(Q34011426)

English

Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid (English)

1 reference

Europe PubMed Central

30 July 2017

3

object named as

Bruce N Ames

1 reference

Europe PubMed Central

30 July 2017

author name string

Jiankang Liu

1

1 reference

Europe PubMed Central

30 July 2017

David W Killilea

2

1 reference

Europe PubMed Central

30 July 2017

language of work or name

0 references

publication date

1 February 2002

1 reference

Europe PubMed Central

30 July 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

30 July 2017

99

1 reference

Europe PubMed Central

30 July 2017

1876-1881

1 reference

Europe PubMed Central

30 July 2017

4

1 reference

Europe PubMed Central

30 July 2017

Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Proteasomes and proteasome inhibition in the central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Garbage catastrophe theory of aging: imperfect removal of oxidative damage?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Oxidative stress in the aging rat heart is reversed by dietary supplementation with (R)-(alpha)-lipoic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Carnitine acyltransferases: functional significance of subcellular distribution and membrane topology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Micronutrients prevent cancer and delay aging

1 reference

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5 July 2018

Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Iron accumulation in aging: modulation by dietary restriction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Carnitine acyltransferases are not changed in Alzheimer disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

The free radical theory of aging matures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Assay of aldehydes from lipid peroxidation: gas chromatography-mass spectrometry compared to thiobarbituric acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Neuroprotection by the metabolic antioxidant alpha-lipoic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Alpha-lipoic acid: a metabolic antioxidant and potential redox modulator of transcription.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Inhibition studies of the carnitine acetyltransferase from skeletal muscle of the camel (Camelus dromedarius) by sulfhydryl reagents and metal ions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Oxidants, antioxidants, and the degenerative diseases of aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Oxidative damage and mitochondrial decay in aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Comparison of the mutagenicities of malondialdehyde and the side products formed during its chemical synthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

The aging process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Inactivation of key metabolic enzymes by mixed-function oxidation reactions: possible implication in protein turnover and ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Some kinetic studies on the mechanism of action of carnitine acetyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Carnitine Acetyltransferase in Nervous Tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

The biologic clock: the mitochondria?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

The natural history of homocystinuria due to cystathionine beta-synthase deficiency.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Levels of carnitines in brain and other tissues of rats of different ages: effect of acetyl-L-carnitine administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Carnitine acetyltransferase activity is not changed with age in rat brain and human platelets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Effect of aging on the activity of the phosphate carrier and on the lipid composition in rat liver mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Carnitine function and requirements during the life cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Cholinergic systems in muscle and brain in vitamin E-deficient rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Lipid oxidation by heart mitochondria from young adult and senescent rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Fatal ataxic encephalopathy and carnitine acetyltransferase deficiency: A functional defect of pyruvate oxidation?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

5 July 2018

Mitochondrial decay in aging. Reversal through supplementation of acetyl-L-carnitine and N-tert-butyl-alpha-phenyl-nitrone

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261709098

21 January 2018

The effects of dietary restriction on mitochondrial dysfunction in aging.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261709098

21 January 2018

Carnitine acetyltransferase activity in the human brain and its microvessels is decreased in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261709098

21 January 2018

Carnitine, carnitine acetyltransferase, and glutathione in Alzheimer brain.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261709098

21 January 2018

Muscle carnitine acetyltransferase and carnitine deficiency in a case of mitochondrial encephalomyopathy.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261709098

21 January 2018

Assay of malondialdehyde and other alkanals in biological fluids by gas chromatography-mass spectrometry.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261709098

21 January 2018

Determination of standard zinc values in the intact tissues of mice by ICP spectrometry.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261709098

21 January 2018

Assay of malondialdehyde in biological fluids by gas chromatography-mass spectrometry.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261709098

21 January 2018

Alpha-lipoic acid and alpha-lipoamide prevent oxidant-induced lysosomal rupture and apoptosis

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.261709098

21 January 2018

(R)-alpha-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

29 October 2018

Age-associated decline in ascorbic acid concentration, recycling, and biosynthesis in rat hepatocytes--reversal with (R)-alpha-lipoic acid supplementation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122287

29 October 2018

Age-linked changes in the activity of enzymes of the tricarboxylate cycle and lipid oxidation, and of carnitine content, in muscles of the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/11854488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related changes in the activity of the pyruvate carrier and in the lipid composition in rat-heart mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/11854488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscle carnitine deficiency in patients with severe peripheral vascular disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11854488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of aging and acetyl-L-carnitine on the activity of the phosphate carrier and on the phospholipid composition in rat heart mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/11854488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased activity of the phosphate carrier and modification of lipids in cardiac mitochondria from senescent rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11854488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

X-linked pyridoxine-responsive sideroblastic anemia due to a Thr388-to-Ser substitution in erythroid 5-aminolevulinate synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11854488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related changes in LTP and antioxidant defenses are reversed by an α-lipoic acid-enriched diet

1 reference

https://pubmed.ncbi.nlm.nih.gov/11854488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(R)-alpha-lipoic acid reverses the age-associated increase in susceptibility of hepatocytes to tert-butylhydroperoxide both in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/11854488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of aging and acetyl-L-carnitine on the function and on the lipid composition of rat heart mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/11854488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of aging and acetyl-L-carnitine on the activity of cytochrome oxidase and adenine nucleotide translocase in rat heart mitochondria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11854488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thioctic (lipoic) acid: a therapeutic metal-chelating antioxidant?

1 reference

https://pubmed.ncbi.nlm.nih.gov/11854488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiolipin-dependent decrease of cytochrome c oxidase activity in heart mitochondria from hypothyroid rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11854488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of NADH-linked mitochondrial respiration by 4-hydroxy-2-nonenal

1 reference

https://pubmed.ncbi.nlm.nih.gov/11854488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective inactivation of alpha-ketoglutarate dehydrogenase and pyruvate dehydrogenase: reaction of lipoic acid with 4-hydroxy-2-nonenal

1 reference

https://pubmed.ncbi.nlm.nih.gov/11854488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of aging and acetyl-L-carnitine on the pyruvate transport and oxidation in rat heart mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/11854488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CARNITINE ACETYLTRANSFERASE. II. INHIBIITON BY CARNITINE ANALOGUES AND BY SULFHYDRYL REAGENTS

1 reference

https://pubmed.ncbi.nlm.nih.gov/11854488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.261709098

1 reference

Europe PubMed Central

30 July 2017

2002PNAS...99.1876L

0 references

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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