(Q36434294)

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Conserved Role of an N-Linked Glycan on the Surface Antigen of Human Immunodeficiency Virus Type 1 Modulating Virus Sensitivity to Broadly Neutralizing Antibodies against the Receptor and Coreceptor Binding Sites

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26512079%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Conserved Role of an N-Linked Glycan on the Surface Antigen of Human Immunodeficiency Virus Type 1 Modulating Virus Sensitivity to Broadly Neutralizing Antibodies against the Receptor and Coreceptor Binding Sites (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26512079%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

5

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28 February 2020

author name string

Samantha Townsley

1

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28 February 2020

Yun Li

2

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28 February 2020

Yury Kozyrev

3

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28 February 2020

Brad Cleveland

4

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28 February 2020

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28 October 2015

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28 February 2020

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13

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Journal of Virology

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28 February 2020

90

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28 February 2020

2

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28 February 2020

829-841

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28 February 2020

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface

1 reference

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30 September 2017

Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers

1 reference

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30 September 2017

Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

1 reference

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30 September 2017

Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

1 reference

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30 September 2017

Epitope mapping of conformational V2-specific anti-HIV human monoclonal antibodies reveals an immunodominant site in V2.

1 reference

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Purification of recombinant vaccinia virus-expressed monomeric HIV-1 gp120 to apparent homogeneity

1 reference

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30 September 2017

Sequences in glycoprotein gp41, the CD4 binding site, and the V2 domain regulate sensitivity and resistance of HIV-1 to broadly neutralizing antibodies

1 reference

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Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses

1 reference

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30 September 2017

The design and evaluation of HIV-1 vaccines

1 reference

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Envelope deglycosylation enhances antigenicity of HIV-1 gp41 epitopes for both broad neutralizing antibodies and their unmutated ancestor antibodies

1 reference

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30 September 2017

Broad neutralization coverage of HIV by multiple highly potent antibodies

1 reference

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30 September 2017

Characteristics of the earliest cross-neutralizing antibody response to HIV-1.

1 reference

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30 September 2017

Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

1 reference

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Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

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30 September 2017

The role of antibodies in HIV vaccines

1 reference

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Temporal analysis of HIV envelope sequence evolution and antibody escape in a subtype A-infected individual with a broad neutralizing antibody response

1 reference

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Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

1 reference

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Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies

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Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-L

1 reference

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Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

1 reference

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30 September 2017

The V1-V3 region of a brain-derived HIV-1 envelope glycoprotein determines macrophage tropism, low CD4 dependence, increased fusogenicity and altered sensitivity to entry inhibitors

1 reference

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A single site for N-linked glycosylation in the envelope glycoprotein of feline immunodeficiency virus modulates the virus-receptor interaction

1 reference

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Evaluating neutralizing antibodies against HIV, SIV, and SHIV in luciferase reporter gene assays

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Removal of a single N-linked glycan in human immunodeficiency virus type 1 gp120 results in an enhanced ability to induce neutralizing antibody responses

1 reference

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Influences of glycosylation on antigenicity, immunogenicity, and protective efficacy of ebola virus GP DNA vaccines

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Human immunodeficiency virus type 1 V1-V2 envelope loop sequences expand and add glycosylation sites over the course of infection, and these modifications affect antibody neutralization sensitivity

1 reference

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Viral evolution in macaques coinfected with CCR5- and CXCR4-tropic SHIVs in the presence or absence of vaccine-elicited anti-CCR5 SHIV neutralizing antibodies.

1 reference

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Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infection

1 reference

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Identification of two N-linked glycosylation sites within the core of the simian immunodeficiency virus glycoprotein whose removal enhances sensitivity to soluble CD4.

1 reference

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Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies

1 reference

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Identification of a new quaternary neutralizing epitope on human immunodeficiency virus type 1 virus particles

1 reference

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Modified HIV envelope proteins with enhanced binding to neutralizing monoclonal antibodies

1 reference

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Infectious molecular clone of a recently transmitted pediatric human immunodeficiency virus clade C isolate from Africa: evidence of intraclade recombination

1 reference

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Intrinsic obstacles to human immunodeficiency virus type 1 coreceptor switching

1 reference

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1 reference

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1 reference

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Passive immunotherapy in simian immunodeficiency virus-infected macaques accelerates the development of neutralizing antibodies

1 reference

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N-linked glycosylation of the V3 loop and the immunologically silent face of gp120 protects human immunodeficiency virus type 1 SF162 from neutralization by anti-gp120 and anti-gp41 antibodies

1 reference

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Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1

1 reference

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Antibody protection: passive immunization of neonates against oral AIDS virus challenge.

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Antibody neutralization and escape by HIV-1

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Role of N-linked glycans in a human immunodeficiency virus envelope glycoprotein: effects on protein function and the neutralizing antibody response

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A potent cross-clade neutralizing human monoclonal antibody against a novel epitope on gp41 of human immunodeficiency virus type 1.

