(Q36415115)

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DNA replication stress response involving PLK1, CDC6, POLQ, RAD51 and CLASPIN upregulation prognoses the outcome of early/mid-stage non-small cell lung cancer patients.

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27 February 2020

DNA replication stress response involving PLK1, CDC6, POLQ, RAD51 and CLASPIN upregulation prognoses the outcome of early/mid-stage non-small cell lung cancer patients (English)

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27 February 2020

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27 February 2020

Marie Walschaerts

5

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27 February 2020

Julien Mazieres

11

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27 February 2020

Philippe Pasero

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27 February 2020

author name string

C Allera-Moreau

1

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27 February 2020

I Rouquette

2

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27 February 2020

N Oumouhou

4

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27 February 2020

E Leconte

6

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27 February 2020

V Schilling

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27 February 2020

K Gordien

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27 February 2020

L Brouchet

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27 February 2020

M B Delisle

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27 February 2020

J S Hoffmann

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27 February 2020

C Cazaux

14

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27 February 2020

publication date

22 October 2012

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27 February 2020

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27 February 2020

1

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27 February 2020

e30

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27 February 2020

https://scigraph.springernature.com/pub.10.1038/oncsis.2012.29

0 references

An extra allele of Chk1 limits oncogene-induced replicative stress and promotes transformation

1 reference

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30 September 2017

Plk1 and CK2 act in concert to regulate Rad51 during DNA double strand break repair

1 reference

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30 September 2017

A practical molecular assay to predict survival in resected non-squamous, non-small-cell lung cancer: development and international validation studies

1 reference

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30 September 2017

Prognostic and predictive value of a malignancy-risk gene signature in early-stage non-small cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503291

30 September 2017

Plk1 phosphorylation of Orc2 promotes DNA replication under conditions of stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503291

30 September 2017

Brca2, Rad51 and Mre11: performing balancing acts on replication forks

1 reference

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30 September 2017

Targeting ATR and Chk1 kinases for cancer treatment: a new model for new (and old) drugs

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30 September 2017

HERC2 Interacts with Claspin and regulates DNA origin firing and replication fork progression

1 reference

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30 September 2017

Prognostic and predictive gene signature for adjuvant chemotherapy in resected non-small-cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503291

30 September 2017

DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503291

30 September 2017

53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503291

30 September 2017

Gene expression-based prognostic signatures in lung cancer: ready for clinical use?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503291

30 September 2017

Increased origin activity in transformed versus normal cells: identification of novel protein players involved in DNA replication and cellular transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503291

30 September 2017

Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study

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30 September 2017

Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication.

1 reference

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30 September 2017

An oncogene-induced DNA damage model for cancer development

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30 September 2017

Interaction between HMGA1a and the origin recognition complex creates site-specific replication origins

1 reference

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30 September 2017

Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503291

30 September 2017

Mutation at the polymerase active site of mouse DNA polymerase delta increases genomic instability and accelerates tumorigenesis

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30 September 2017

Involvement of DNA polymerase mu in the repair of a specific subset of DNA double-strand breaks in mammalian cells.

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30 September 2017

Evaluation of claspin as a proliferation marker in human cancer and normal tissues

1 reference

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30 September 2017

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

1 reference

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30 September 2017

Mechanisms of common fragile site instability.

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30 September 2017

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

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30 September 2017

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

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30 September 2017

High-efficiency bypass of DNA damage by human DNA polymerase Q

1 reference

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30 September 2017

Overexpression of the replication licensing regulators hCdt1 and hCdc6 characterizes a subset of non-small-cell lung carcinomas: synergistic effect with mutant p53 on tumor growth and chromosomal instability--evidence of E2F-1 transcriptional contro

1 reference

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30 September 2017

Polo-like kinases and the orchestration of cell division

1 reference

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30 September 2017

Clinical impact of ATR checkpoint signalling failure in humans

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30 September 2017

Divide and conquer: nucleotide excision repair battles cancer and ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503291

30 September 2017

Considering the cancer consequences of altered DNA polymerase function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503291

30 September 2017

Oncogenic potential of the DNA replication licensing protein CDT1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503291

30 September 2017

Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503291

30 September 2017

https://api.crossref.org/works/10.1038%2FONCSIS.2012.29

21 January 2018

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503291

30 September 2017

Requirement of mammalian DNA polymerase-beta in base-excision repair.

1 reference

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30 September 2017

Mechanisms of DNA excision repair

1 reference

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30 September 2017

Hereditary nonpolyposis colorectal cancer: the syndrome, the genes, and historical perspectives.

1 reference

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30 September 2017

Human DNA polymerase eta is required for common fragile site stability during unperturbed DNA replication

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30 September 2017

Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis

1 reference

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28 June 2018

Functions of the BRCA1 and BRCA2 genes

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28 June 2018

MutS homologue 2 and the long-term benefit of adjuvant chemotherapy in lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503291

21 September 2018

A 'DNA replication' signature of progression and negative outcome in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503291

21 September 2018

DNA polymerase theta (POLQ) can extend from mismatches and from bases opposite a (6-4) photoproduct

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503291

21 September 2018

DNA synthesis and repair genes RRM1 and ERCC1 in lung cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503291

21 September 2018

A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice.

1 reference

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21 September 2018

MCM8 is an MCM2-7-related protein that functions as a DNA helicase during replication elongation and not initiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503291

21 September 2018

Control of DNA replication and its potential clinical exploitation.

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21 September 2018

Prognostic value of p53 in non-small cell lung cancer: Relationship with proliferating cell nuclear antigen and cigarette smoking

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https://api.crossref.org/works/10.1038%2FONCSIS.2012.29

31 March 2020

Tumor progression and loss of heterozygosity at 5q and 18q in non-small cell lung cancer

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12 December 2020

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10.1038/ONCSIS.2012.29

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23552402%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

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27 February 2020

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27 February 2020

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