(Q36453107)

English

Synthesis and biological characterization of (3R,4R)-4-(2-(benzhydryloxy)ethyl)-1-((R)-2-hydroxy-2-phenylethyl)-piperidin-3-ol and its stereoisomers for activity toward monoamine transporters

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Europe PubMed Central

PMC publication ID

14 August 2017

Synthesis and biological characterization of (3R,4R)-4-(2-(benzhydryloxy)ethyl)-1-((R)-2-hydroxy-2-phenylethyl)-piperidin-3-ol and its stereoisomers for activity toward monoamine transporters (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Prashant S Kharkar

object named as

Prashant S Kharkar

1

0 references

object named as

Juan Zhen

3

0 references

object named as

Aloke K Dutta

6

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author name string

Angela M Batman

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Patrick M Beardsley

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Maarten E A Reith

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

publication date

1 July 2009

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

7

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

1075-1085

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

D-161, a novel pyran-based triple monoamine transporter blocker: behavioral pharmacological evidence for antidepressant-like action

1 reference

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30 September 2017

Cocaine reward and locomotion stimulation in mice with reduced dopamine transporter expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517155

30 September 2017

Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517155

30 September 2017

Development of a rationally designed, low abuse potential, biogenic amine releaser that suppresses cocaine self-administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517155

30 September 2017

Interaction between a hydroxypiperidine analogue of 4-(2-benzhydryloxy-ethyl)-1-(4-fluorobenzyl)piperidine and Aspartate 68 in the human dopamine transporter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517155

30 September 2017

Dopamine transporter as target for drug development of cocaine dependence medications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517155

30 September 2017

Chemistry, design, and structure-activity relationship of cocaine antagonists

1 reference

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30 September 2017

Self-administration of cocaine and the cocaine analog RTI-113: relationship to dopamine transporter occupancy determined by PET neuroimaging in rhesus monkeys

1 reference

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30 September 2017

Synthesis and preliminary characterization of a high-affinity novel radioligand for the dopamine transporter

1 reference

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30 September 2017

Oxygenated analogues of 1-[2-(Diphenylmethoxy)ethyl]- and 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909) as potential extended-action cocaine-abuse therapeutic agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517155

30 September 2017

Pharmacotherapies for treatment of cocaine abuse: preclinical aspects

1 reference

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30 September 2017

Tolerance in the replacement of the benzhydrylic O atom in 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives by an N atom: development of new-generation potent and selective N-analogue molecules for the dopamine transporter

1 reference

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30 September 2017

Asymmetric catalysis with water: efficient kinetic resolution of terminal epoxides by means of catalytic hydrolysis

1 reference

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30 September 2017

Highly selective, novel analogs of 4-[2-(diphenylmethoxy)ethyl]- 1-benzylpiperidine for the dopamine transporter: effect of different aromatic substitutions on their affinity and selectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517155

30 September 2017

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517155

30 September 2017

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517155

30 September 2017

Cocaine receptors on dopamine transporters are related to self-administration of cocaine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517155

30 September 2017

Cocaine inhibition of ligand binding at dopamine, norepinephrine and serotonin transporters: a structure-activity study

1 reference

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30 September 2017

Opium, cocaine and marijuana in American history.

1 reference

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30 September 2017

Relationship between subjective effects of cocaine and dopamine transporter occupancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517155

28 June 2018

Structure-activity relationship studies of novel 4-[2-[bis(4-fluorophenyl)methoxy]ethyl]-1-(3-phenylpropyl)piperidine analogs: synthesis and biological evaluation at the dopamine and serotonin transporter sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517155

28 June 2018

Effects of three monoamine uptake inhibitors on behavior maintained by cocaine or food presentation in rhesus monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517155

28 June 2018

Effects of cocaine and related drugs in nonhuman primates. III. Self-administration by squirrel monkeys

1 reference

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28 June 2018

Behavioral effects of selective dopaminergic compounds in rats discriminating cocaine injections

1 reference

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28 June 2018

Chronic food restriction and dopamine transporter function in rat striatum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517155

21 September 2018

High affinity hydroxypiperidine analogues of 4-(2-benzhydryloxyethyl)-1-(4-fluorobenzyl)piperidine for the dopamine transporter: stereospecific interactions in vitro and in vivo.

1 reference

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21 September 2018

Development of long-acting dopamine transporter ligands as potential cocaine-abuse therapeutic agents: chiral hydroxyl-containing derivatives of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(diphenylmethoxy)ethyl]-4-

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517155

21 September 2018

Structure-activity relationship studies of 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives and their N-analogues: evaluation of O-and N-analogues and their binding to monoamine transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517155

21 September 2018

Identifiers

10.1002/CMDC.200900085

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Europe PubMed Central

PMC publication ID

14 August 2017

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Europe PubMed Central

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14 August 2017

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Europe PubMed Central

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14 August 2017

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