(Q36433765)

14 August 2017

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title

Update of research and management of hepatitis B. (English)

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14 August 2017

Takeshi Okanoue

1

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PubMed ID

16568369

14 August 2017

Masahito Minami

series ordinal

2

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PubMed ID

16568369

14 August 2017

language of work or name

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1 February 2006

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Journal of Gastroenterology

14 August 2017

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14 August 2017

41

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14 August 2017

2

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14 August 2017

107-118

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A new genotype of hepatitis B virus: complete genome and phylogenetic relatedness

14 August 2017

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https://api.crossref.org/works/10.1007%2FS00535-006-1774-5

Genotype H: a new Amerindian genotype of hepatitis B virus revealed in Central America

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00535-006-1774-5

Wild-type levels of pregenomic RNA and replication but reduced pre-C RNA and e-antigen synthesis of hepatitis B virus with C(1653) --> T, A(1762) --> T and G(1764) --> A mutations in the core promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-006-1774-5

Hepatitis B virus strains with mutations in the core promoter in patients with fulminant hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-006-1774-5

Lamivudine and alpha-interferon in combination long term for precore mutant chronic hepatitis B.

21 January 2018

1 reference

12 December 2020

Hepatitis B virus genotypes and hepatocellular carcinoma in Japan

1 reference

12 December 2020

Lamivudine therapy for chronic hepatitis B: a six-month randomized dose-ranging study

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12 December 2020

Clinical outcome and virologic profiles of severe hepatitis B exacerbation due to YMDD mutations.

1 reference

12 December 2020

Hepatitis B virus DNA integration in a sequence homologous to v-erb-A and steroid receptor genes in a hepatocellular carcinoma

1 reference

12 December 2020

Outcome of anti-HBe positive chronic hepatitis B in alpha-interferon treated and untreated patients: a long term cohort study

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12 December 2020

Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B.

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12 December 2020

Prediction of breakthrough hepatitis due to lamivudine-resistant hepatitis B virus by a sensitive semiquantitative assay using peptide nucleic acids

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12 December 2020

Identification of human cancer-related genes by naturally occurring Hepatitis B Virus DNA tagging

1 reference

12 December 2020

Common sites of retroviral integration in mouse hematopoietic tumors identified by high-throughput, single nucleotide polymorphism-based mapping and bacterial artificial chromosome hybridization

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12 December 2020

Effect of Alpha-Interferon Treatment in Patients with Hepatitis B e Antigen-Positive Chronic Hepatitis B

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12 December 2020

Peginterferon-alpha-2a (40 kD): a review of its use in the management of chronic hepatitis C.

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12 December 2020

Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse

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12 December 2020

Detection of YMDD mutant using a novel sensitive method in chronic liver disease type B patients before and during lamivudine treatment

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12 December 2020

A one-year trial of lamivudine for chronic hepatitis B. Asia Hepatitis Lamivudine Study Group.

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12 December 2020

Hepatitis B virus pre-S2 mutant upregulates cyclin A expression and induces nodular proliferation of hepatocytes.

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12 December 2020

Entecavir is superior to lamivudine in reducing hepatitis B virus DNA in patients with chronic hepatitis B infection.

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12 December 2020

Long-term entecavir treatment results in sustained antiviral efficacy and prolonged life span in the woodchuck model of chronic hepatitis infection.

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12 December 2020

Long-term follow-up of peginterferon and lamivudine combination treatment in HBeAg-positive chronic hepatitis B.

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12 December 2020

Hepatitis B virus genotypes and spontaneous hepatitis B e antigen seroconversion in Taiwanese hepatitis B carriers

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12 December 2020

Long-term beneficial effect of interferon therapy in patients with chronic hepatitis B virus infection

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12 December 2020

Rorgamma (Rorc) is a common integration site in type B leukemogenic virus-induced T-cell lymphomas

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12 December 2020

Fulminant hepatitis B: induction by hepatitis B virus mutants defective in the precore region and incapable of encoding e antigen

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12 December 2020

Hepatitis B virus genotype A rarely circulates as an HBe-minus mutant: possible contribution of a single nucleotide in the precore region.

