(Q36418892)

English

Connective tissue growth factor regulates retinal neovascularization through p53 protein-dependent transactivation of the matrix metalloproteinase (MMP)-2 gene

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scholarly article

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Europe PubMed Central

PMC publication ID

14 August 2017

Connective tissue growth factor regulates retinal neovascularization through p53 protein-dependent transactivation of the matrix metalloproteinase (MMP)-2 gene (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

connective tissue

1 reference

based on heuristic

inferred from title

neovascularization

1 reference

based on heuristic

inferred from title

7

object named as

Maria B Grant

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

author name string

Hembindu Chintala

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Haibo Liu

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Rahul Parmar

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Monika Kamalska

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Yoon Ji Kim

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

David Lovett

6

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Brahim Chaqour

8

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

language of work or name

0 references

publication date

9 October 2012

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

287

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

48

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

40570-40585

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Matrix metalloproteinase-2 or -9 deletions protect against hemorrhagic transformation during early stage of cerebral ischemia and reperfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

p53-Dependent pathways in neurite outgrowth and axonal regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Role of connective tissue growth factor in the retinal vasculature during development and ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

The role of connective tissue growth factor (CTGF/CCN2) in skeletogenesis

1 reference

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30 September 2017

The matricellular protein cysteine-rich protein 61 (CCN1/Cyr61) enhances physiological adaptation of retinal vessels and reduces pathological neovascularization associated with ischemic retinopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Retinopathy of prematurity: an epidemic in the making

1 reference

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30 September 2017

A mouse strain where basal connective tissue growth factor gene expression can be switched from low to high

1 reference

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30 September 2017

Retinopathy of prematurity: understanding ischemic retinal vasculopathies at an extreme of life

1 reference

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30 September 2017

Differential modulation of angiogenesis by erythropoiesis-stimulating agents in a mouse model of ischaemic retinopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Astrocyte-derived vascular endothelial growth factor stabilizes vessels in the developing retinal vasculature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Matrix metalloproteinase-2 in the development of diabetic retinopathy and mitochondrial dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

The opposing effects of CCN2 and CCN5 on the development of cardiac hypertrophy and fibrosis

1 reference

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30 September 2017

Regulation of angiogenesis by macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

EPCs and pathological angiogenesis: when good cells go bad.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

FoxO proteins mediate hypoxic induction of connective tissue growth factor in endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Deadly liaisons: fatal attraction between CCN matricellular proteins and the tumor necrosis factor family of cytokines

1 reference

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30 September 2017

Mechanical regulation of the proangiogenic factor CCN1/CYR61 gene requires the combined activities of MRTF-A and CREB-binding protein histone acetyltransferase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Oxidative stress and the development of diabetic retinopathy: contributory role of matrix metalloproteinase-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Connective tissue growth factor (CTGF, CCN2) gene regulation: a potent clinical bio-marker of fibroproliferative disease?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Role of CCN, a vertebrate specific gene family, in development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Functions and mechanisms of action of CCN matricellular proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

The angio-fibrotic switch of VEGF and CTGF in proliferative diabetic retinopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Connective tissue growth factor is necessary for retinal capillary basal lamina thickening in diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Connective tissue growth factor as a mediator of intraocular fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Pathogenesis of retinopathy of prematurity and possible preventive strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Cyr61/CCN1 and CTGF/CCN2 mediate the proangiogenic activity of VHL-mutant renal carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Identification of candidate angiogenic inhibitors processed by matrix metalloproteinase 2 (MMP-2) in cell-based proteomic screens: disruption of vascular endothelial growth factor (VEGF)/heparin affin regulatory peptide (pleiotrophin) and VEGF/Conne

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Angiogenesis is not impaired in connective tissue growth factor (CTGF) knock-out mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

IGF binding protein-3 regulates hematopoietic stem cell and endothelial precursor cell function during vascular development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

CCN family proteins and angiogenesis: from embryo to adulthood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

TNF-alpha is critical for ischemia-induced leukostasis, but not retinal neovascularization nor VEGF-induced leakage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Mechanical stretch modulates the promoter activity of the profibrotic factor CCN2 through increased actin polymerization and NF-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Intronic regulation of matrix metalloproteinase-2 revealed by in vivo transcriptional analysis in ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Individual domains of connective tissue growth factor regulate fibroblast proliferation and myofibroblast differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Mechanisms of hypoxic gene regulation of angiogenesis factor Cyr61 in melanoma cells.

