(Q36446865)

English

Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responses

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scholarly article

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Europe PubMed Central

PMC publication ID

14 August 2017

Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responses (English)

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Europe PubMed Central

PMC publication ID

14 August 2017

toll-like receptor

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1 reference

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inferred from title

Rachel R. Caspi

object named as

Rachel R Caspi

6

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author name string

De Yang

1

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Europe PubMed Central

PMC publication ID

14 August 2017

Qian Chen

2

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Europe PubMed Central

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14 August 2017

Shao Bo Su

3

1 reference

Europe PubMed Central

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14 August 2017

Ping Zhang

4

1 reference

Europe PubMed Central

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14 August 2017

Kahori Kurosaka

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Suzanne M Michalek

7

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Helene F Rosenberg

8

1 reference

Europe PubMed Central

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14 August 2017

Ning Zhang

9

1 reference

Europe PubMed Central

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14 August 2017

Joost J Oppenheim

10

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14 August 2017

language of work or name

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publication date

14 January 2008

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Europe PubMed Central

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14 August 2017

Journal of Experimental Medicine

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Europe PubMed Central

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14 August 2017

205

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Europe PubMed Central

PMC publication ID

14 August 2017

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

79-90

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Schistosoma mansoni infection in eosinophil lineage-ablated mice

1 reference

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Expanding the effector CD4 T-cell repertoire: the Th17 lineage.

1 reference

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30 September 2017

Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance.

1 reference

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30 September 2017

Pathogen recognition and innate immunity

1 reference

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30 September 2017

High mobility group box 1 protein interacts with multiple Toll-like receptors

1 reference

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Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus

1 reference

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30 September 2017

Heat shock proteins as endogenous adjuvants in sterile and septic inflammation

1 reference

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30 September 2017

Alarmins: chemotactic activators of immune responses

1 reference

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30 September 2017

Mouse cathelin-related antimicrobial peptide chemoattracts leukocytes using formyl peptide receptor-like 1/mouse formyl peptide receptor-like 2 as the receptor and acts as an immune adjuvant.

1 reference

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30 September 2017

Human ribonuclease A superfamily members, eosinophil-derived neurotoxin and pancreatic ribonuclease, induce dendritic cell maturation and activation

1 reference

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30 September 2017

Toll-like receptor control of the adaptive immune responses

1 reference

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30 September 2017

HMGB1 is an endogenous immune adjuvant released by necrotic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Toll-like receptor signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Relationship between structures and biological activities of mycoplasmal diacylated lipopeptides and their recognition by toll-like receptors 2 and 6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Cell surface expression of an endoplasmic reticulum resident heat shock protein gp96 triggers MyD88-dependent systemic autoimmune diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Defensins: antimicrobial peptides of innate immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Eosinophil-derived neurotoxin (EDN), an antimicrobial protein with chemotactic activities for dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Heat shock proteins as ligands of toll-like receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

The immunobiology of schistosomiasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Antimicrobial peptides of multicellular organisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Eosinophils, eosinophil ribonucleases, and their role in host defense against respiratory virus pathogens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Discrimination of bacterial lipoproteins by Toll-like receptor 6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Dendritic-cell function in Toll-like receptor- and MyD88-knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

A critical role for p38 mitogen-activated protein kinase in the maturation of human blood-derived dendritic cells induced by lipopolysaccharide, TNF-alpha, and contact sensitizers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

The extra domain A of fibronectin activates Toll-like receptor 4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Eosinophil granule proteins and their role in disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

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Synthesis of polyacrylamides N-substituted with PNA-like oligonucleotide mimics for molecular diagnostic applications

1 reference

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30 September 2017

Cutting edge: immature dendritic cells generated from monocytes in the presence of TGF-beta 1 express functional C-C chemokine receptor 6

1 reference

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30 September 2017

The role of chemokines in the regulation of dendritic cell trafficking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Localization of eosinophil-derived neurotoxin and eosinophil cationic protein in neutrophilic leukocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Dendritic cells and the control of immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Purification of human eosinophil-derived neurotoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

Toll-like receptor 2 ligands inhibit TH2 responses to mite allergen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

21 September 2018

TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

21 September 2018

Essential role of the MyD88 pathway, but nonessential roles of TLRs 2, 4, and 9, in the adjuvant effect promoting Th1-mediated autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

21 September 2018

TLR2 agonist ameliorates established allergic airway inflammation by promoting Th1 response and not via regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

21 September 2018

TLR ligands can activate dendritic cells to provide a MyD88-dependent negative signal for Th2 cell development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

21 September 2018

The Toll-like receptor-2/6 agonist macrophage-activating lipopeptide-2 cooperates with IFN-gamma to reverse the Th2 skew in an in vitro allergy model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

21 September 2018

The role of the p38 mitogen-activated protein kinase, extracellular signal-regulated kinase, and phosphoinositide-3-OH kinase signal transduction pathways in CD40 ligand-induced dendritic cell activation and expansion of virus-specific CD8+ T cell m

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

21 September 2018

A Toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

21 September 2018

Multiple roles of antimicrobial defensins, cathelicidins, and eosinophil-derived neurotoxin in host defense

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

21 September 2018

Airway peptidoglycan and immunostimulatory DNA exposures have divergent effects on the development of airway allergen hypersensitivities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

21 September 2018

Cutting edge: activation of Toll-like receptor 2 induces a Th2 immune response and promotes experimental asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

21 September 2018

Hyaluronan fragments stimulate endothelial recognition of injury through TLR4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

21 September 2018

Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

21 September 2018

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1 reference

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21 September 2018

IL-4-dependent regulation of TGF-alpha and TGF-beta1 expression in human eosinophils.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

21 September 2018

Recombinant human eosinophil-derived neurotoxin/RNase 2 functions as an effective antiviral agent against respiratory syncytial virus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

21 September 2018

Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20062027

21 January 2018

CD8- dendritic cell activation status plays an integral role in influencing Th2 response development

1 reference

https://pubmed.ncbi.nlm.nih.gov/18195069

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18195069

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The PI3 kinase, p38 SAP kinase, and NF-kappaB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte-derived dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18195069

12 December 2020

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inferred from PubMed ID database lookup

Differential regulation of responsiveness to fMLP and C5a upon dendritic cell maturation: correlation with receptor expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18195069

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antimicrobial proteins act as "alarmins" in joint immune defense

1 reference

https://pubmed.ncbi.nlm.nih.gov/18195069

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parasite-induced Th2 polarization is associated with down-regulated dendritic cell responsiveness to Th1 stimuli and a transient delay in T lymphocyte cycling

1 reference

https://pubmed.ncbi.nlm.nih.gov/18195069

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Major basic protein and eosinophil-derived neurotoxin concentrations in nasal-lavage fluid after antigen challenge: effect of systemic corticosteroids and relationship to eosinophil influx

1 reference

https://pubmed.ncbi.nlm.nih.gov/18195069

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum eosinophil cationic protein (ECP) and eosinophil protein X (EPX) in childhood asthma: the influence of atopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18195069

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of eosinophil granule proteins in various body fluids: is there a relation to clinical variables in childhood asthma?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18195069

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.20062027

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

ResearchGate publication ID

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