(Q36453377)

14 August 2017

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title

Phospho-proteomic immune analysis by flow cytometry: from mechanism to translational medicine at the single-cell level (English)

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14 August 2017

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translational medicine

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2

Garry P Nolan

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14 August 2017

Omar D Perez

1

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14 August 2017

publication date

1 April 2006

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14 August 2017

published in

Immunological Reviews

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14 August 2017

volume

210

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14 August 2017

page(s)

208-228

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describes a project that uses

14 August 2017

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Cytomics--new technologies: towards a human cytome project

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Cytomics: an entry to biomedical cell systems biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Interaction network containing conserved and essential protein complexes in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Composition and function of g protein-coupled receptor signalsomes controlling mitogen-activated protein kinase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Signaling mechanisms for regulation of chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Variations on a theme: the many modes of cytokinesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Chemokines in innate and adaptive host defense: basic chemokinese grammar for immune cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Gene microarray identification of redox and mitochondrial elements that control resistance or sensitivity to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

MAP kinase-mediated phosphorylation of distinct pools of histone H3 at S10 or S28 via mitogen- and stress-activated kinase 1/2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Constitutively active cytoplasmic c-Jun N-terminal kinase 1 is a dominant regulator of dendritic architecture: role of microtubule-associated protein 2 as an effector

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Subcellular localization determines the protective effects of activated ERK2 against distinct apoptogenic stimuli in myeloid leukemia cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Cell cycle-dependent nucleocytoplasmic shuttling of the neurofibromatosis 2 tumour suppressor merlin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Dual role for TGF-beta1 in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

11-color, 13-parameter flow cytometry: identification of human naive T cells by phenotype, function, and T-cell receptor diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Ontogeny of gamma delta T cells in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Heterogeneous calcium flux in peripheral T cell subsets revealed by five-color flow cytometry using log-ratio circuitry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

8 color, 10-parameter flow cytometry to elucidate complex leukocyte heterogeneity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Fluorescence Activated Cell Sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Two-color immunofluorescence using a fluorescence-activated cell sorter

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Three-color immunofluorescence analysis of mouse B-lymphocyte subpopulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Fluorescent phycobiliprotein conjugates for analyses of cells and molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

High-speed cell sorting: fundamentals and recent advances

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Flow cytometric analysis of vaccine responses: how many colors are enough?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Beyond six colors: a new era in flow cytometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Protein tyrosine phosphatases and the immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

The protein kinase complement of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

The mouse kinome: discovery and comparative genomics of all mouse protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Kinomics: methods for deciphering the kinome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Oncogenic kinase signaling in human neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

CD45: a critical regulator of signaling thresholds in immune cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Analysis of protein phosphorylation and cellular signaling events by flow cytometry: techniques and clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Intracellular phospho-protein staining techniques for flow cytometry: monitoring single cell signaling events

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Immunofluorescent quantification of tyrosine phosphorylation of cellular proteins in whole cells by flow cytometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Flow cytometric analysis of protein-tyrosine phosphorylation in peripheral T cell subsets. Application to healthy and HIV-seropositive subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Detection of intracellular phosphorylated STAT-4 by flow cytometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Measurement of MAP kinase activation by flow cytometry using phospho-specific antibodies to MEK and ERK: potential for pharmacodynamic monitoring of signal transduction inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Single-cell analysis of signal transduction in CD4 T cells stimulated by antigen in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Flow cytometric detection of total and serine 473 phosphorylated Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Detection of serine 473 phosphorylated Akt in acute myeloid leukaemia blasts by flow cytometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Immunoreactivity of Stat5 phosphorylated on tyrosine as a cell-based measure of Bcr/Abl kinase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Molecular and functional profiling of memory CD8 T cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Magnetic relaxation switches capable of sensing molecular interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Activation of the PKB/AKT pathway by ICAM-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Leukocyte functional antigen 1 lowers T cell activation thresholds and signaling through cytohesin-1 and Jun-activating binding protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

LFA-1 signaling through p44/42 is coupled to perforin degranulation in CD56+CD8+ natural killer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Distinct mechanisms of STAT phosphorylation via the interferon-alpha/beta receptor. Selective inhibition of STAT3 and STAT5 by piceatannol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Cytokines: shared receptors, distinct functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

The role of Stat5a and Stat5b in signaling by IL-2 family cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Causal protein-signaling networks derived from multiparameter single-cell data

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Twenty-five years of clinical flow cytometry: AIDS accelerated global instrument distribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Single cell profiling of potentiated phospho-protein networks in cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Flow cytometric assessment of the signaling status of human B lymphocytes from normal and autoimmune individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

CHIR-258, a novel, multitargeted tyrosine kinase inhibitor for the potential treatment of t(4;14) multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Whole blood fixation and permeabilization protocol with red blood cell lysis for flow cytometry of intracellular phosphorylated epitopes in leukocyte subpopulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Systems biology in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Leroy Hood expounds the principles, practice and future of systems biology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Clinical proteomics: Written in blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Protein microarrays: catching the proteome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Clinical applications of proteomics: proteomic pattern diagnostics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Clinical proteomics: Applications for prostate cancer biomarker discovery and detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Protein microarray detection strategies: focus on direct detection technologies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Multiplexed sandwich assays in microarray format

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

An immunoproteomic approach for identification of clinical biomarkers for monitoring disease: application to cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

High-throughput methods for measuring autoantibodies in systemic lupus erythematosus and other autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Protein arrays for autoantibody profiling and fine‐specificity mapping

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Autoantigen microarrays for multiplex characterization of autoantibody responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Multiplexed particle-based flow cytometric assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Tissue microarrays: a practical guide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Array technology and proteomics in autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Protein arrays for studying blood cells and their secreted products

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Utility of reverse phase protein arrays: applications to signalling pathways and human body arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Protein microarrays: molecular profiling technologies for clinical specimens

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Protein microarrays for multiplex analysis of signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Use of reverse phase protein microarrays and reference standard development for molecular network analysis of metastatic ovarian carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Mapping molecular networks using proteomics: a vision for patient-tailored combination therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

An array of possibilities for the study of autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

twilight; a Bioconductor package for estimating the local false discovery rate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

A mixture model for estimating the local false discovery rate in DNA microarray analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Cytomics in predictive medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Systems biology: its practice and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

Genome informatics: current status and future prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

National Heart, Lung, And Blood Institute Clinical Proteomics Working Group report

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00364.X

10.1111/J.0105-2896.2006.00364.X

21 January 2018

Identifiers

DOI

1 reference

14 August 2017

1 reference