(Q36417840)

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(R)-alpha-lipoic acid reverses the age-related loss in GSH redox status in post-mitotic tissues: evidence for increased cysteine requirement for GSH synthesis

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

(R)-alpha-lipoic acid reverses the age-related loss in GSH redox status in post-mitotic tissues: evidence for increased cysteine requirement for GSH synthesis (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

author name string

Jung H Suh

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Hong Wang

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Rui-Ming Liu

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

JianKang Liu

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Tory M Hagen

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

language of work or name

0 references

publication date

1 March 2004

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Archives of Biochemistry and Biophysics

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

423

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

126-135

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Plasma Kinetics, Metabolism, and Urinary Excretion of Alpha‐Lipoic Acid following Oral Administration in Healthy Volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

Glutathione in defense and signaling: lessons from a small thiol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

Cellular glutathione and thiols metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

Uptake, recycling, and antioxidant actions of alpha-lipoic acid in endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

Polymorphism in the 5'-flanking region of human glutamate-cysteine ligase modifier subunit gene is associated with myocardial infarction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

Mitochondrial decay in the aging rat heart: evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

New metabolic pathways of alpha-lipoic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

Oxidative stress in the aging rat heart is reversed by dietary supplementation with (R)-(alpha)-lipoic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

[5-3H]glucose overestimates glycolytic flux in isolated working rat heart: role of the pentose phosphate pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

Antioxidants, oxidative stress, and degenerative neurological disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

Regulation of gamma-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

Regulation of hepatic glutathione synthesis: current concepts and controversies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

Conjugates of catecholamines with cysteine and GSH in Parkinson's disease: possible mechanisms of formation involving reactive oxygen species.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

Modulation of cellular reducing equivalent homeostasis by alpha-lipoic acid. Mechanisms and implications for diabetes and ischemic injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

Neuroprotection by the metabolic antioxidant alpha-lipoic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

Oxidants, antioxidants, and the degenerative diseases of aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

Cloning and sequencing of the cDNA for the light subunit of human liver gamma-glutamylcysteine synthetase and relative mRNA levels for heavy and light subunits in human normal tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

Transport of cystine and cysteine in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

Glutathione deficiency produced by inhibition of its synthesis, and its reversal; Applications in research and therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

Free radical theory of aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

The systemic availability of oral glutathione

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

30 September 2017

Effect of aging on tryptophan hydroxylase in rat brain: implications on serotonin level.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

28 June 2018

Mitochondrial function, GSH and iron in neurodegeneration and Lewy body diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

28 June 2018

Development of NADPH-producing pathways in rat heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

28 June 2018

Changes in superoxide radical and lipid peroxide formation in the brain, heart and liver during the lifetime of the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

28 June 2018

Functional glutaredoxin (thioltransferase) activity in rat brain and liver mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

21 September 2018

The neuroprotective antioxidant alpha-lipoic acid induces detoxication enzymes in cultured astroglial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

21 September 2018

Oxidative damage increases with age in a canine model of human brain aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

21 September 2018

Down-regulation of gamma-glutamylcysteine synthetase regulatory subunit gene expression in rat brain tissue during aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

21 September 2018

4-Hydroxy-2-nonenal increases gamma-glutamylcysteine synthetase gene expression in alveolar epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

21 September 2018

Age-associated decline in gamma-glutamylcysteine synthetase gene expression in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

21 September 2018

Lipoic acid increases de novo synthesis of cellular glutathione by improving cystine utilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

21 September 2018

Absorption of [7,8-14C]rac-a-lipoic acid from in situ ligated segments of the gastrointestinal tract of the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

21 September 2018

Development of NADPH-consuming pathways in heart, brain and liver of the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696556

21 September 2018

High-performance liquid chromatography of thiols and disulfides: dinitrophenol derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/14871476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Energy-linked cardiac transport system for glutathione disulfide

1 reference

https://pubmed.ncbi.nlm.nih.gov/14871476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delta-6-desaturation of linoleic and alpha-linolenic acids in aged rats: a kinetic analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14871476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of gamma-glutamyl-cysteine synthetase by nonallosteric feedback inhibition by glutathione

1 reference

https://pubmed.ncbi.nlm.nih.gov/14871476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiac transport of glutathione disulfide and S-conjugate. Studies with isolated perfused rat heart during hydroperoxide metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/14871476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related changes in LTP and antioxidant defenses are reversed by an α-lipoic acid-enriched diet

1 reference

https://pubmed.ncbi.nlm.nih.gov/14871476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catalytic and regulatory properties of the heavy subunit of rat kidney gamma-glutamylcysteine synthetase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14871476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione and lipid peroxidation in the aging rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/14871476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uptake and distribution of N-acetylcysteine in mice: tissue-specific effects on glutathione concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/14871476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between aging, drug treatment and the cerebral enzymatic antioxidant system

1 reference

https://pubmed.ncbi.nlm.nih.gov/14871476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipoic acid metabolism in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/14871476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of a microplate reader in an assay of glutathione reductase using 5,5'-dithiobis(2-nitrobenzoic acid)

1 reference

https://pubmed.ncbi.nlm.nih.gov/14871476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(R)-alpha-lipoic acid reverses the age-associated increase in susceptibility of hepatocytes to tert-butylhydroperoxide both in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/14871476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.ABB.2003.12.020

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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