(Q36413157)

English

Mer or Axl receptor tyrosine kinase inhibition promotes apoptosis, blocks growth and enhances chemosensitivity of human non-small cell lung cancer

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Mer or Axl receptor tyrosine kinase inhibition promotes apoptosis, blocks growth and enhances chemosensitivity of human non-small cell lung cancer (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

apoptotic process

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1 reference

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author name string

R M A Linger

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

R A Cohen

2

1 reference

Europe PubMed Central

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14 August 2017

C T Cummings

3

1 reference

Europe PubMed Central

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14 August 2017

S Sather

4

1 reference

Europe PubMed Central

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14 August 2017

J Migdall-Wilson

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

D H G Middleton

6

1 reference

Europe PubMed Central

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14 August 2017

X Lu

7

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

A E Barón

8

1 reference

Europe PubMed Central

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14 August 2017

W A Franklin

9

1 reference

Europe PubMed Central

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14 August 2017

D T Merrick

10

1 reference

Europe PubMed Central

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14 August 2017

P Jedlicka

11

1 reference

Europe PubMed Central

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14 August 2017

D DeRyckere

12

1 reference

Europe PubMed Central

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14 August 2017

L E Heasley

13

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Europe PubMed Central

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14 August 2017

D K Graham

14

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14 August 2017

language of work or name

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publication date

13 August 2012

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Europe PubMed Central

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14 August 2017

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Europe PubMed Central

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14 August 2017

32

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Europe PubMed Central

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14 August 2017

29

1 reference

Europe PubMed Central

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14 August 2017

3420-3431

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Prognostic value of survivin in patients with non-small cell lung carcinoma: a systematic review with meta-analysis

1 reference

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Mer receptor tyrosine kinase inhibition impedes glioblastoma multiforme migration and alters cellular morphology

1 reference

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1 reference

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Profiling of antibody production against xenograft-released proteins by protein microarrays discovers prostate cancer markers

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GDC-0980 is a novel class I PI3K/mTOR kinase inhibitor with robust activity in cancer models driven by the PI3K pathway

1 reference

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Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis

1 reference

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Novel therapeutic targets in non-small cell lung cancer

1 reference

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Distinct roles of Bcl-2 and Bcl-Xl in the apoptosis of human bone marrow mesenchymal stem cells during differentiation

1 reference

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Increased plasma levels of the soluble Mer tyrosine kinase receptor in systemic lupus erythematosus relate to disease activity and nephritis

1 reference

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Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations

1 reference

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Knockdown of oncogenic KRAS in non-small cell lung cancers suppresses tumor growth and sensitizes tumor cells to targeted therapy

1 reference

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30 September 2017

Plasma concentrations of Gas6 and sAxl correlate with disease activity in systemic lupus erythematosus

1 reference

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30 September 2017

PMA up-regulates the transcription of Axl by AP-1 transcription factor binding to TRE sequences via the MAPK cascade in leukaemia cells

1 reference

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30 September 2017

Taking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic targets in solid tumors

1 reference

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An anti-Axl monoclonal antibody attenuates xenograft tumor growth and enhances the effect of multiple anticancer therapies

1 reference

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30 September 2017

Inhibition of Mer and Axl receptor tyrosine kinases in astrocytoma cells leads to increased apoptosis and improved chemosensitivity

1 reference

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TNF-alpha, IL-6, and IL-1 expression is inhibited by GAS6 in monocytes/macrophages

1 reference

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30 September 2017

Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival

1 reference

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1 reference

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30 September 2017

Novel mechanism of lapatinib resistance in HER2-positive breast tumor cells: activation of AXL.

1 reference

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30 September 2017

Axl as a potential therapeutic target in cancer: role of Axl in tumor growth, metastasis and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3502700

30 September 2017

Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers

1 reference

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30 September 2017

Genetic predictors of MEK dependence in non-small cell lung cancer

1 reference

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30 September 2017

Intraclass correlations: uses in assessing rater reliability

1 reference

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30 September 2017

PIK3CA mutations and copy number gains in human lung cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3502700

30 September 2017

TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3502700

30 September 2017

Axl promotes cell invasion by inducing MMP-9 activity through activation of NF-kappaB and Brg-1.

1 reference

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AXL is a potential target for therapeutic intervention in breast cancer progression.

1 reference

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Growth suppression of lung cancer cells by targeting cyclic AMP response element-binding protein

1 reference

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PF00299804, an irreversible pan-ERBB inhibitor, is effective in lung cancer models with EGFR and ERBB2 mutations that are resistant to gefitinib

1 reference

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Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer

1 reference

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Clonogenic assay of cells in vitro.

1 reference

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Adhesion-related kinase induction of migration requires phosphatidylinositol-3-kinase and ras stimulation of rac activity in immortalized gonadotropin-releasing hormone neuronal cells

1 reference

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A novel tyrosine kinase switch is a mechanism of imatinib resistance in gastrointestinal stromal tumors

1 reference

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Gas6/Axl signaling activates the phosphatidylinositol 3-kinase/Akt1 survival pathway to protect oligodendrocytes from tumor necrosis factor alpha-induced apoptosis

1 reference

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Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival

1 reference

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Expression of axl in lung adenocarcinoma and correlation with tumor progression

1 reference

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Altered ErbB receptor signaling and gene expression in cisplatin-resistant ovarian cancer

1 reference

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Somatic mutations of the HER2 kinase domain in lung adenocarcinomas.

1 reference

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30 September 2017

A role for Mer tyrosine kinase in alphavbeta5 integrin-mediated phagocytosis of apoptotic cells.

1 reference

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ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions

1 reference

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Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3

1 reference

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Adhesion-related kinase repression of gonadotropin-releasing hormone gene expression requires Rac activation of the extracellular signal-regulated kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3502700

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Mer receptor tyrosine kinase signaling: prevention of apoptosis and alteration of cytoskeletal architecture without stimulation or proliferation

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Gas6 anti-apoptotic signaling requires NF-kappa B activation.

1 reference

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30 September 2017

Phagocytosis and clearance of apoptotic cells is mediated by MER.

1 reference

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Bcl-2 overexpression results in reciprocal downregulation of Bcl-X(L) and sensitizes human testicular germ cell tumours to chemotherapy-induced apoptosis

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1 reference

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Axl receptor tyrosine kinase expression in human lung cancer cell lines correlates with cellular adhesion

1 reference

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1 reference

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BRAF and RAS mutations in human lung cancer and melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22890323

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of an apoptosis-resistant variant of human leukemia HL-60 cells that has switched expression from Bcl-2 to Bcl-xL

1 reference

https://pubmed.ncbi.nlm.nih.gov/22890323

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/ONC.2012.355

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

ResearchGate publication ID

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