(Q36429021)

14 August 2017

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title

Mechanisms of angiogenesis in gliomas (English)

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14 August 2017

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Kargiotis O

1

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PubMed ID

16554966

14 August 2017

Rao JS

series ordinal

2

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PubMed ID

16554966

14 August 2017

Kyritsis AP

series ordinal

3

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14 August 2017

23 March 2006

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Journal of Neuro-Oncology

14 August 2017

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14 August 2017

78

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14 August 2017

281-293

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14 August 2017

3

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https://scigraph.springernature.com/pub.10.1007/s11060-005-9097-6

14 August 2017

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cites work

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The WHO classification of tumors of the nervous system

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The functional role of tumor suppressor genes in gliomas: clues for future therapeutic strategies

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Glomeruloid microvascular proliferation orchestrated by VPF/VEGF: a new world of angiogenesis research

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Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

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Up-regulation of macrophage migration inhibitory factor gene and protein expression in glial tumor cells during hypoxic and hypoglycemic stress indicates a critical role for angiogenesis in glioblastoma multiforme

21 January 2018

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The von Hippel-Lindau tumor suppressor gene product interacts with Sp1 to repress vascular endothelial growth factor promoter activity

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11060-005-9097-6

Platelet-derived growth factor-B enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment

21 January 2018

1 reference

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Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: a model of glioblastoma multiforme pathophysiology

21 January 2018

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Dual pathways of tubular morphogenesis of vascular endothelial cells by human glioma cells: vascular endothelial growth factor/basic fibroblast growth factor and interleukin-8.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11060-005-9097-6

Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors

21 January 2018

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Mitogenesis, cell migration, and loss of focal adhesions induced by tenascin-C interacting with its cell surface receptor, annexin II.

21 January 2018

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Requirement of vascular integrin alpha v beta 3 for angiogenesis

21 January 2018

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12 December 2020

The tenascin family of ECM glycoproteins: structure, function, and regulation during embryonic development and tissue remodeling

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12 December 2020

Interleukin-8 as a macrophage-derived mediator of angiogenesis

1 reference

12 December 2020

Vascular endothelial growth factor receptor-2 and neuropilin-1 form a receptor complex that is responsible for the differential signaling potency of VEGF(165) and VEGF(121)

1 reference

12 December 2020

Endothelial cell hyperplasia in human glioblastoma: coexpression of mRNA for platelet-derived growth factor (PDGF) B chain and PDGF receptor suggests autocrine growth stimulation

1 reference

12 December 2020

Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas

1 reference

12 December 2020

Expression of functional formyl peptide receptors by human astrocytoma cell lines.

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12 December 2020

Invasion as limitation to anti-angiogenic glioma therapy

1 reference

12 December 2020

The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis

1 reference

12 December 2020

Platelet-Derived Growth Factor is AngiogenicIn Vivo

1 reference

12 December 2020

Detection of tumor necrosis factor-α protein and messenger RNA in human glial brain tumors: comparison of immunohistochemistry with in situ hybridization using molecular probes

1 reference

12 December 2020

Early and extensive contribution of pericytes/vascular smooth muscle cells to microvascular proliferation in glioblastoma multiforme: an immuno-light and immuno-electron microscopic study.

1 reference

12 December 2020

Hepatocyte growth factor is associated with poor prognosis of malignant gliomas and is a predictor for recurrence of meningioma.

1 reference

12 December 2020

Up-regulation of vascular endothelial growth factor by membrane-type 1 matrix metalloproteinase stimulates human glioma xenograft growth and angiogenesis.

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12 December 2020

The role of plasminogen activators in the regulation of connective tissue metalloproteinases

1 reference

12 December 2020

Induction of vascular endothelial growth factor expression in endothelial cells by platelet-derived growth factor through the activation of phosphatidylinositol 3-kinase.

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12 December 2020

Genetic and hypoxic regulation of angiogenesis in gliomas

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12 December 2020

Transforming growth factor-beta inhibits endothelial cell proliferation

1 reference

12 December 2020

Phorbol ester activation of a proteolytic cascade capable of activating latent transforming growth factor-betaL a process initiated by the exocytosis of cathepsin B.