1 reference

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30 September 2017

Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development

1 reference

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A functional activating protein 1 (AP-1) site regulates matrix metalloproteinase 2 (MMP-2) transcription by cardiac cells through interactions with JunB-Fra1 and JunB-FosB heterodimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Chordin-like CR domains and the regulation of evolutionarily conserved extracellular signaling systems.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Connective tissue growth factor binds vascular endothelial growth factor (VEGF) and inhibits VEGF-induced angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

How matrix metalloproteinases regulate cell behavior

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

The angiogenic factor Cyr61 activates a genetic program for wound healing in human skin fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Regulation of connective tissue growth factor gene expression in retinal vascular endothelial cells by angiogenic growth factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Extrinsic regulators of epithelial tumor progression: metalloproteinases

1 reference

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30 September 2017

Identification and classification of p53-regulated genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

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Fisp12/mouse connective tissue growth factor mediates endothelial cell adhesion and migration through integrin alphavbeta3, promotes endothelial cell survival, and induces angiogenesis in vivo

1 reference

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Transcriptional activation by p53 of the human type IV collagenase (gelatinase A or matrix metalloproteinase 2) promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Cyr61 and Fisp12 are both ECM-associated signaling molecules: activities, metabolism, and localization during development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Astrocyte hypoxic response is essential for pathological but not developmental angiogenesis of the retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

30 September 2017

Dynamics of angiogenesis during murine retinal development: a coupled in vivo and in silico study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

28 June 2018

Pharmacologic and genetic manipulation of MMP-2 and -9 affects retinal neovascularization in rodent models of OIR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

28 June 2018

A role for endothelial cells in promoting the maturation of astrocytes through the apelin/APJ system in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

21 September 2018

Cysteine-rich protein 61 and connective tissue growth factor induce deadhesion and anoikis of retinal pericytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

21 September 2018

Pathological but not physiological retinal neovascularization is altered in TNF-Rp55-receptor-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

21 September 2018

Brain-derived neurotrophic factor gene delivery to muller glia preserves structure and function of light-damaged photoreceptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

21 September 2018

Accumulation of NH2-terminal fragment of connective tissue growth factor in the vitreous of patients with proliferative diabetic retinopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

21 September 2018

Leukocytes mediate retinal vascular remodeling during development and vaso-obliteration in disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

21 September 2018

Lentiviral gene transfer to the nonhuman primate brain

1 reference

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21 September 2018

Tissue-specific enhancer-promoter interactions regulate high level constitutive expression of matrix metalloproteinase 2 by glomerular mesangial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504771

21 September 2018

Role of Matrix Metalloproteinases in Blood Flow–Induced Arterial Enlargement

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.386565

21 January 2018

[Angiogenesis and vasculogenesis. Therapeutic strategies for stimulation of postnatal neovascularization]

1 reference

https://pubmed.ncbi.nlm.nih.gov/23048035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombospondin-1 induces matrix metalloproteinase-2 activation in vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23048035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxygen-induced retinopathy in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/23048035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Connective tissue growth factor induces the proliferation, migration, and tube formation of vascular endothelial cells in vitro, and angiogenesis in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/23048035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advanced glycosylation end products up-regulate connective tissue growth factor (insulin-like growth factor-binding protein-related protein 2) in human fibroblasts: a potential mechanism for expansion of extracellular matrix in diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/23048035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor induces expression of connective tissue growth factor via KDR, Flt1, and phosphatidylinositol 3-kinase-akt-dependent pathways in retinal vascular cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23048035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Connective tissue growth factor/CCN2 stimulates actin disassembly through Akt/protein kinase B-mediated phosphorylation and cytoplasmic translocation of p27(Kip-1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/23048035

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.386565

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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