(Q36446536)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22845314%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Regulation of apoptosis in HL-1 cardiomyocytes by phosphorylation of the receptor tyrosine kinase EphA2 and protection by lithocholic acid (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22845314%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

0 references

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22845314%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

J Jehle

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22845314%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

I Staudacher

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22845314%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Pa Schweizer

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22845314%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

R Becker

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22845314%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Ha Katus

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22845314%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

D Thomas

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22845314%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

language of work or name

English

0 references

publication date

1 December 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22845314%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Pharmacology

9 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22845314%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

volume

167

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22845314%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22845314%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

page(s)

1563-1572

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22845314%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

9 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3514767/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

EphrinA1-EphA2 interaction-mediated apoptosis and FMS-like tyrosine kinase 3 receptor ligand-induced immunotherapy inhibit tumor growth in a breast cancer mouse model

1 reference

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Guide to Receptors and Channels (GRAC), 5th edition

30 September 2017

1 reference

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Silencing receptor EphA2 induces apoptosis and attenuates tumor growth in malignant mesothelioma.

30 September 2017

1 reference

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Novel roles for hERG K(+) channels in cell proliferation and apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

Lithocholic acid is an Eph-ephrin ligand interfering with Eph-kinase activation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

The aging heart and post-infarction left ventricular remodeling.

30 September 2017

1 reference

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Emerging strategies for EphA2 receptor targeting for cancer therapeutics

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

Apoptosis induction by doxazosin and other quinazoline alpha1-adrenoceptor antagonists: a new mechanism for cancer treatment?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

Dual targeting of EphA2 and FAK in ovarian carcinoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

The EphA2 receptor and ephrinA1 ligand in solid tumors: function and therapeutic targeting

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

Identification and functional analysis of phosphorylated tyrosine residues within EphA2 receptor tyrosine kinase.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

Doxazosin induces apoptosis of cells expressing hERG K+ channels.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

Noonan syndrome and related disorders: dysregulated RAS-mitogen activated protein kinase signal transduction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

Role of protein-tyrosine phosphatase SHP2 in focal adhesion kinase down-regulation during neutrophil cathepsin G-induced cardiomyocytes anoikis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

Doxazosin induces activation of GADD153 and cleavage of focal adhesion kinase in cardiomyocytes en route to apoptosis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

Immunocompetent mouse model of breast cancer for preclinical testing of EphA2-targeted therapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

Decreased tumorigenic potential of EphA2-overexpressing breast cancer cells following treatment with adenoviral vectors that express EphrinA1.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

Ligation of EphA2 by Ephrin A1-Fc inhibits pancreatic adenocarcinoma cellular invasiveness

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

Overexpression and functional alterations of the EphA2 tyrosine kinase in cancer

30 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

30 September 2017

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Doxazosin and terazosin suppress prostate growth by inducing apoptosis: clinical significance

21 January 2018

1 reference

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Doxazosin induces apoptosis in cardiomyocytes cultured in vitro by a mechanism that is independent of alpha1-adrenergic blockade.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

Apoptosis and heart failure: A critical review of the literature

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

The effect of lithocholic acid on proliferation and apoptosis during the early stages of colon carcinogenesis: differential effect on apoptosis in the presence of a colon carcinogen

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

The ephrin A1-EphA2 system promotes cardiac stem cell migration after infarction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

Myocardial cell death in fibrillating and dilated human right atria.

28 June 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02117.X

Connexin 43 gene therapy prevents persistent atrial fibrillation in a porcine model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02117.X

Evolution of the atrial fibrillation substrate in experimental congestive heart failure: angiotensin-dependent and -independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02117.X

Receptor tyrosine kinase EphA2 is regulated by p53-family proteins and induces apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02117.X

EphA2: a determinant of malignant cellular behavior and a potential therapeutic target in pancreatic adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02117.X

Silencing the receptor EphA2 suppresses the growth and haptotaxis of malignant mesothelioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02117.X

Genetic suppression of atrial fibrillation using a dominant-negative ether-a-go-go-related gene mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02117.X

hERG K+ channel-associated cardiac effects of the antidepressant drug desipramine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02117.X

Atrial natriuretic peptide induces apoptosis in neonatal rat cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02117.X

RNA interference targeting EphA2 inhibits proliferation, induces apoptosis, and cooperates with cytotoxic drugs in human glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02117.X

Suppression of persistent atrial fibrillation by genetic knockdown of caspase 3: a pre-clinical pilot study

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

Antibody targeting of the EphA2 tyrosine kinase inhibits malignant cell behavior

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514767

Major cardiovascular events in hypertensive patients randomized to doxazosin vs chlorthalidone: the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT). ALLHAT Collaborative Research Group

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22845314

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Intramyocardial administration of chimeric ephrinA1-Fc promotes tissue salvage following myocardial infarction in mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22845314

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1476-5381.2012.02117.X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22845314%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22845314%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

22845314

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22845314%20AND%20SRC:MED&resulttype=core&format=json