1 reference

12 December 2020

Heparan sulfate proteoglycans as regulators of fibroblast growth factor-2 signaling in brain endothelial cells. Specific role for glypican-1 in glioma angiogenesis

1 reference

12 December 2020

Correlation of endothelin-1 and transforming growth factor beta 1 with malignancy and vascularity in human gliomas.

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12 December 2020

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly

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12 December 2020

Vascular endothelial growth factor up-regulates its receptor fms-like tyrosine kinase 1 (FLT-1) and a soluble variant of FLT-1 in human vascular endothelial cells

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12 December 2020

Expression and localization of urokinase-type plasminogen activator in human astrocytomas in vivo.

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12 December 2020

SB-431542, a small molecule transforming growth factor-beta-receptor antagonist, inhibits human glioma cell line proliferation and motility.

1 reference

12 December 2020

Get a ligand, get a life: integrins, signaling and cell survival

1 reference

12 December 2020

RNAi-mediated inhibition of cathepsin B and uPAR leads to decreased cell invasion, angiogenesis and tumor growth in gliomas.

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12 December 2020

Vascular endothelial growth factor production is stimulated by gangliosides and TGF-beta isoforms in human glioma cells in vitro

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12 December 2020

Neoplastic cells and proliferating endothelial cells express connective tissue growth factor (CTGF) in glioblastoma.

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12 December 2020

CXCL12 in malignant glial tumors: a possible role in angiogenesis and cross-talk between endothelial and tumoral cells.

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12 December 2020

The fibroblast growth factor family: structural and biological properties

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12 December 2020

Fas engagement increases expression of interleukin-6 in human glioma cells

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12 December 2020

Phosphatidylinositol 3'-kinase and MAPK/ERK kinase 1/2 differentially regulate expression of vascular endothelial growth factor in human malignant astrocytoma cells

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12 December 2020

Expression of an altered epidermal growth factor receptor by human glioblastoma cells

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12 December 2020

Vascular endothelial growth factor in human glioma cell lines: induced secretion by EGF, PDGF-BB, and bFGF.

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12 December 2020

Connective tissue growth factor induces the proliferation, migration, and tube formation of vascular endothelial cells in vitro, and angiogenesis in vivo

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12 December 2020

Integrins, angiogenesis and vascular cell survival

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12 December 2020

Expression and localization of 92 kDa type IV collagenase/gelatinase B (MMP-9) in human gliomas.

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12 December 2020

Stimulation of angiogenesis through cathepsin B inactivation of the tissue inhibitors of matrix metalloproteinases

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12 December 2020

Tumour-endothelium interactions in co-culture: coordinated changes of gene expression profiles and phenotypic properties of endothelial cells.

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12 December 2020

Inhibition of matrix metalloproteinase-9 reduces in vitro invasion and angiogenesis in human microvascular endothelial cells

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12 December 2020

Macrophage migration inhibitory factor (MIF) expression in human glioblastomas correlates with vascular endothelial growth factor (VEGF) expression.

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12 December 2020

Basic fibroblast growth factor-like activity and receptors are expressed in a human glioma cell line

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12 December 2020

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

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12 December 2020

Dual role of tumor necrosis factor-alpha in angiogenesis

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12 December 2020

Transforming growth factor-beta and Ras regulate the VEGF/VEGF-receptor system during tumor angiogenesis.

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12 December 2020

Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo

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12 December 2020

CYR61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth

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12 December 2020

Levels of expression of CYR61 and CTGF are prognostic for tumor progression and survival of individuals with gliomas

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12 December 2020

Current perspectives on antiangiogenesis strategies in the treatment of malignant gliomas

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12 December 2020

Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning

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12 December 2020

Binding of urokinase-type plasminogen activator to its receptor in MCF-7 cells activates extracellular signal-regulated kinase 1 and 2 which is required for increased cellular motility

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12 December 2020

Interleukin-6 overexpression as a marker of malignancy in human gliomas.

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12 December 2020

Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

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12 December 2020

Focal adhesion kinase is expressed in the angiogenic blood vessels of malignant astrocytic tumors in vivo and promotes capillary tube formation of brain microvascular endothelial cells.

