cleavage specificity of Alzheimer's disease gamma-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein

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7 January 2021

Guidelines for membrane protein engineering derived from de novo designed model peptides

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Identification, sequencing and expression of an integral membrane protein of the trans-Golgi network (TGN38)

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Intramembrane cleavage of microneme proteins at the surface of the apicomplexan parasite Toxoplasma gondii

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7 January 2021

Characterization of a mammalian cDNA encoding a protein with high sequence similarity to the Drosophila regulatory protein Rhomboid

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Evolutionary divergence of substrate specificity within the chymotrypsin-like serine protease fold

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Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs

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Microneme proteins: structural and functional requirements to promote adhesion and invasion by the apicomplexan parasite Toxoplasma gondii.

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Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins.

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7 January 2021

Intracellular trafficking by Star regulates cleavage of the Drosophila EGF receptor ligand Spitz

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7 January 2021

Helical membrane proteins: diversity of functions in the context of simple architecture

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7 January 2021

Intramembrane proteolysis controls diverse signalling pathways throughout evolution

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7 January 2021

Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases

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A family of Rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands

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Conservation of intramembrane proteolytic activity and substrate specificity in prokaryotic and eukaryotic rhomboids

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7 January 2021

Control of EGF receptor activation in Drosophila

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7 January 2021

Identification of signal peptide peptidase, a presenilin-type aspartic protease

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7 January 2021

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

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7 January 2021

Asparagine-proline sequence within membrane-spanning segment of SREBP triggers intramembrane cleavage by site-2 protease

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7 January 2021

10.1016/S1097-2765(03)00181-3

Identifiers

DOI

1 reference

31 July 2017

1 reference