(Q36401915)

English

Development of musculoskeletal toxicity without clear benefit after administration of PG-116800, a matrix metalloproteinase inhibitor, to patients with knee osteoarthritis: a randomized, 12-month, double-blind, placebo-controlled study

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Development of musculoskeletal toxicity without clear benefit after administration of PG-116800, a matrix metalloproteinase inhibitor, to patients with knee osteoarthritis: a randomized, 12-month, double-blind, placebo-controlled study (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

0 references

0 references

knee osteoarthritis

1 reference

based on heuristic

inferred from title

9

object named as

Tim D Spector

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

author name string

Piotr Krzeski

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Chris Buckland-Wright

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Géza Bálint

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Gary A Cline

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Karen Stoner

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Robert Lyon

6

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

John Beary

7

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

William S Aronstein

8

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

publication date

1 January 2007

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Arthritis Research and Therapy

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

9

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

R109

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

https://scigraph.springernature.com/pub.10.1186/ar2315

0 references

Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

30 September 2017

A phase III randomized trial of BAY 12-9566 (tanomastat) as maintenance therapy in patients with advanced ovarian cancer responsive to primary surgery and paclitaxel/platinum containing chemotherapy: a National Cancer Institute of Canada [...]

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

30 September 2017

Efficacy and tolerability of lumiracoxib 100 mg once daily in knee osteoarthritis: a 13-week, randomized, double-blind study vs. placebo and celecoxib

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

30 September 2017

Phase III study of matrix metalloproteinase inhibitor prinomastat in non-small-cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

30 September 2017

Matrix metalloproteinase inhibitors--an emphasis on gastrointestinal malignancies

1 reference

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30 September 2017

Marimastat as maintenance therapy for patients with advanced gastric cancer: a randomised trial

1 reference

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30 September 2017

Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

1 reference

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30 September 2017

Matrix metalloproteinase inhibitors in rheumatic diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

30 September 2017

The inhibition of metalloproteinases as a therapeutic target in rheumatoid arthritis and osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

30 September 2017

Ongoing trials with matrix metalloproteinase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

30 September 2017

Metalloproteinase inhibitors: new opportunities for the treatment of rheumatoid arthritis and osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

30 September 2017

Clinical potential of matrix metalloprotease inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

30 September 2017

Intraarticular sodium hyaluronate (Hyalgan) in the treatment of patients with osteoarthritis of the knee: a randomized clinical trial. Hyalgan Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

30 September 2017

Ro 32-3555, an orally active collagenase inhibitor, prevents cartilage breakdown in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

30 September 2017

Metalloproteinase inhibitors and the prevention of connective tissue breakdown

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

30 September 2017

Quantitative microfocal radiography detects changes in OA knee joint space width in patients in placebo controlled trial of NSAID therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

30 September 2017

Abnormal findings on magnetic resonance images of asymptomatic shoulders.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

30 September 2017

Accuracy and precision of joint space width measurements in standard and macroradiographs of osteoarthritic knees

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

30 September 2017

Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

30 September 2017

Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

30 September 2017

Sequential Treatment Assignment with Balancing for Prognostic Factors in the Controlled Clinical Trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

30 September 2017

Phase I trial of Marimastat, a novel matrix metalloproteinase inhibitor, administered orally to patients with advanced lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

28 June 2018

Matrix metalloproteinase inhibition as a novel anticancer strategy: a review with special focus on batimastat and marimastat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

28 June 2018

Highly water-soluble matrix metalloproteinases inhibitors and their effects in a rat adjuvant-induced arthritis model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

21 September 2018

Phase II trial of temozolomide plus the matrix metalloproteinase inhibitor, marimastat, in recurrent and progressive glioblastoma multiforme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

21 September 2018

Moderation of iodoacetate-induced experimental osteoarthritis in rats by matrix metalloproteinase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

21 September 2018

Dupuytren's disease and frozen shoulder induced by treatment with a matrix metalloproteinase inhibitor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

21 September 2018

Combined analysis of studies of the effects of the matrix metalloproteinase inhibitor marimastat on serum tumor markers in advanced cancer: selection of a biologically active and tolerable dose for longer-term studies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

21 September 2018

Mono-iodoacetate-induced experimental osteoarthritis: a dose-response study of loss of mobility, morphology, and biochemistry.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

21 September 2018

Glucosamine and Chondroitin Sulfate for Knee Osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212568

5 December 2018

Ro 32-3555, an orally active collagenase selective inhibitor, prevents structural damage in the STR/ORT mouse model of osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17958901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Marimastat in patients with advanced pancreatic cancer: a dose-finding study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17958901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pilot study of the safety and effects of the matrix metalloproteinase inhibitor marimastat in gastric cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17958901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover

1 reference

https://pubmed.ncbi.nlm.nih.gov/17958901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metalloproteinases, tissue inhibitor, and proteoglycan fragments in knee synovial fluid in human osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17958901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incidence of symptomatic hand, hip, and knee osteoarthritis among patients in a health maintenance organization

1 reference

https://pubmed.ncbi.nlm.nih.gov/17958901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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Europe PubMed Central

PMC publication ID

14 August 2017

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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