(Q36425981)

14 August 2017

1 reference

title

Adrenomedullin: a new and promising target for drug discovery (English)

1 reference

Sonsoles Martín-Santamaría

14 August 2017

1 reference

Sonsoles Martín-Santamaría

Beatriz de Pascual-Teresa

2

0 references

Beatriz de Pascual-Teresa

3

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Ana Ramos

Ana Ramos

4

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Alfredo Martínez

Alfredo Martínez

6

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author name string

Mario A García

1

1 reference

14 August 2017

Miguel Julián

5

1 reference

14 August 2017

language of work or name

English

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publication date

1 April 2006

1 reference

Expert Opinion on Therapeutic Targets

14 August 2017

published in

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14 August 2017

volume

10

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14 August 2017

issue

2

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14 August 2017

page(s)

303-317

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Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma

14 August 2017

cites work

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Adrenomedullin as a pancreatic hormone.

21 January 2018

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Adrenomedullin: a new target for the design of small molecule modulators with promising pharmacological activities

21 January 2018

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Intermedin is a calcitonin/calcitonin gene-related peptide family peptide acting through the calcitonin receptor-like receptor/receptor activity-modifying protein receptor complexes

21 January 2018

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International Union of Pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors

21 January 2018

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Characterization of adrenomedullin in birds.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.10.2.303

The clinical relevance of adrenomedullin: a promising profile?

21 January 2018

1 reference

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Cloning and characterization of cDNA encoding a precursor for human adrenomedullin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Cell and molecular biology of the multifunctional peptide, adrenomedullin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Complement factor H is a serum-binding protein for adrenomedullin, and the resulting complex modulates the bioactivities of both partners

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Adrenomedullin and related peptides: receptors and accessory proteins

21 January 2018

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Adrenomedullin receptors: molecular identity and function.

21 January 2018

1 reference

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The receptor activity modifying protein family of G protein coupled receptor accessory proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

CL/RAMP2 and CL/RAMP3 produce pharmacologically distinct adrenomedullin receptors: a comparison of effects of adrenomedullin22-52, CGRP8-37 and BIBN4096BS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Novel function for receptor activity-modifying proteins (RAMPs) in post-endocytic receptor trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Receptor activity-modifying protein (RAMP) isoform-specific regulation of adrenomedullin receptor trafficking by NHERF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Involvement of G protein-coupled receptor kinase-6 in desensitization of CGRP receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

An investigation into the antimicrobial effects of adrenomedullin on members of the skin, oral, respiratory tract and gut microflora

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Adrenomedullin expression is up-regulated by ischemia-reperfusion in the cerebral cortex of the adult rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Adrenomedullin receptor binding sites in rat brain and peripheral tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Adrenomedullin acts in the rat paraventricular nucleus to decrease blood pressure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Adrenomedullin in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Cardiac adrenomedullin: its role in cardiac hypertrophy and heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Adrenomedullin and its related peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Cardiovascular and sympathetic effects of proadrenomedullin NH2-terminal 20 peptide in conscious rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Plasma levels of adrenomedullin, a newly identified hypotensive peptide, in patients with hypertension and renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Efficacy of the non-peptide CGRP receptor antagonist BIBN4096BS in blocking CGRP-induced dilations in human and bovine cerebral arteries: potential implications in acute migraine treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Adrenomedullin inhibits ovalbumin-induced bronchoconstriction and airway microvascular leakage in guinea-pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Urinary adrenomedullin is related to ET-1 and salt intake in patients with mild essential hypertension. Salt Sensitivity Group of Italian Society of Hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Calcitonin gene-related peptide as a GH secretagogue in human and rat pituitary somatotrophs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Adrenomedullin and the control of fluid and electrolyte homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Proadrenomedullin-derived peptides in the paracrine control of the hypothalamo-pituitary-adrenal axis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Expression of the adrenomedullin binding protein, complement factor H, in the pancreas and its physiological impact on insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Regulation of pancreatic physiology by adrenomedullin and its binding protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Expression of proadrenomedullin derived peptides in the mammalian pituitary: co-localization of follicle stimulating hormone and proadrenomedullin N-20 terminal peptide-like peptide in the same secretory granules of the gonadotropes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Adrenomedullin inhibits hypoxic cell death by upregulation of Bcl-2 in endometrial cancer cells: a possible promotion mechanism for tumour growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Induction of max by adrenomedullin and calcitonin gene-related peptide antagonizes endothelial apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Systemic administration of adrenomedullin(27-52) increases bone volume and strength in male mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