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12 December 2020

Acidic and basic fibroblast growth factors are present in glioblastoma multiforme

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12 December 2020

Ero1-L alpha plays a key role in a HIF-1-mediated pathway to improve disulfide bond formation and VEGF secretion under hypoxia: implication for cancer

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12 December 2020

Enhanced expression of transforming growth factor-beta and its type-I and type-II receptors in human glioblastoma.

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12 December 2020

Tenascin-C promotes microvascular cell migration and phosphorylation of focal adhesion kinase.

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12 December 2020

Blockade of cathepsin B expression in human glioblastoma cells is associated with suppression of angiogenesis

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12 December 2020

The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing

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12 December 2020

Regulation of astrocytic tenascin by basic fibroblast growth factor

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12 December 2020

Effects of tumor suppressor gene (p53) on brain tumor angiogenesis and expression of angiogenic modulators.

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12 December 2020

Vaso-occlusive and prothrombotic mechanisms associated with tumor hypoxia, necrosis, and accelerated growth in glioblastoma

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12 December 2020

Characterization and expression of a novel alternatively spliced human angiopoietin-2

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12 December 2020

Regulation of interleukin-8 expression by reduced oxygen pressure in human glioblastoma

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12 December 2020

Insulin-like growth factor-1 content and pattern of expression correlates with histopathologic grade in diffusely infiltrating astrocytomas

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12 December 2020

The Jak/Stat pathway and urokinase receptor signaling in human aortic vascular smooth muscle cells.

1 reference

12 December 2020

Control of type IV collagenase activity by components of the urokinase-plasmin system: a regulatory mechanism with cell-bound reactants.

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12 December 2020

Angiogenesis and apoptosis in glioma: two arenas for promising new therapies

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12 December 2020

What Is the Evidence That Tumors Are Angiogenesis Dependent?

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12 December 2020

Human glioblastoma cells release interleukin 6 in vivo and in vitro

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12 December 2020

IkappaBalphaM suppresses angiogenesis and tumorigenesis promoted by a constitutively active mutant EGFR in human glioma cells

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12 December 2020

Sp1 recognition sites in the proximal promoter of the human vascular endothelial growth factor gene are essential for platelet-derived growth factor-induced gene expression

1 reference

12 December 2020

Tenascin: cDNA cloning and induction by TGF-beta

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12 December 2020

Mechanisms underlying PTEN regulation of vascular endothelial growth factor and angiogenesis

1 reference

12 December 2020

Angiogenesis by fibroblast growth factor 4 is mediated through an autocrine up-regulation of vascular endothelial growth factor expression.

1 reference

12 December 2020

Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.

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12 December 2020

Alpha(v)beta3 and alpha(v)beta5 integrin expression in glioma periphery.

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12 December 2020

Vascular endothelial growth factor increases release of gelatinase A and decreases release of tissue inhibitor of metalloproteinases by microvascular endothelial cells in vitro

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12 December 2020

Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF.

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12 December 2020

Interleukin-8 stimulates angiogenesis in rats

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12 December 2020

Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells

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12 December 2020

Interleukin-8 is produced in neoplastic and infectious diseases of the human central nervous system.

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12 December 2020

Influence of VEGF-R2 inhibition on MMP secretion and motility of microvascular human cerebral endothelial cells (HCEC).

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12 December 2020

Distribution of endogenous tumour necrosis factor alpha in gliomas

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12 December 2020

Purification of a factor from human placenta that stimulates capillary endothelial cell protease production, DNA synthesis, and migration.

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12 December 2020

Interleukin 6 induces the expression of vascular endothelial growth factor

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12 December 2020

Antiangiogenesis -- therapeutic strategies and clinical implications for brain tumors

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12 December 2020

Expression and localization of scatter factor/hepatocyte growth factor in human astrocytomas

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12 December 2020

Expression of cathepsin B and microvascular density increases with higher grade of astrocytomas.

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12 December 2020

Mutant IkappaBalpha suppresses hypoxia-induced VEGF expression through downregulation of HIF-1alpha and COX-2 in human glioma cells.