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12 December 2020

Lamivudine and alpha interferon combination treatment of patients with chronic hepatitis B infection: a randomised trial

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12 December 2020

Pretherapy alanine transaminase level as a determinant for hepatitis B e antigen seroconversion during lamivudine therapy in patients with chronic hepatitis B. Asian Hepatitis Lamivudine Trial Group

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12 December 2020

Infection with hepatitis B virus genotype A in Tokyo, Japan during 1976 through 2001.

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12 December 2020

Fulminant hepatitis B in successive female sexual partners of two anti-HBe-positive males.

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12 December 2020

Adefovir dipivoxil alone or in combination with lamivudine in patients with lamivudine-resistant chronic hepatitis B.

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12 December 2020

Hepatitis B e antigen seroconversion after lamivudine therapy is not durable in patients with chronic hepatitis B in Korea

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12 December 2020

HBV core promoter mutations prevail in patients with hepatocellular carcinoma from Guangxi, China

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12 December 2020

Acute hepatitis B in infants born to carrier mother with the antibody to hepatitis B e antigen

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12 December 2020

Adefovir dipivoxil added to ongoing lamivudine in chronic hepatitis B with YMDD mutant hepatitis B virus

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12 December 2020

A function of the hepatitis B virus precore protein is to regulate the immune response to the core antigen

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12 December 2020

Biological impact of natural COOH-terminal deletions of hepatitis B virus X protein in hepatocellular carcinoma tissues.

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12 December 2020

Specific mutations of hepatitis B virus in plasma predict liver cancer development

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12 December 2020

Replication of the wild type and a natural hepatitis B virus nucleocapsid promoter variant is differentially regulated by nuclear hormone receptors in cell culture.

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12 December 2020

Clinical features of hepatitis B virus genotype A in Japanese patients.

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12 December 2020

Influence of hepatitis B virus genotypes on the progression of chronic type B liver disease

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12 December 2020

New genes involved in cancer identified by retroviral tagging

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12 December 2020

A case-control study for clinical and molecular biological differences between hepatitis B viruses of genotypes B and C. Japan HBV Genotype Research Group

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12 December 2020

A 3-year clinical trial of lamivudine in treatment of patients with chronic hepatitis B.

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12 December 2020

Clinical relevance of hepatitis B virus genotype in children with chronic infection and hepatocellular carcinoma

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12 December 2020

Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice

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12 December 2020

Geographic distribution of hepatitis B virus (HBV) genotype in patients with chronic HBV infection in Japan

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12 December 2020

Lamivudine/interferon combination therapy in anti-HBe positive chronic hepatitis B patients: a controlled pilot study

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12 December 2020

High prevalence of 1762(T) 1764(A) mutations in the basic core promoter of hepatitis B virus isolated from black Africans with hepatocellular carcinoma compared with asymptomatic carriers.

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12 December 2020

Pathogenesis of hepatitis B virus-related hepatocellular carcinoma: old and new paradigms

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12 December 2020

Lamivudine as initial treatment for chronic hepatitis B in the United States

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12 December 2020

Distinct modes of regulation of transcription of hepatitis B virus by the nuclear receptors HNF4alpha and COUP-TF1

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12 December 2020

Resistance to adefovir dipivoxil therapy associated with the selection of a novel mutation in the HBV polymerase

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12 December 2020

Familial risk of hepatocellular carcinoma among chronic hepatitis B carriers and their relatives

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12 December 2020

Interferon monotherapy in chronic hepatitis B.

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12 December 2020

cis-Activation of the human telomerase gene (hTERT) by the hepatitis B virus genome

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12 December 2020

Effects of a naturally occurring mutation in the hepatitis B virus basal core promoter on precore gene expression and viral replication

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12 December 2020

A 1-year trial of telbivudine, lamivudine, and the combination in patients with hepatitis B e antigen-positive chronic hepatitis B

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12 December 2020

Peginterferon alpha-2a (40 kDa): an advance in the treatment of hepatitis B e antigen-positive chronic hepatitis B.