1 reference

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N-linked glycosylation in the V3 region of HIV type 1 surface antigen modulates coreceptor usage in viral infection

1 reference

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Loss of a single N-linked glycan allows CD4-independent human immunodeficiency virus type 1 infection by altering the position of the gp120 V1/V2 variable loops

1 reference

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Energetics of the HIV gp120-CD4 binding reaction

1 reference

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Adaptation of a CCR5-using, primary human immunodeficiency virus type 1 isolate for CD4-independent replication

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Mapping of epitopes exposed on intact human immunodeficiency virus type 1 (HIV-1) virions: a new strategy for studying the immunologic relatedness of HIV-1.

1 reference

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The antigenic structure of the HIV gp120 envelope glycoprotein

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Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

1 reference

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CD4-Induced conformational changes in the human immunodeficiency virus type 1 gp120 glycoprotein: consequences for virus entry and neutralization

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Human monoclonal antibodies to the V3 loop of HIV-1 with intra- and interclade cross-reactivity.

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Atomic structure of the ectodomain from HIV-1 gp41

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CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.

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Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding

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Specificity of antibodies produced against native or desialylated human immunodeficiency virus type 1 recombinant gp160.

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1 reference

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1 reference

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Complete nucleotide sequence of the AIDS virus, HTLV-III

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Oligomeric organization of gp120 on infectious human immunodeficiency virus type 1 particles

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Envelope proteins from clinical isolates of human immunodeficiency virus type 1 that are refractory to neutralization by soluble CD4 possess high affinity for the CD4 receptor

1 reference

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Envelope glycoproteins from biologically diverse isolates of immunodeficiency viruses have widely different affinities for CD4

1 reference

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A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals

1 reference

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30 September 2017

Alterations in potential sites for glycosylation predominate during evolution of the simian immunodeficiency virus envelope gene in macaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702696

30 September 2017

Neutralization of diverse human immunodeficiency virus type 1 variants by an anti-V3 human monoclonal antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702696

30 September 2017

Recombinant human Fab fragments neutralize human type 1 immunodeficiency virus in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702696

30 September 2017

Determining kinetics and affinities of protein interactions using a parallel real-time label-free biosensor, the Octet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702696

28 June 2018

A role for carbohydrates in immune evasion in AIDS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702696

28 June 2018

Generation of Human Monoclonal Antibodies against HIV-1 Proteins; Electrofusion and Epstein-Barr Virus Transformation for Peripheral Blood Lymphocyte Immortalization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702696

28 June 2018

Escherichia coli expression, purification, and biological activity of a truncated soluble CD4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702696

28 June 2018

Posttranslational modifications within the HIV-1 envelope glycoprotein which restrict virus assembly and CD4-dependent infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702696

28 June 2018

Passive immunization with human neutralizing monoclonal antibodies against HIV-1 in macaque models: experimental approaches.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702696

21 September 2018

CCR5 use by human immunodeficiency virus type 1 is associated closely with the gp120 V3 loop N-linked glycosylation site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702696

21 September 2018

HIV-1 tropism for the central nervous system: Brain-derived envelope glycoproteins with lower CD4 dependence and reduced sensitivity to a fusion inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702696

21 September 2018

HIV-1 acute infection env glycomutants designed from 3D model: effects on processing, antigenicity, and neutralization sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702696

21 September 2018

Envelope-constrained neutralization-sensitive HIV-1 after heterosexual transmission

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702696

21 September 2018

Enhanced immunogenicity of a human immunodeficiency virus type 1 env DNA vaccine by manipulating N-glycosylation signals. Effects of elimination of the V3 N306 glycan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702696

21 September 2018

gp120: Biologic aspects of structural features

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702696

21 September 2018

HLA-DR-positive dendritic cells of the normal human choroid plexus: a potential reservoir of HIV in the central nervous system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702696

21 September 2018

An N-glycan within the human immunodeficiency virus type 1 gp120 V3 loop affects virus neutralization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702696

21 September 2018

Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702696

21 September 2018

Human immunodeficiency virus type 2 envelope glycoprotein: differential CD4 interactions of soluble gp120 versus the assembled envelope complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702696

21 September 2018

Highly conserved HIV-1 gp120 glycans proximal to CD4-binding region affect viral infectivity and neutralizing antibody induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/26512079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repertoire of neutralizing human monoclonal antibodies specific for the V3 domain of HIV-1 gp120

1 reference

https://pubmed.ncbi.nlm.nih.gov/26512079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevalence of a V2 epitope in clade B primary isolates and its recognition by sera from HIV-1-infected individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/26512079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.02321-15

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26512079%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

release_tjepee2jcvbvdftgt7avwi2bjy

1 reference

https://api.fatcat.wiki/v0/release/tjepee2jcvbvdftgt7avwi2bjy

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26512079%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26512079%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

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