(Q36401362)

English

Engineered zinc-finger proteins can compensate genetic haploinsufficiency by transcriptional activation of the wild-type allele: application to Willams-Beuren syndrome and supravalvular aortic stenosis

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Engineered zinc-finger proteins can compensate genetic haploinsufficiency by transcriptional activation of the wild-type allele: application to Willams-Beuren syndrome and supravalvular aortic stenosis (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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haploinsufficiency

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supravalvular aortic stenosis

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William C. Sessa

6

object named as

William C Sessa

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Europe PubMed Central

PMC publication ID

14 August 2017

author name string

Pei Zhang

1

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Europe PubMed Central

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14 August 2017

Angela Huang

2

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Europe PubMed Central

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14 August 2017

Manuel Morales-Ruiz

3

1 reference

Europe PubMed Central

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14 August 2017

Barry C Starcher

4

1 reference

Europe PubMed Central

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14 August 2017

Yan Huang

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Laura E Niklason

7

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Europe PubMed Central

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14 August 2017

Frank J Giordano

8

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Europe PubMed Central

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14 August 2017

publication date

1 November 2012

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14 August 2017

Human Gene Therapy

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14 August 2017

23

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Europe PubMed Central

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14 August 2017

11

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Europe PubMed Central

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14 August 2017

1186-1199

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Europe PubMed Central

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14 August 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3498887/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

1 reference

Europe PubMed Central

22 June 2022

https://europepmc.org/article/PMC/3498887

based on heuristic

inferred from PubMed Central ID database lookup

Inhibition of microRNA-29 enhances elastin levels in cells haploinsufficient for elastin and in bioengineered vessels--brief report

1 reference

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Genetic modifiers of cardiovascular phenotype caused by elastin haploinsufficiency act by extrinsic noncomplementation

1 reference

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1 reference

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1 reference

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1 reference

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Genome editing with engineered zinc finger nucleases

1 reference

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1 reference

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Human vascular smooth muscle cells lack essential costimulatory molecules to activate allogeneic memory T cells

1 reference

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The discovery of zinc fingers and their development for practical applications in gene regulation and genome manipulation

1 reference

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Homology models for domains 21-23 of human tropoelastin shed light on lysine crosslinking.

1 reference

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30 September 2017

Modular system for the construction of zinc-finger libraries and proteins

1 reference

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30 September 2017

The discovery of zinc fingers and their applications in gene regulation and genome manipulation.

1 reference

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30 September 2017

Williams-Beuren syndrome.

1 reference

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Identification and characterization of seven novel mutations of elastin gene in a cohort of patients affected by supravalvular aortic stenosis

1 reference

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Effects of mechanical stretch on collagen and cross-linking in engineered blood vessels

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Mechanisms and treatment of cardiovascular disease in Williams-Beuren syndrome.

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New insights into elastic fiber assembly

1 reference

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An improved zinc-finger nuclease architecture for highly specific genome editing

1 reference

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Applying elastic fibre biology in vascular tissue engineering.

1 reference

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Standardized reagents and protocols for engineering zinc finger nucleases by modular assembly.

1 reference

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Regulation of elastin promoter by lysyl oxidase and growth factors: cross control of lysyl oxidase on TGF-beta1 effects

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Elastic fibres in health and disease

1 reference

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Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases

1 reference

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An engineered VEGF-activating zinc finger protein transcription factor improves blood flow and limb salvage in advanced-age mice.

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Elastic fiber macro-assembly is a hierarchical, cell motion-mediated process

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Regulation of elastin gene transcription by interleukin-1 beta-induced C/EBP beta isoforms

1 reference

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1 reference

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Connection between elastin haploinsufficiency and increased cell proliferation in patients with supravalvular aortic stenosis and Williams-Beuren syndrome

1 reference

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Isolated supravalvular aortic stenosis: functional haploinsufficiency of the elastin gene as a result of nonsense-mediated decay

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1 reference

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Phorbol ester-mediated downregulation of tropoelastin expression is controlled by a posttranscriptional mechanism.

1 reference

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1 reference

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Regulation of elastin gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/22891920

12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22891920

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based on heuristic

inferred from PubMed ID database lookup

Functional rescue of elastin insufficiency in mice by the human elastin gene: implications for mouse models of human disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22891920

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Pathophysiology of pelvic organ prolapse

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MicroRNA-29 in Aortic Dilation: Implications for Aneurysm Formation

1 reference

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inferred from PubMed ID database lookup

Identifiers

10.1089/HUM.2011.201

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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