(Q36392829)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16470223%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

Dissection of the NF-kappaB signalling cascade in transgenic and knockout mice (English)

1 reference

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16 January 2020

0 references

1 reference

1

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16 January 2020

author name string

Luedde T

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16470223%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Schmidt-Supprian M

series ordinal

3

1 reference

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16 January 2020

publication date

1 May 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16470223%20AND%20SRC:MED&resulttype=core&format=json

Cell Death & Differentiation

16 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16470223%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16470223%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16470223%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

page(s)

861-872

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16470223%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401870

16 January 2020

exact match

0 references

cites work

NF-kappaB regulation in the immune system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

NEMO/IKK gamma-deficient mice model incontinentia pigmenti.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Limb and skin abnormalities in mice lacking IKKalpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

IKK1-deficient mice exhibit abnormal development of skin and skeleton

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

IKKalpha controls formation of the epidermis independently of NF-kappaB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

IkappaB kinase-alpha acts in the epidermis to control skeletal and craniofacial morphogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Control of lymphocyte development by nuclear factor-kappaB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Conditional gene targeting

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

IKKβ Is Required for Peripheral B Cell Survival and Proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion injury

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

IKK-beta links inflammation to obesity-induced insulin resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

I kappa B kinase 2 deficiency in T cells leads to defects in priming, B cell help, germinal center reactions, and homeostatic expansion.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Mature T cells depend on signaling through the IKK complex.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

IKKβ Is Required for Prevention of Apoptosis Mediated by Cell-Bound but Not by Circulating TNFα

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

The two faces of IKK and NF-κB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

IkappaB kinase signaling is essential for maintenance of mature B cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

IKK mediates ischemia-induced neuronal death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Conditional gene targeting in macrophages and granulocytes using LysMcre mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Hematopoietic stem cells expressing the myeloid lysozyme gene retain long-term, multilineage repopulation potential.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Signaling pathways and genes that inhibit pathogen-induced macrophage apoptosis--CREB and NF-kappaB as key regulators

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-kappaB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Expression of constitutively active IkappaB beta in T cells of transgenic mice: persistent NF-kappaB activity is required for T-cell immune responses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

NF-kappa B is required for the positive selection of CD8+ thymocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

High susceptibility to bacterial infection, but no liver dysfunction, in mice compromised for hepatocyte NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Hepatocyte-specific inhibition of NF-kappaB leads to apoptosis after TNF treatment, but not after partial hepatectomy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Nuclear factor-{kappa}B activity in {beta}-cells is required for glucose-stimulated insulin secretion.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Forebrain-specific neuronal inhibition of nuclear factor-kappaB activity leads to loss of neuroprotection.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Inhibition of astroglial nuclear factor kappaB reduces inflammation and improves functional recovery after spinal cord injury

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Cardiac-specific abrogation of NF- kappa B activation in mice by transdominant expression of a mutant I kappa B alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

IKKbeta/NF-kappaB activation causes severe muscle wasting in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

A prominent role for airway epithelial NF-kappa B activation in lipopolysaccharide-induced airway inflammation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

I-kappa B kinase beta is critical for B cell proliferation and antibody response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

I-kappa B kinases alpha and beta have distinct roles in regulating murine T cell function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Functional redundancy of the nuclear factor kappa B inhibitors I kappa B alpha and I kappa B beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Distinct NF-kappa B/Rel transcription factors are responsible for tissue-specific and inducible gene activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Constitutive nuclear factor-kappa B activity is required for central neuron survival.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

In vivo pattern of lipopolysaccharide and anti-CD3-induced NF-kappa B activation using a novel gene-targeted enhanced GFP reporter gene mouse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Inhibition of NF-kappaB activity and enhancement of apoptosis by the neuropeptide calcitonin gene-related peptide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

In vivo imaging of NF-kappa B activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Multiorgan nuclear factor kappa B activation in a transgenic mouse model of systemic inflammation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Real-time imaging of ligand-induced IKK activation in intact cells and in living mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

The role of Rel/NF-kappaB transcription factors in B lymphocyte survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

The role of nuclear factor-kappaB essential modulator (NEMO) in B cell development and survival.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Activation of NF-kappaB promotes the transition of large, CD43+ pre-B cells to small, CD43- pre-B cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

An intact NF-kappa B signaling pathway is required for maintenance of mature B cell subsets

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Lymphocytes lacking I kappa B-alpha develop normally, but have selective defects in proliferation and function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

IkappaBalpha/IkappaBepsilon deficiency reveals that a critical NF-kappaB dosage is required for lymphocyte survival.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Chronic inflammation and susceptibility to bacterial infections in mice lacking the polypeptide (p)105 precursor (NF-kappaB1) but expressing p50.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

NF-kappaB in cancer: from innocent bystander to major culprit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Abnormal immune function of hemopoietic cells from alymphoplasia (aly) mice, a natural strain with mutant NF-kappa B-inducing kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

IkappaB kinase alpha is essential for mature B cell development and function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Gastric hyperplasia and increased proliferative responses of lymphocytes in mice lacking the COOH-terminal ankyrin domain of NF-kappaB2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

TRAF2 differentially regulates the canonical and noncanonical pathways of NF-kappaB activation in mature B cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Inducible gene targeting in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Oncogenes, tumor suppressors and p52 NF-κB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Inhibition of NF-kappaB in T cells blocks lymphoproliferation and partially rescues autoimmune disease in gld/gld mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

An essential role for nuclear factor kappaB in promoting double positive thymocyte apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Inhibition of NF-kappa B activity in T and NK cells results in defective effector cell expansion and production of IFN-gamma required for resistance to Toxoplasma gondii.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Survival-independent function of NF-κB⧹Rel during late stages of thymocyte differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

IKKbeta is essential for protecting T cells from TNFalpha-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Differential dependence of CD4+CD25+ regulatory and natural killer-like T cells on signals leading to NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Differential requirement for Rel/nuclear factor kappa B family members in natural killer T cell development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Lethal effect of the anti-Fas antibody in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

LPS-induced liver injury in D-galactosamine-sensitized mice requires secreted TNF-alpha and the TNF-p55 receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosamine-treated mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

NFkappaB prevents apoptosis and liver dysfunction during liver regeneration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

1 reference

7 January 2021

NF-kappaB functions as a tumour promoter in inflammation-associated cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021

Stroma-mediated dysregulation of myelopoiesis in mice lacking I kappa B alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401870

7 January 2021