(Q36412541)

14 August 2017

Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease (English)

1 reference

14 August 2017

Brynn N Akerberg

1

1 reference

14 August 2017

Maithri L Sarangam

series ordinal

2

1 reference

14 August 2017

Kryn Stankunas

series ordinal

3

1 reference

14 August 2017

language of work or name

English

0 references

publication date

19 June 2015

1 reference

14 August 2017

15

1 reference

inferred from page(s)

published in

Developmental Biology

1 reference

14 August 2017

407

1 reference

14 August 2017

1

1 reference

14 August 2017

158-172

1 reference

describes a project that uses

14 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4694578/fullTextXML

inferred from PubMed Central ID database lookup

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Normal and abnormal development of the aortic wall and valve: correlation with clinical entities

30 September 2017

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Sequential and opposing activities of Wnt and BMP coordinate zebrafish bone regeneration

30 September 2017

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SWI/SNF chromatin-remodeling factor Smarcd3/Baf60c controls epithelial-mesenchymal transition by inducing Wnt5a signaling

30 September 2017

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30 September 2017

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30 September 2017

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Endocardial to myocardial notch-wnt-bmp axis regulates early heart valve development

30 September 2017

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Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma

30 September 2017

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Insufficient versican cleavage and Smad2 phosphorylation results in bicuspid aortic and pulmonary valves

30 September 2017

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Brg1 governs distinct pathways to direct multiple aspects of mammalian neural crest cell development

30 September 2017

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30 September 2017

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Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome

30 September 2017

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30 September 2017

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Deficient signaling via Alk2 (Acvr1) leads to bicuspid aortic valve development

30 September 2017

1 reference

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Islet1 derivatives in the heart are of both neural crest and second heart field origin

30 September 2017

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Maladaptive matrix remodeling and regional biomechanical dysfunction in a mouse model of aortic valve disease.

30 September 2017

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Altered versican cleavage in ADAMTS5 deficient mice; a novel etiology of myxomatous valve disease

30 September 2017

1 reference

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Loss of Gata5 in mice leads to bicuspid aortic valve

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Nfatc1 coordinates valve endocardial cell lineage development required for heart valve formation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development. [corrected]

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Chromatin remodelling complex dosage modulates transcription factor function in heart development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Cardiac neural crest orchestrates remodeling and functional maturation of mouse semilunar valves

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

VEGF signaling has distinct spatiotemporal roles during heart valve development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Chromatin regulation by Brg1 underlies heart muscle development and disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Bicuspid aortic valve disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Reduced versican cleavage due to Adamts9 haploinsufficiency is associated with cardiac and aortic anomalies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Topographic Anatomy and Histology of the Valves in the Human Heart.

30 September 2017

1 reference

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Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

BMP4 is required in the anterior heart field and its derivatives for endocardial cushion remodeling, outflow tract septation, and semilunar valve development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Cardiovascular and hematopoietic defects associated with Notch1 activation in embryonic Tie2-expressing populations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Periostin regulates atrioventricular valve maturation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

The chromatin-remodeling enzyme BRG1 plays an essential role in primitive erythropoiesis and vascular development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Genome-wide impact of the BRG1 SWI/SNF chromatin remodeler on the transforming growth factor beta transcriptional program

30 September 2017

1 reference

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A global double-fluorescent Cre reporter mouse

30 September 2017

1 reference

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Combined loss of Hey1 and HeyL causes congenital heart defects because of impaired epithelial to mesenchymal transition

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Mutations in NOTCH1 cause aortic valve disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Collagen triple helix repeat containing 1, a novel secreted protein in injured and diseased arteries, inhibits collagen expression and promotes cell migration

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Baf60c is essential for function of BAF chromatin remodelling complexes in heart development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Morphology of bicuspid aortic valve in children and adolescents.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Defective valvulogenesis in HB-EGF and TACE-null mice is associated with aberrant BMP signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

The incidence of congenital heart disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Fate of the mammalian cardiac neural crest

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

A prospective study to assess the frequency of familial clustering of congenital bicuspid aortic valve

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Mouse and human neuronal pentraxin 1 (NPTX1): conservation, genomic structure, and chromosomal localization

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Neural crest cells contribute to normal aorticopulmonary septation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

The observation of collagen and elastin structures in wet whole mounts of pulmonary and aortic leaflets

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Association between bicuspid aortic valve phenotype and patterns of valvular dysfunction and bicuspid aortopathy: comprehensive evaluation using MDCT and echocardiography

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Endocardial cells form the coronary arteries by angiogenesis through myocardial-endocardial VEGF signaling

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Differential activation of valvulogenic, chondrogenic, and osteogenic pathways in mouse models of myxomatous and calcific aortic valve disease

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

The chemokine receptor CXCR7 functions to regulate cardiac valve remodeling

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Periostin is required for maturation and extracellular matrix stabilization of noncardiomyocyte lineages of the heart

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Temporal and distinct TGFbeta ligand requirements during mouse and avian endocardial cushion morphogenesis.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Cardiac neural crest cells provide new insight into septation of the cardiac outflow tract: aortic sac to ventricular septal closure.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Induction of endocardial cushion tissue in the avian heart is regulated, in part, by TGFbeta-3-mediated autocrine signaling.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

The extracellular matrix glycoproteins BM-90 and tenascin are expressed in the mesenchyme at sites of endothelial-mesenchymal conversion in the embryonic mouse heart.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

NPTX1 regulates neural lineage specification from human pluripotent stem cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Neural crest cells are required for correct positioning of the developing outflow cushions and pattern the arterial valve leaflets

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Brg1 governs a positive feedback circuit in the hair follicle for tissue regeneration and repair.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Three-dimensional and molecular analysis of the arterial pole of the developing human heart

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Analysis of the endocardial-to-mesenchymal transformation of heart valve development by collagen gel culture assay.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Notch initiates the endothelial-to-mesenchymal transition in the atrioventricular canal through autocrine activation of soluble guanylyl cyclase.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

The inter-relationship of periostin, TGF beta, and BMP in heart valve development and valvular heart diseases.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Bicuspid aortic valves with different spatial orientations of the leaflets are distinct etiological entities.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Reassessment of Isl1 and Nkx2-5 cardiac fate maps using a Gata4-based reporter of Cre activity.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Neural crest cells retain multipotential characteristics in the developing valves and label the cardiac conduction system.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Lineage and morphogenetic analysis of the cardiac valves.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Development of heart valve leaflets and supporting apparatus in chicken and mouse embryos

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694578

Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis

21 September 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2015.06.015

Familial congenital bicuspid aortic valve: a disorder of uncertain inheritance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2015.06.015

Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2015.06.015

Extracellular Matrix Remodeling and Organization in Developing and Diseased Aortic Valves

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2015.06.015

Periostin (an osteoblast-specific factor) is expressed within the embryonic mouse heart during valve formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2015.06.015

Frequency by decades of unicuspid, bicuspid, and tricuspid aortic valves in adults having isolated aortic valve replacement for aortic stenosis, with or without associated aortic regurgitation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2015.06.015

Invasion of mesenchyme into three-dimensional collagen gels: a regional and temporal analysis of interaction in embryonic heart tissue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2015.06.015

Progression of human aortic valve stenosis is associated with tenascin-C expression

7 January 2021

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26100917

12 December 2020

inferred from PubMed ID database lookup

The morphology of the normal aortic valve as compared with the aortic valve having two leaflets

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26100917

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.YDBIO.2015.06.015

1 reference

14 August 2017

1 reference

14 August 2017

PubMed publication ID

26100917

1 reference