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12 December 2020

Mutations in the pre-core region of hepatitis B virus serve to enhance the stability of the secondary structure of the pre-genome encapsidation signal

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12 December 2020

Typing hepatitis B virus by homology in nucleotide sequence: comparison of surface antigen subtypes

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12 December 2020

Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B

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12 December 2020

Hepatitis B virus integration in a cyclin A gene in a hepatocellular carcinoma

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12 December 2020

HBx gene of hepatitis B virus induces liver cancer in transgenic mice

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12 December 2020

Identification and characterization of a prevalent hepatitis B virus X protein mutant in Taiwanese patients with hepatocellular carcinoma

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12 December 2020

Hot-spot mutations in hepatitis B virus X gene in hepatocellular carcinoma

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12 December 2020

A randomized, controlled trial of a 24-month course of interferon alfa 2b in patients with chronic hepatitis B who had hepatitis B virus DNA without hepatitis B e antigen in serum

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12 December 2020

Hepatitis B virus genotype distribution among chronic hepatitis B virus carriers in Shanghai, China

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12 December 2020

A hepatitis B virus mutant associated with an epidemic of fulminant hepatitis

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12 December 2020

Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B

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12 December 2020

A pilot study of beta-interferon for treatment of patients with chronic hepatitis B who failed to respond to alpha-interferon

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12 December 2020

Adefovir dipivoxil for the treatment of hepatitis B e antigen-negative chronic hepatitis B.

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12 December 2020

Modification of cyclin A expression by hepatitis B virus DNA integration in a hepatocellular carcinoma

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12 December 2020

Significance of pre-S region-defective hepatitis B virus that emerged during exacerbation of chronic type B hepatitis

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12 December 2020

Hepatitis B virus genotypes in the United States: results of a nationwide study

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12 December 2020

Lamivudine and 24 weeks of lamivudine/interferon combination therapy for hepatitis B e antigen-positive chronic hepatitis B in interferon nonresponders.

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12 December 2020

Hepatitis B virus-related insertional mutagenesis in chronic hepatitis B patients as an early drastic genetic change leading to hepatocarcinogenesis

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12 December 2020

Comparison of envelope and precore/core variants of hepatitis B virus (HBV) during chronic HBV infection

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12 December 2020

Comparison of adefovir and tenofovir in the treatment of lamivudine-resistant hepatitis B virus infection

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12 December 2020

Interferon alfa for chronic hepatitis B infection: Increased efficacy of prolonged treatment

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12 December 2020

Analysis of integration sites of Jaagsiekte sheep retrovirus in ovine pulmonary adenocarcinoma

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12 December 2020

Core promoter mutations and genotypes in relation to viral replication and liver damage in East Asian hepatitis B virus carriers

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12 December 2020

PreS1 deleted variants of hepatitis B virus in patients with chronic hepatitis

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12 December 2020

Mutations of polymerase, precore and core promoter gene in hepatitis B virus during 5-year lamivudine therapy

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12 December 2020

Difference in prognosis between patients infected with hepatitis B virus with genotype B and those with genotype C in the Okinawa Islands: a prospective study

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12 December 2020

Hepatitis B virus of genotype B with or without recombination with genotype C over the precore region plus the core gene

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12 December 2020

Alteration of gene expression in human hepatocellular carcinoma with integrated hepatitis B virus DNA.

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12 December 2020

Long-term clinical remission induced by corticosteroid withdrawal therapy (CSWT) in patients with chronic hepatitis B infection: a prospective randomized controlled trial--CSWT with and without follow-up interferon-alpha therapy

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12 December 2020

Exploring the biological basis of hepatitis B e antigen in hepatitis B virus infection

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12 December 2020

Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx.