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12 December 2020

Proteases and the biology of glioma invasion

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12 December 2020

Enhanced tumorigenic behavior of glioblastoma cells expressing a truncated epidermal growth factor receptor is mediated through the Ras-Shc-Grb2 pathway

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12 December 2020

Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis

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12 December 2020

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12 December 2020

Growth factors in glioma angiogenesis: FGFs, PDGF, EGF, and TGFs

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12 December 2020

The effects of type beta transforming growth factor on proliferation and epidermal growth factor receptor expression in a human glioblastoma cell line

1 reference

12 December 2020

Expression of angiogenic growth factor genes in primary human astrocytomas may contribute to their growth and progression.

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12 December 2020

Inhibition of cathepsin B and MMP-9 gene expression in glioblastoma cell line via RNA interference reduces tumor cell invasion, tumor growth and angiogenesis.

1 reference

12 December 2020

Interleukin-6 induces transcriptional activation of vascular endothelial growth factor (VEGF) in astrocytes in vivo and regulates VEGF promoter activity in glioblastoma cells via direct interaction between STAT3 and Sp1.

1 reference

12 December 2020

MT1-MMP initiates activation of pro-MMP-2 and integrin alphavbeta3 promotes maturation of MMP-2 in breast carcinoma cells

1 reference

12 December 2020

Cyr61 and Fisp12 are both ECM-associated signaling molecules: activities, metabolism, and localization during development

1 reference

12 December 2020

Normoxic and hypoxic regulation of vascular endothelial growth factor (VEGF) by astrocytoma cells is mediated by Ras.

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12 December 2020

Wild-type p53 suppresses angiogenesis in human leiomyosarcoma and synovial sarcoma by transcriptional suppression of vascular endothelial growth factor expression

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12 December 2020

The effects of exogenous growth factors on matrix metalloproteinase secretion by human brain tumour cells

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12 December 2020

Correlation of p53 immunoreactivity and sequencing in patients with glioma.

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12 December 2020

Induction of vascular endothelial growth factor by tumor necrosis factor alpha in human glioma cells. Possible roles of SP-1.

1 reference

12 December 2020

Matrix metalloproteinases regulate neovascularization by acting as pericellular fibrinolysins

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12 December 2020

Malignant glioma biology: role for TGF-beta in growth, motility, angiogenesis, and immune escape

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12 December 2020

Vascular endothelial growth factor is a secreted angiogenic mitogen

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12 December 2020

Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis

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12 December 2020

Transforming growth factors beta(1) (TGF-beta(1)) and TGF-beta(2) promote glioma cell migration via Up-regulation of alpha(V)beta(3) integrin expression.

1 reference

12 December 2020

Macrophage infiltration-associated thymidine phosphorylase expression correlates with increased microvessel density and poor prognosis in astrocytic tumors

1 reference

12 December 2020

Tumor necrosis factor alpha induces angiogenic factor up-regulation in malignant glioma cells: a role for RNA stabilization and HuR.

1 reference

12 December 2020

Levels of vascular endothelial growth factor, hepatocyte growth factor/scatter factor and basic fibroblast growth factor in human gliomas and their relation to angiogenesis.

1 reference

12 December 2020

Pro-angiogenic activities of CYR61 (CCN1) mediated through integrins alphavbeta3 and alpha6beta1 in human umbilical vein endothelial cells.

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12 December 2020

Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo.

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12 December 2020

Tenascin-C expression by angiogenic vessels in human astrocytomas and by human brain endothelial cells in vitro

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12 December 2020

Expression and regulation patterns of hyaluronidases in small cell lung cancer and glioma lines

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12 December 2020

The NG2 chondroitin sulfate proteoglycan: role in malignant progression of human brain tumours

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12 December 2020

The role of angiogenesis in tumor growth

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12 December 2020

Specific interference of urokinase-type plasminogen activator receptor and matrix metalloproteinase-9 gene expression induced by double-stranded RNA results in decreased invasion, tumor growth, and angiogenesis in gliomas.

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12 December 2020

NG2 proteoglycan promotes angiogenesis-dependent tumor growth in CNS by sequestering angiostatin.

