(Q36429535)

14 August 2017

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title

Notch signaling in T-cell acute lymphoblastic leukemia (English)

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14 August 2017

lymphoblastic leukemia

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Andrew P Weng

1

1 reference

PubMed ID

16556027

14 August 2017

Arthur Lau

series ordinal

2

1 reference

PubMed ID

16556027

14 August 2017

language of work or name

English

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publication date

1 August 2005

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14 August 2017

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14 August 2017

1

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14 August 2017

511-519

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14 August 2017

4

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Childhood T-Cell Acute Lymphoblastic Leukemia: The Dana-Farber Cancer Institute Acute Lymphoblastic Leukemia Consortium Experience

14 August 2017

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Cytogenetics and molecular genetics of acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Analysis of TCR, pT alpha, and RAG-1 in T-acute lymphoblastic leukemias improves understanding of early human T-lymphoid lineage commitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Clinical and biological importance of cytogenetic abnormalities in childhood and adult acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Notch, a unifying target in T-cell acute lymphoblastic leukemia?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Presenilin is required for activity and nuclear access of Notch in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

The suppressor of hairless protein participates in notch receptor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Suppressor of Hairless, the Drosophila homolog of the mouse recombination signal-binding protein gene, controls sensory organ cell fates

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Signalling downstream of activated mammalian Notch

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

A histone deacetylase corepressor complex regulates the Notch signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Functional interaction between the mouse notch1 intracellular region and histone acetyltransferases PCAF and GCN5

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complex

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Notch subunit heterodimerization and prevention of ligand-independent proteolytic activation depend, respectively, on a novel domain and the LNR repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Notch signaling in lymphopoiesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Separation of Notch1 promoted lineage commitment and expansion/transformation in developing T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Notch inhibition of E47 supports the existence of a novel signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Notch-induced E2A ubiquitination and degradation are controlled by MAP kinase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Pre-TCR-triggered ERK signalling-dependent downregulation of E2A activity in Notch3-induced T-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

TAL1/SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Notch ligands Delta 1 and Jagged1 transmit distinct signals to T-cell precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

The role of Notch and IL-7 signaling in early thymocyte proliferation and differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

The Anti-apoptotic Effect of Notch-1 Requires p56 -dependent, Akt/PKB-mediated Signaling in T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Two distinct Notch1 mutant alleles are involved in the induction of T-cell leukemia in c-myc transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Perturbation of Ikaros isoform selection by MLV integration is a cooperative event in Notch(IC)-induced T cell leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Function and dysfunction of the presenilins

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

The Role of presenilins in gamma-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Notch1 expression in early lymphopoiesis influences B versus T lineage determination.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

The BAL-binding protein BBAP and related Deltex family members exhibit ubiquitin-protein isopeptide ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

c-Cbl binding and ubiquitin-dependent lysosomal degradation of membrane-associated Notch1.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Mastermind critically regulates Notch-mediated lymphoid cell fate decisions.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Neoplastic transformation by Notch requires nuclear localization

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Notch4 inhibits endothelial apoptosis via RBP-Jkappa-dependent and -independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Comparative analysis of the human and mouse Hey1 promoter: Hey genes are new Notch target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Correlating notch signaling with thymocyte maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Presenilin-dependent gamma-secretase activity modulates thymocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Adipsin, a biomarker of gastrointestinal toxicity mediated by a functional gamma-secretase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/E7 expression and late steps of malignant transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

HPV16 E6 and E7 oncoproteins regulate Notch-1 expression and cooperate to induce transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Activated Notch1 inhibits p53-induced apoptosis and sustains transformation by human papillomavirus type 16 E6 and E7 oncogenes through a PI3K-PKB/Akt-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

JAGGED1 expression is associated with prostate cancer metastasis and recurrence

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Jagged1-induced Notch signaling drives proliferation of multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Overexpression of the NOTCH ligand JAG2 in malignant plasma cells from multiple myeloma patients and cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Notch2 is involved in the overexpression of CD23 in B-cell chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Delta4, an endothelial specific notch ligand expressed at sites of physiological and tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

New molecular pathways in angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Constitutively active Notch4 promotes early human hematopoietic progenitor cell maintenance while inhibiting differentiation and causes lymphoid abnormalities in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Involvement of the TCL5 gene on human chromosome 1 in T-cell leukemia and melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Deregulation of a Homeobox Gene, HOX11, by the t(10;14) in T Cell Leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

A new recurrent and specific cryptic translocation, t(5;14)(q35;q32), is associated with expression of the Hox11L2 gene in T acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Various types of rearrangements target TLX3 locus in T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

CALM-AF10 is a common fusion transcript in T-ALL and is specific to the TCRgammadelta lineage.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Identification and molecular characterization of CALM/AF10fusion products in T cell acute lymphoblastic leukemia and acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

The LCK gene is involved in the t(1;7)(p34;q34) in the T-cell acute lymphoblastic leukemia derived cell line, HSB-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

Molecular analysis of the t(8;14)(q24;q11) chromosomal breakpoint junctions in the T-cell leukemia line MOLT-16.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.4.511

21 January 2018

Identifiers

DOI

10.2217/14796694.1.4.511

1 reference

14 August 2017

1 reference

PubMed ID

16556027