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12 December 2020

A novel steroid thyroid hormone receptor-related gene inappropriately expressed in human hepatocellular carcinoma

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12 December 2020

Hepatitis B virus DNA in liver, serum, and peripheral blood mononuclear cells after the clearance of serum hepatitis B virus surface antigen

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12 December 2020

Classifying hepatitis B virus genotypes

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12 December 2020

Integrations of the hepatitis B virus (HBV) and human papillomavirus (HPV) into the human telomerase reverse transcriptase (hTERT) gene in liver and cervical cancers

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12 December 2020

Hepatitis B virus and hepatocellular carcinoma

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12 December 2020

Large scaled analysis of hepatitis B virus (HBV) DNA integration in HBV related hepatocellular carcinomas

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12 December 2020

Hepatitis B virus X protein is essential for the activation of Wnt/beta-catenin signaling in hepatoma cells.

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12 December 2020

Preponderance of hepatitis B virus genotype B contributes to a better prognosis of chronic HBV infection in Okinawa, Japan

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12 December 2020

A viral kinetic study using pegylated interferon alfa-2b and/or lamivudine in patients with chronic hepatitis B/HBeAg negative

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12 December 2020

Long-term efficacy of interferon alpha-2b and lamivudine in combination compared to lamivudine monotherapy in patients with chronic hepatitis B. An Italian multicenter, randomized trial

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12 December 2020

Histological outcome during long-term lamivudine therapy.

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12 December 2020

Four years of lamivudine treatment in Chinese patients with chronic hepatitis B.

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12 December 2020

Association of a precore genomic variant of hepatitis B virus with fulminant hepatitis

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12 December 2020

Hepatitis B virus precore mutation and fulminant hepatitis in the United States. A polymerase chain reaction-based assay for the detection of specific mutation

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12 December 2020

Long-term follow-up of alpha-interferon treatment of patients with chronic hepatitis B.

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12 December 2020

Clinical characteristics of patients infected with hepatitis B virus genotypes A, B, and C.

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12 December 2020

Extended lamivudine treatment in patients with HBeAg-negative chronic hepatitis B.

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12 December 2020

Beneficial effect of prednisolone withdrawal followed by human lymphoblastoid interferon on the treatment of chronic type B hepatitis in Asians: a randomized controlled trial

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12 December 2020

Hepatitis B virus mutants with precore-region defects in two babies with fulminant hepatitis and their mothers positive for antibody to hepatitis B e antigen

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12 December 2020

Clearance of the original hepatitis B virus YMDD-motif mutants with emergence of distinct lamivudine-resistant mutants during prolonged lamivudine therapy

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12 December 2020

Basal core promoter mutations of hepatitis B virus increase the risk of hepatocellular carcinoma in hepatitis B carriers.

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12 December 2020

Long-term follow-up of HBeAg-positive patients treated with interferon alfa for chronic hepatitis B

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12 December 2020

Complete genomes, phylogenetic relatedness, and structural proteins of six strains of the hepatitis B virus, four of which represent two new genotypes

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12 December 2020

Peginterferon Alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B.

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12 December 2020

A novel PCR technique using Alu-specific primers to identify unknown flanking sequences from the human genome

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12 December 2020

Emergence and takeover of YMDD motif mutant hepatitis B virus during long-term lamivudine therapy and re-takeover by wild type after cessation of therapy

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12 December 2020

Differentiation of hepatitis B virus genotypes D and E by ELISA using monoclonal antibodies to epitopes on the preS2-region product

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12 December 2020

Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy.

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12 December 2020

Profile, spectrum and significance of HBV genotypes in chronic liver disease patients in the Indian subcontinent

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12 December 2020

Pediatric fulminant hepatic failure in endemic areas of hepatitis B infection: 15 years after universal hepatitis B vaccination

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12 December 2020

Hepatitis B virus-related insertional mutagenesis occurs frequently in human liver cancers and recurrently targets human telomerase gene.

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12 December 2020

Hepatitis B virus genotypes and virologic response in 694 patients in phase III studies of adefovir dipivoxil1.

