(Q36386895)

English

Quantitative proteomics reveals regulation of karyopherin subunit alpha-2 (KPNA2) and its potential novel cargo proteins in nonsmall cell lung cancer

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Quantitative proteomics reveals regulation of karyopherin subunit alpha-2 (KPNA2) and its potential novel cargo proteins in nonsmall cell lung cancer (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1 reference

based on heuristic

inferred from title

7

object named as

Jau-Song Yu

0 references

8

0 references

1

object named as

Chun-I Wang

0 references

2

0 references

Chia-chen Chang

5

0 references

6

0 references

4

0 references

author name string

Chih-Liang Wang

3

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

publication date

25 July 2012

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Molecular & Cellular Proteomics

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

11

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

11

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1105-1122

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Nuclear transport receptor karyopherin-α2 promotes malignant breast cancer phenotypes in vitro

1 reference

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Distinct roles for classical nuclear import receptors in the growth of multinucleated muscle cells

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30 September 2017

High expression of karyopherin-α2 defines poor prognosis in non-muscle-invasive bladder cancer and in patients with invasive bladder cancer undergoing radical cystectomy

1 reference

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30 September 2017

Regulation of nuclear localization signal-importin α interaction by Ca2+/S100A6

1 reference

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30 September 2017

Importin subunit alpha-2 is identified as a potential biomarker for non-small cell lung cancer by integration of the cancer cell secretome and tissue transcriptome

1 reference

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30 September 2017

Functional characterization of ATAD2 as a new cancer/testis factor and a predictor of poor prognosis in breast and lung cancers

1 reference

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30 September 2017

UHRF1 is a novel diagnostic marker of lung cancer.

1 reference

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30 September 2017

The nuclear import of the small GTPase Rac1 is mediated by the direct interaction with karyopherin alpha2.

1 reference

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E2F1 expression is deregulated and plays an oncogenic role in sporadic Burkitt's lymphoma

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30 September 2017

Comparative proteome analysis of human adenocarcinoma

1 reference

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30 September 2017

A practical guide to the MaxQuant computational platform for SILAC-based quantitative proteomics

1 reference

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30 September 2017

Identificating 14-3-3 sigma as a lymph node metastasis-related protein in human lung squamous carcinoma

1 reference

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30 September 2017

Enhancing identifications of lipid-embedded proteins by mass spectrometry for improved mapping of endothelial plasma membranes in vivo

1 reference

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30 September 2017

Identification of karyopherin-alpha 2 as an Oct4 associated protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Cdc7-Dbf4 kinase overexpression in multiple cancers and tumor cell lines is correlated with p53 inactivation

1 reference

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30 September 2017

Gene expression profiling in patients with chronic obstructive pulmonary disease and lung cancer

1 reference

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30 September 2017

FRA-1 proto-oncogene induces lung epithelial cell invasion and anchorage-independent growth in vitro, but is insufficient to promote tumor growth in vivo

1 reference

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30 September 2017

Identification and validation of S100A7 associated with lung squamous cell carcinoma metastasis to brain

1 reference

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30 September 2017

Differential regulation of karyopherin alpha 2 expression by TGF-beta1 and IFN-gamma in normal human epidermal keratinocytes: evident contribution of KPNA2 for nuclear translocation of IRF-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Classical nuclear localization signals: definition, function, and interaction with importin alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Evaluation of claspin as a proliferation marker in human cancer and normal tissues

1 reference

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30 September 2017

Distinct and Overlapping Roles for E2F Family Members in Transcription, Proliferation and Apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Molecular profiling of laser-microdissected matched tumor and normal breast tissue identifies karyopherin alpha2 as a potential novel prognostic marker in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Importin KPNA2, NBS1, DNA repair and tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Importin KPNA2 is required for proper nuclear localization and multiple functions of NBS1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Plakophilin 3 oncogene as prognostic marker and therapeutic target for lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Overexpression of NBS1 contributes to transformation through the activation of phosphatidylinositol 3-kinase/Akt

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Multimodality expression profiling shows SEPT9 to be overexpressed in a wide range of human tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

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Importin alpha transports CaMKIV to the nucleus without utilizing importin beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Importin α: a multipurpose nuclear-transport receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

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A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

1 reference

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A proteomic approach for quantitation of phosphorylation using stable isotope labeling in cell culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Karyopherin-alpha2 protein interacts with Chk2 and contributes to its nuclear import.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Emerging roles for E2F: Beyond the G1/S transition and DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

A revised picture of the E2F transcriptional network and RB function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Amino acid residue specific stable isotope labeling for quantitative proteomics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Sibling rivalry in the E2F family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Karyopherins and nuclear import

