(Q36460440)

14 August 2017

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title

Microbicides and other topical strategies to prevent vaginal transmission of HIV. (English)

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14 August 2017

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Michael M Lederman

1

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14 August 2017

Robin E Offord

series ordinal

2

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14 August 2017

Oliver Hartley

series ordinal

3

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14 August 2017

publication date

1 May 2006

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Nature Reviews Immunology

14 August 2017

published in

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14 August 2017

volume

6

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14 August 2017

issue

5

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14 August 2017

page(s)

371-382

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The effect of number of exposures on the risk of heterosexual HIV transmission

14 August 2017

cites work

1 reference

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21 January 2018

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21 January 2018

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21 January 2018

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Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: HIVNET 012 randomised trial

21 January 2018

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Alpha-(1-3)- and alpha-(1-6)-D-mannose-specific plant lectins are markedly inhibitory to human immunodeficiency virus and cytomegalovirus infections in vitro

21 January 2018

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Host-directed and immune-based therapies for human immunodeficiency virus infection

21 January 2018

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Immunological characterization of human vaginal xenografts in immunocompromised mice: development of a small animal model for the study of human immunodeficiency virus-1 infection

21 January 2018

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Chemokines are present in the genital tract of HIV-seropositive and HIV-seronegative women: correlation with other immune mediators

21 January 2018

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HIV/AIDS in women: an expanding epidemic

21 January 2018

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AIDS research. Male circumcision thwarts HIV infection

31 March 2020

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Men's attitudes to condoms and female controlled means of protection against HIV and STDs in south-western Uganda.

31 March 2020

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Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: the ANRS 1265 Trial

31 March 2020

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Target cells in vaginal HIV transmission

31 March 2020

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HIV binding, penetration, and primary infection in human cervicovaginal tissue

31 March 2020

1 reference

The innate and early immune response to pathogen challenge in the female genital tract and the pivotal role of epithelial cells

31 March 2020

1 reference

Viricidal effect of Lactobacillus acidophilus on human immunodeficiency virus type 1: possible role in heterosexual transmission

31 March 2020

1 reference

Concern voiced over "dry sex" practices in South Africa

31 March 2020

1 reference

HIV-1 infection associated with abnormal vaginal flora morphology and bacterial vaginosis

31 March 2020

1 reference

Bacterial vaginosis and susceptibility to HIV infection in South African women: a nested case-control study

31 March 2020

1 reference

The role of sexually transmitted diseases in HIV transmission

31 March 2020

1 reference

Estrogen protects against vaginal transmission of simian immunodeficiency virus

31 March 2020

1 reference

Progesterone implants enhance SIV vaginal transmission and early virus load

31 March 2020

1 reference

Propagation and dissemination of infection after vaginal transmission of simian immunodeficiency virus

31 March 2020

1 reference

Simian immunodeficiency virus rapidly penetrates the cervicovaginal mucosa after intravaginal inoculation and infects intraepithelial dendritic cells

31 March 2020

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Amplified HIV transmission and new approaches to HIV prevention

31 March 2020

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Frequent detection of acute primary HIV infection in men in Malawi

31 March 2020

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Rates of HIV-1 transmission per coital act, by stage of HIV-1 infection, in Rakai, Uganda

31 March 2020

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The CCR5 and CXCR4 coreceptors--central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection

31 March 2020

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Expression and function of CCR5 and CXCR4 on human Langerhans cells and macrophages: implications for HIV primary infection

31 March 2020

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HIV coreceptor downregulation as antiviral principle: SDF-1alpha-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication

31 March 2020

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Human epithelial beta-defensins 2 and 3 inhibit HIV-1 replication

31 March 2020

1 reference

Dating the origin of the CCR5-Delta32 AIDS-resistance allele by the coalescence of haplotypes

31 March 2020

1 reference

Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection

31 March 2020

1 reference

Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene

31 March 2020

1 reference

C-C chemokines, pivotal in protection against HIV type 1 infection

31 March 2020

1 reference

Correlates of resistance to HIV-1 infection in homosexual men with high-risk sexual behaviour

31 March 2020

1 reference

Detection of elevated serum beta-chemokine levels in seronegative Chinese individuals exposed to human immunodeficiency virus type 1.