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12 December 2020

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

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12 December 2020

Comparison of long-term effects of lymphoblastoid interferon alpha and recombinant interferon alpha-2a therapy in patients with chronic hepatitis B.

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12 December 2020

The long-term outcome of interferon-alpha treated and untreated patients with HBeAg-negative chronic hepatitis B

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12 December 2020

A dose-ranging study of the efficacy and tolerability of entecavir in Lamivudine-refractory chronic hepatitis B patients

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12 December 2020

A preliminary trial of lamivudine for chronic hepatitis B infection

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12 December 2020

Biologic properties of hepatitis B viral genomes with mutations in the precore promoter and precore open reading frame

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12 December 2020

Hepatitis B virus genotype B is associated with earlier HBeAg seroconversion compared with hepatitis B virus genotype C.

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12 December 2020

Vaccine-induced escape mutant of hepatitis B virus

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12 December 2020

Interferon decreases hepatocellular carcinogenesis in patients with cirrhosis caused by the hepatitis B virus: a pilot study

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12 December 2020

Interferon alpha treatment and retreatment of hepatitis B e antigen-negative chronic hepatitis B.

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12 December 2020

Clonal dominance of hematopoietic stem cells triggered by retroviral gene marking.

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12 December 2020

Long-term safety of lamivudine treatment in patients with chronic hepatitis B.

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12 December 2020

Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised trial

1 reference

12 December 2020

Hepatitis B defective virus with rearrangements in the preS gene during chronic HBV infection

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12 December 2020

The small envelope protein is required for secretion of a naturally occurring hepatitis B virus mutant with pre-S1 deleted.

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12 December 2020

Changes of hepatitis B virus DNA in liver and serum caused by recombinant leukocyte interferon treatment: analysis of intrahepatic replicative hepatitis B virus DNA.

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12 December 2020

Effects of extended lamivudine therapy in Asian patients with chronic hepatitis B. Asia Hepatitis Lamivudine Study Group

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12 December 2020

The enigmatic X gene of hepatitis B virus

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12 December 2020

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12 December 2020

Pegylated interferon-alpha2b: pharmacokinetics, pharmacodynamics, safety, and preliminary efficacy data. Hepatitis C Intervention Therapy Group

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12 December 2020

Serological detection of hepatitis B virus genotypes by ELISA with monoclonal antibodies to type-specific epitopes in the preS2-region product

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12 December 2020

Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis B.

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12 December 2020

Chromosomal sites for hepatitis B virus integration in human hepatocellular carcinoma

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12 December 2020

Hepatocellular carcinoma and hepatitis B virus. A prospective study of 22 707 men in Taiwan

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12 December 2020

Efficacy of lamivudine in patients with hepatitis B e antigen-negative/hepatitis B virus DNA-positive (precore mutant) chronic hepatitis B. Lamivudine Precore Mutant Study Group

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12 December 2020

Does hepatitis B virus (HBV) genotype influence the clinical outcome of HBV infection?

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12 December 2020

Functional analysis of hepatitis B virus reactivating in hepatitis B surface antigen-negative individuals

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12 December 2020

The influence of hepatitis B virus genotype on the development of lamivudine resistance during long-term treatment.

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12 December 2020

Sequential treatment with lamivudine and interferon monotherapies in patients with chronic hepatitis B not responding to interferon alone: results of a pilot study

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12 December 2020

Interferon-lamivudine combination is no better than lamivudine alone in anti-HBe-positive chronic hepatitis B.

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12 December 2020

Mutations in the precore region of hepatitis B virus DNA in patients with fulminant and severe hepatitis

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12 December 2020

Mutation preventing formation of hepatitis B e antigen in patients with chronic hepatitis B infection.

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12 December 2020

Properties of hepatitis B virus pre-S1 deletion mutants

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12 December 2020

10.1007/S00535-006-1774-5

Identifiers

DOI

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14 August 2017

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PubMed ID

16568369