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12 December 2020

Regulation of cell invasion and morphogenesis in a three-dimensional type I collagen matrix by membrane-type matrix metalloproteinases 1, 2, and 3.

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12 December 2020

Expression and localization of urokinase-type plasminogen activator receptor in human gliomas.

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12 December 2020

Formylpeptide receptor FPR and the rapid growth of malignant human gliomas

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12 December 2020

Angiogenic effect of thymidine phosphorylase on macrophages in glioblastoma multiforme

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12 December 2020

Microvessel density is a prognostic indicator for patients with astroglial brain tumors.

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12 December 2020

In vivo targeting of SF/HGF and c-met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis.

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12 December 2020

Inhibition of intracerebral glioblastoma growth by local treatment with the scatter factor/hepatocyte growth factor-antagonist NK4.

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12 December 2020

Inhibition of angiogenesis in human glioma cell lines by antisense RNA from the soluble guanylate cyclase genes, GUCY1A3 and GUCY1B3.

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12 December 2020

Endothelial cell attachment and spreading on human tenascin is mediated by alpha 2 beta 1 and alpha v beta 3 integrins

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12 December 2020

Transforming growth factor-beta-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines

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12 December 2020

Mechanism of action and in vivo role of platelet-derived growth factor

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12 December 2020

Focus on central nervous system neoplasia

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12 December 2020

Glioma cell invasion: regulation of metalloproteinase activity by TGF-beta.

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12 December 2020

Glioblastoma and cerebral microvascular endothelial cell migration in response to tumor-associated growth factors.

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12 December 2020

Tumor necrosis factor activates human endothelial cells through the p55 tumor necrosis factor receptor but the p75 receptor contributes to activation at low tumor necrosis factor concentration

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12 December 2020

Versican/PG-M G3 domain promotes tumor growth and angiogenesis

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12 December 2020

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12 December 2020

Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis

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12 December 2020

Upregulation of interleukin 8 by oxygen-deprived cells in glioblastoma suggests a role in leukocyte activation, chemotaxis, and angiogenesis

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12 December 2020

Immunolocalization of cathepsin B in human glioma: implications for tumor invasion and angiogenesis

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12 December 2020

Signal transduction pathways and their relevance in human astrocytomas

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12 December 2020

Degradation of extracellular matrix protein tenascin-C by cathepsin B: an interaction involved in the progression of gliomas

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12 December 2020

Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops

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12 December 2020

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

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12 December 2020

The alpha v beta 3 integrin "vitronectin receptor"

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12 December 2020

Epidermal growth factor receptor transcriptionally up-regulates vascular endothelial growth factor expression in human glioblastoma cells via a pathway involving phosphatidylinositol 3'-kinase and distinct from that induced by hypoxia.

1 reference

12 December 2020

Tenascin expression in astrocytomas correlates with angiogenesis

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12 December 2020

VEGF121 induces proliferation of vascular endothelial cells and expression of flk-1 without affecting lymphatic vessels of chorioallantoic membrane.

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12 December 2020

Definition of Two Angiogenic Pathways by Distinct alpha(v) Integrins

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12 December 2020

Signal transduction to hypoxia-inducible factor 1

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12 December 2020

Multistep nature of microvascular recruitment of ex vivo-expanded embryonic endothelial progenitor cells during tumor angiogenesis

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12 December 2020

Expression of angiopoietin-2 in human glioma cells and its role for angiogenesis.

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12 December 2020

PTEN mutation and epidermal growth factor receptor activation regulate vascular endothelial growth factor (VEGF) mRNA expression in human glioblastoma cells by transactivating the proximal VEGF promoter.

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12 December 2020

Deletion of p16 and p15 genes in brain tumors

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12 December 2020

Transforming growth factor beta1 induces angiogenesis in vivo with a threshold pattern

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12 December 2020

Activation-dependent adhesion of human platelets to Cyr61 and Fisp12/mouse connective tissue growth factor is mediated through integrin alpha(IIb)beta(3)

1 reference

12 December 2020

10.1007/S11060-005-9097-6

Identifiers

DOI

1 reference

14 August 2017

1 reference

PubMed ID

16554966