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Transport into and out of the nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Multiple pathways contribute to nuclear import of core histones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Nuclear import of histone H2A and H2B is mediated by a network of karyopherins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

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Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis

1 reference

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1 reference

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30 September 2017

Truncated form of importin alpha identified in breast cancer cell inhibits nuclear import of p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

E2F-1: a proliferative marker of breast neoplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Nuclear exclusion of p53 in a subset of tumors requires MDM2 function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Activation of cyclin D1-related kinase in human lung adenocarcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Determination of the functional domain organization of the importin alpha nuclear import factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

1 reference

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30 September 2017

Identification of a novel cytoplasmic protein that specifically binds to nuclear localization signal motifs

1 reference

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30 September 2017

Differential modes of nuclear localization signal (NLS) recognition by three distinct classes of NLS receptors.

1 reference

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Selection of invasive and metastatic subpopulations from a human lung adenocarcinoma cell line

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30 September 2017

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1 reference

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30 September 2017

Differential expression and sequence-specific interaction of karyopherin alpha with nuclear localization sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Subcellular localization of accumulated p53 in ovarian cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Rch1, a protein that specifically interacts with the RAG-1 recombination-activating protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

30 September 2017

Regulation of vascular endothelial growth factor receptors by Rb and E2F1: role of acetylation

1 reference

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Retinoblastoma family proteins have distinct functions in pulmonary epithelial cells in vivo critical for suppressing cell growth and tumorigenesis

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28 June 2018

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28 June 2018

Overexpression of karyopherin-2 in epithelial ovarian cancer and correlation with poor prognosis.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M111.016592

21 January 2018

A novel tumor-associated antigen, cell division cycle 45-like can induce cytotoxic T-lymphocytes reactive to tumor cells.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M111.016592

21 January 2018

Eg5 expression is closely correlated with the response of advanced non-small cell lung cancer to antimitotic agents combined with platinum chemotherapy.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M111.016592

21 January 2018

Selective expression of S100A7 in lung squamous cell carcinomas and large cell carcinomas but not in adenocarcinomas and small cell carcinomas.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M111.016592

21 January 2018

UHRF1-mediated tumor suppressor gene inactivation in nonsmall cell lung cancer.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M111.016592

21 January 2018

Distinct pattern of E2F1 expression in human lung tumours: E2F1 is upregulated in small cell lung carcinoma.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M111.016592

21 January 2018

CUX1 and E2F1 regulate coordinated expression of the mitotic complex genes Ect2, MgcRacGAP, and MKLP1 in S phase.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M111.016592

21 January 2018

Immunohistochemical detection of WT1 protein in a variety of cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494185

21 September 2018

Genetic variation in the DNA repair genes is predictive of outcome in lung cancer

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M111.016592

21 January 2018

Prognostic significance of cytoplasmic p53 overexpression in colorectal cancer. An immunohistochemical analysis

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M111.016592

21 January 2018

Significance of karyopherin-{alpha} 2 (KPNA2) expression in esophageal squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22843992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of A549 lung cancer cell migration by precursor let-7g microRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/22843992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

E2F1 overexpression correlates with thymidylate synthase and survivin gene expressions and tumor proliferation in non small-cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22843992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

E2F-1, Skp2 and cyclin E oncoproteins are upregulated and directly correlated in high-grade neuroendocrine lung tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22843992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of cysteine protease inhibitors stefin A, stefin B, and cystatin C in human lung tumor tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/22843992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KPNA2 expression is an independent adverse predictor of biochemical recurrence after radical prostatectomy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22843992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of p38- and CRM1-dependent nuclear export promotes E2F1 degradation during keratinocyte differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22843992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An intracellular targeted NLS peptide inhibitor of karyopherin alpha:NF-kappa B interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/22843992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between lymphangiogenesis-/micrometastasis- and adhesion-related molecules in resected stage I NSCLC

1 reference

https://pubmed.ncbi.nlm.nih.gov/22843992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cysteine proteases and cysteine protease inhibitors in non-small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22843992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical expression of cyclin D1, E2F-1, and Ki-67 in benign and malignant thyroid lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/22843992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription factor E2F-1 acts as a growth-promoting factor and is associated with adverse prognosis in non-small cell lung carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22843992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three-gene expression signature predicts survival in early-stage squamous cell carcinoma of the lung

1 reference

https://pubmed.ncbi.nlm.nih.gov/22843992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

E2F1 stability is regulated by a novel-PKC/p38β MAP kinase signaling pathway during keratinocyte differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22843992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/MCP.M111.016592

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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