(Q36409051)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109710%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109710%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

0 references

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109710%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

author name string

Tom M McCaughtry

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109710%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Ruth Etzensperger

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109710%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Amala Alag

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109710%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Xuguang Tai

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109710%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Sema Kurtulus

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109710%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Alex Grinberg

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109710%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Paul Love

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109710%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Lionel Feigenbaum

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109710%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Batu Erman

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109710%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Alfred Singer

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109710%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

language of work or name

English

0 references

publication date

29 October 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109710%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

16 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109710%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

volume

209

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109710%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109710%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

page(s)

2263-2276

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109710%20AND%20SRC:MED&resulttype=core&format=json

IL-15 regulates homeostasis and terminal maturation of NKT cells

16 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

Coreceptor gene imprinting governs thymocyte lineage fate.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

Gamma(c) deficiency precludes CD8+ T cell memory despite formation of potent T cell effectors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

Thymic emigration revisited

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

ITK and IL-15 support two distinct subsets of CD8+ T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

Cytokine signal transduction is suppressed in preselection double-positive thymocytes and restored by positive selection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

Regulation of mature T cell homeostasis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

Dual functions of Runx proteins for reactivating CD8 and silencing CD4 at the commitment process into CD8 thymocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

A role for thymic stromal lymphopoietin in CD4(+) T cell development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

Control of Effector CD8 + T Cell Function by the Transcription Factor Eomesodermin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

Morpholino antisense oligonucleotide-mediated gene knockdown during thymocyte development reveals role for Runx3 transcription factor in CD4 silencing during development of CD4-/CD8+ thymocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

Unraveling a revealing paradox: Why major histocompatibility complex I-signaled thymocytes "paradoxically" appear as CD4+8lo transitional cells during positive selection of CD8+ T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

In vitro evidence that cytokine receptor signals are required for differentiation of double positive thymocytes into functionally mature CD8+ T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

Positive and negative selection of T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

IL-7 is critical for homeostatic proliferation and survival of naive T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of a functional heteromeric complex requires interleukin 7 receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

CD8 coreceptor extinction in signaled CD4(+)CD8(+) thymocytes: coordinate roles for both transcriptional and posttranscriptional regulatory mechanisms in developing thymocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

The common cytokine receptor gamma chain and the pre-T cell receptor provide independent but critically overlapping signals in early alpha/beta T cell development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

A family of cytokine-inducible inhibitors of signalling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

The V-J recombination of T cell receptor-gamma genes is blocked in interleukin-7 receptor-deficient mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

IL-7 receptor and VDJ recombination: trophic versus mechanistic actions

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501363

IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells.

28 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20121505

Suppressor of cytokine signaling-1 is a critical regulator of interleukin-7-dependent CD8+ T cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20121505

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20121505

Control of the development of CD8αα+ intestinal intraepithelial lymphocytes by TGF-β.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20121505

A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20121505

Asymmetric signaling requirements for thymocyte commitment to the CD4+ versus CD8+ T cell lineages: a new perspective on thymic commitment and selection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20121505

Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20121505

IL-2, -7, and -15, but not thymic stromal lymphopoeitin, redundantly govern CD4+Foxp3+ regulatory T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20121505

Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20121505

IL-7 is a growth and maintenance factor for mature and immature thymocyte subsets

21 January 2018

1 reference

PubMed

12 December 2020

The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection

1 reference

PubMed

12 December 2020

Coreceptor reversal in the thymus: signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells

1 reference

PubMed

12 December 2020

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20121505

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109710%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109710%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

PubMed publication ID

23109710

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109710%20AND%20SRC:MED&resulttype=core&format=json