(Q36417107)

English

Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis

scientific article published on 10 July 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

neurodegeneration

1 reference

based on heuristic

inferred from title

human embryonic stem cell

1 reference

based on heuristic

inferred from title

whole genome sequencing

1 reference

based on heuristic

inferred from title

object named as

Robert Walker

6

0 references

Daniah Trabzuni

object named as

Daniah Trabzuni

3

0 references

Patrick A. Lewis

object named as

Patrick A Lewis

2

0 references

object named as

Rickie Patani

1

0 references

Giles E. Hardingham

object named as

Giles E Hardingham

8

0 references

Michael E. Weale

object named as

Michael Weale

9

0 references

object named as

David J A Wyllie

5

0 references

John Anthony Hardy

10

object named as

John Hardy

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

12

object named as

Mina Ryten

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

author name string

Clare A Puddifoot

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Colin Smith

7

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Siddharthan Chandran

11

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

language of work or name

0 references

publication date

10 July 2012

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Journal of Neurochemistry

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

122

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

738-751

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

Spatio-temporal transcriptome of the human brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

Comprehensive gene expression analysis of human embryonic stem cells during differentiation into neural cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

Modelling schizophrenia using human induced pluripotent stem cells

1 reference

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30 September 2017

Retinoid-independent motor neurogenesis from human embryonic stem cells reveals a medial columnar ground state

1 reference

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30 September 2017

LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress

1 reference

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30 September 2017

Human stem cell-derived neurons: a system to study human tau function and dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

What can pluripotent stem cells teach us about neurodegenerative diseases?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

Dynamic transcriptomes during neural differentiation of human embryonic stem cells revealed by short, long, and paired-end sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

Activin/Nodal inhibition alone accelerates highly efficient neural conversion from human embryonic stem cells and imposes a caudal positional identity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

Functional and evolutionary insights into human brain development through global transcriptome analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

Developmental regulation of neural cell adhesion molecule in human prefrontal cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

Induced pluripotent stem cells from a spinal muscular atrophy patient

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

Directed differentiation of ventral spinal progenitors and motor neurons from human embryonic stem cells by small molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

Alternative splicing events identified in human embryonic stem cells and neural progenitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

A scaleable and defined system for generating neural stem cells from human embryonic stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

Structural basis for the inhibition of activin signalling by follistatin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

Tau gene alternative splicing: expression patterns, regulation and modulation of function in normal brain and neurodegenerative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

Derivation of midbrain dopamine neurons from human embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

Differentiation of embryonic stem cells to a neural fate: a route to re-building the nervous system?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

1 reference

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30 September 2017

Directed differentiation of embryonic stem cells into motor neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

30 September 2017

Specific targeting of pro-death NMDA receptor signals with differing reliance on the NR2B PDZ ligand

1 reference

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21 September 2018

Phosphatidylinositol 3 kinase activation and AMPA receptor subunit trafficking underlie the potentiation of miniature EPSC amplitudes triggered by the activation of L-type calcium channels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

21 September 2018

Embryonic stem cell-derived neural progenitors display temporal restriction to neural patterning.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

21 September 2018

Neural differentiation of mouse embryonic stem cells in chemically defined medium.

1 reference

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21 September 2018

Specification of motoneurons from human embryonic stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

21 September 2018

Differentiation of human embryonic stem cells to dopaminergic neurons in serum-free suspension culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

21 September 2018

Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504076

21 September 2018

Identifiers

10.1111/J.1471-4159.2012.07825.X

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

ResearchGate publication ID

0 references

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