(Q36407793)

English

Prolyl hydroxylase 3 (PHD3) modulates catabolic effects of tumor necrosis factor-α (TNF-α) on cells of the nucleus pulposus through co-activation of nuclear factor κB (NF-κB)/p65 signaling

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Prolyl hydroxylase 3 (PHD3) modulates catabolic effects of tumor necrosis factor-α (TNF-α) on cells of the nucleus pulposus through co-activation of nuclear factor κB (NF-κB)/p65 signaling (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

0 references

0 references

author name string

Nobuyuki Fujita

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Shilpa S Gogate

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Kazuhiro Chiba

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Yoshiaki Toyama

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Irving M Shapiro

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Makarand V Risbud

6

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

language of work or name

0 references

publication date

4 September 2012

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

287

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

47

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

39942-39953

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Expression of prolyl hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc: distinct roles of PHD2 and PHD3 proteins in controlling HIF-1α activity in hypoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501017

30 September 2017

HIF-1α and HIF-2α degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501017

30 September 2017

TNF-α and IL-1β promote a disintegrin-like and metalloprotease with thrombospondin type I motif-5-mediated aggrecan degradation through syndecan-4 in intervertebral disc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501017

30 September 2017

Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501017

30 September 2017

Nuclear factor-κB2/p100 promotes endometrial carcinoma cell survival under hypoxia in a HIF-1α independent manner.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501017

30 September 2017

A hypoxia-dependent upregulation of hypoxia-inducible factor-1 by nuclear factor-κB promotes gastric tumour growth and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501017

30 September 2017

HIF prolyl hydroxylase inhibition increases cell viability and potentiates dopamine release in dopaminergic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501017

30 September 2017

Proinflammatory cytokine expression profile in degenerated and herniated human intervertebral disc tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501017

30 September 2017

Prolyl hydroxylase EGLN3 regulates skeletal myoblast differentiation through an NF-kappaB-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501017

30 September 2017

Prolyl hydroxylase-3 is down-regulated in colorectal cancer cells and inhibits IKKbeta independent of hydroxylase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501017

30 September 2017

Regulation of hypoxia-inducible factor-1alpha by NF-kappaB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501017

30 September 2017

Tumor necrosis factor-alpha modulates matrix production and catabolism in nucleus pulposus tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501017

30 September 2017

The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501017

30 September 2017

Regulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501017

30 September 2017

Applied bioinformatics for the identification of regulatory elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501017

30 September 2017

Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501017

30 September 2017

IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501017

30 September 2017

Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501017

30 September 2017

Oxygen and lactate concentrations measured in vivo in the intervertebral discs of patients with scoliosis and back pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501017

30 September 2017

Identification of a functional hypoxia-responsive element that regulates the expression of the egl nine homologue 3 (egln3/phd3) gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501017

28 June 2018

Vertebral endplate architecture and vascularization: application of micro-computerized tomography, a vascular tracer, and immunocytochemistry in analyses of disc degeneration in the aging sand rat.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375964

21 January 2018

Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375964

21 January 2018

Surgical treatment for the painful motion segment: matching technology with the indications: posterior lumbar fusion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375964

21 January 2018

Interleukin‐1β induces angiogenesis and innervation in human intervertebral disc degeneration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375964

21 January 2018

Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375964

21 January 2018

Magnetic resonance classification of lumbar intervertebral disc degeneration.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375964

21 January 2018

The Human Intervertebral Disc: A Micro-Angiographical Study on Its Vascular Supply at Various Ages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375964

21 January 2018

Differential regulation of matrix degrading enzymes in a TNFalpha-induced model of nucleus pulposus tissue degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/22948157

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22948157

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymph and blood supply of the human intervertebral disc. Cadaver study of correlations to discitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22948157

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and Distribution of Tumor Necrosis Factor Alpha in Human Lumbar Intervertebral Discs: A Study in Surgical Specimen and Autopsy Controls

1 reference

https://pubmed.ncbi.nlm.nih.gov/22948157

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.375964

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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