RAMPs and CRLR expressions in osteoblastic cells after dexamethasone treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Human adrenomedullin gene delivery protects against cardiac hypertrophy, fibrosis, and renal damage in hypertensive dahl salt-sensitive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Long-term adrenomedullin infusion improves survival in malignant hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Hemodynamic effects of a novel hypotensive peptide, human adrenomedullin, in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Biological and clinical roles of adrenomedullin in circulation control and cardiovascular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Vasodilator mRNA levels are increased in the livers of portal hypertensive NO-synthase 3-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Plasma adrenomedullin levels in patients with non-insulin dependent diabetes mellitus: close relationships with diabetic complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Levels of plasma total adrenomedullin are related with two acute phase inflammatory reactants (fibrinogen and sialic acid) but not with markers of endothelial dysfunction in Type 1 diabetes Adrenomedullin and vascular risk factors in Type 1 DM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Organ-protective effects of adrenomedullin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Review of diabetes: identification of markers for early detection, glycemic control, and monitoring clinical complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Deficiency of adrenomedullin induces insulin resistance by increasing oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Adrenomedullin and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Adrenomedullin expression in human tumor cell lines. Its potential role as an autocrine growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Adrenomedullin prevents apoptosis in prostate cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Adrenomedullin inhibits prostate cancer cell proliferation through a cAMP-independent autocrine mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Presence of immunoreactive adrenomedullin in human and bovine milk

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Adrenomedullin promotes formation of xenografted endometrial tumors by stimulation of autocrine growth and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Effects of adrenomedullin on endothelial cells in the multistep process of angiogenesis: involvement of CRLR/RAMP2 and CRLR/RAMP3 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Adrenomedullin gene transfer induces therapeutic angiogenesis in a rabbit model of chronic hind limb ischemia: benefits of a novel nonviral vector, gelatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

The role of adrenomedullin in angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Hypoxia-inducible factor-1 (HIF-1) up-regulates adrenomedullin expression in human tumor cell lines during oxygen deprivation: a possible promotion mechanism of carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Adrenomedullin antagonist suppresses in vivo growth of human pancreatic cancer cells in SCID mice by suppressing angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Gastroprotective effect of adrenomedullin administered subcutaneously in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Secretory and vascular effects of adrenomedullin in gastric ulcer: role of CGRP- and adrenomedullin-receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Differential gene expression of adrenomedullin receptors in pressure- and volume-overloaded heart--role of angiotensin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

The proinflammatory cytokine interleukin 1beta and hypoxia cooperatively induce the expression of adrenomedullin in ovarian carcinoma cells through hypoxia inducible factor 1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Angiotensin II stimulates cardiac adrenomedullin production and causes accumulation of mature adrenomedullin independently of hemodynamic stress in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Regulation of adrenomedullin gene transcription and degradation by the c-myc gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Progesterone upregulates calcitonin gene-related peptide and adrenomedullin receptor components and cyclic adenosine 3'5'-monophosphate generation in Eker rat uterine smooth muscle cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Matrix metalloproteinase-2 cleavage of adrenomedullin produces a vasoconstrictor out of a vasodilator

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Synthesis, biological evaluation, and three-dimensional quantitative structure-activity relationship study of small-molecule positive modulators of adrenomedullin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Identification of vasoactive nonpeptidic positive and negative modulators of adrenomedullin using a neutralizing antibody-based screening strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Adrenomedullin and total nitrite levels in children with acute rheumatic fever

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Identification of novel adrenomedullin in mammals: a potent cardiovascular and renal regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Haemodynamic and hormonal effects of adrenomedullin in patients with pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

Adrenomedullin is a cross-talk molecule that regulates tumor and mast cell function during human carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.2.303

10.1517/14728222.10.2.303

21 January 2018

Identifiers

DOI

1 reference

14 August 2017

1 reference