31 March 2020

1 reference

Elevated T cell counts and RANTES expression in the genital mucosa of HIV-1-resistant Kenyan commercial sex workers

31 March 2020

1 reference

HIV type 1 resistance in Kenyan sex workers is not associated with altered cellular susceptibility to HIV type 1 infection or enhanced beta-chemokine production

31 March 2020

1 reference

Characterization of high-risk HIV-1 seronegative hemophiliacs

31 March 2020

1 reference

No difference in in vitro susceptibility to HIV type 1 between high-risk HIV-negative Ethiopian commercial sex workers and low-risk control subjects.

31 March 2020

1 reference

The influence of CCL3L1 gene-containing segmental duplications on HIV-1/AIDS susceptibility

31 March 2020

1 reference

HIV-1-specific mucosal IgA in a cohort of HIV-1-resistant Kenyan sex workers

31 March 2020

1 reference

HIV-specific mucosal and cellular immunity in HIV-seronegative partners of HIV-seropositive individuals

31 March 2020

1 reference

Human immunodeficiency virus (HIV)-specific IgA and HIV neutralizing activity in the serum of exposed seronegative partners of HIV-seropositive persons

31 March 2020

1 reference

Epidemiologic and biologic characterization of a cohort of human immunodeficiency virus type 1 highly exposed, persistently seronegative female sex workers in northern Thailand. Chiang Mai HEPS Working Group

31 March 2020

1 reference

Constitutive expression of stromal derived factor-1 by mucosal epithelia and its role in HIV transmission and propagation.

31 March 2020

1 reference

Secretory leukocyte protease inhibitor (SLPI) concentrations in cervical mucus of women with normal menstrual cycle

31 March 2020

1 reference

Human immunodeficiency virus type 1 stimulates the expression and production of secretory leukocyte protease inhibitor (SLPI) in oral epithelial cells: a role for SLPI in innate mucosal immunity

31 March 2020

1 reference

Temporal and anatomic relationship between virus replication and cytokine gene expression after vaginal simian immunodeficiency virus infection.

31 March 2020

1 reference

Boost for vaginal microbicides against HIV.

31 March 2020

1 reference

Microbicides--evaluating multiple formulations of C31G.

31 March 2020

1 reference

A randomized Phase I vaginal safety study of three concentrations of C31G vs. Extra Strength Gynol II.

31 March 2020

1 reference

Safety and tolerability of BufferGel, a novel vaginal microbicide, in women in the United States

31 March 2020

1 reference

Clinical development of microbicides for the prevention of HIV infection

31 March 2020

1 reference

Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group

31 March 2020

1 reference

AIDS. Promote HIV chemoprophylaxis research, don't prevent it.

31 March 2020

1 reference

HIV-1 attachment: another look.

31 March 2020

1 reference

Heparan sulfate targets the HIV-1 envelope glycoprotein gp120 coreceptor binding site.

31 March 2020

1 reference

Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120

31 March 2020

1 reference

The mannose-specific plant lectins from Cymbidium hybrid and Epipactis helleborine and the (N-acetylglucosamine)n-specific plant lectin from Urtica dioica are potent and selective inhibitors of human immunodeficiency virus and cytomegalovirus replic

31 March 2020

1 reference

Correlation between carbohydrate structures on the envelope glycoprotein gp120 of.HIV-1 and HIV-2 and syncytium inhibition with lectins

31 March 2020

1 reference

Antibody domain exchange is an immunological solution to carbohydrate cluster recognition

31 March 2020

1 reference

Cyanovirin-N inhibits AIDS virus infections in vaginal transmission models

31 March 2020

1 reference

Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies

31 March 2020

1 reference

Resistance of human immunodeficiency virus type 1 to the high-mannose binding agents cyanovirin N and concanavalin A.

31 March 2020

1 reference

New targets for inhibitors of HIV-1 replication

31 March 2020

1 reference

Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120.

31 March 2020

1 reference

Structural flexibility and functional valence of CD4-IgG2 (PRO 542): potential for cross-linking human immunodeficiency virus type 1 envelope spikes

31 March 2020

1 reference

Blockade of attachment and fusion receptors inhibits HIV-1 infection of human cervical tissue

31 March 2020

1 reference

Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins

31 March 2020

1 reference

Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion

31 March 2020

1 reference

Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1

31 March 2020

1 reference

Resistance to enfuvirtide, the first HIV fusion inhibitor

31 March 2020

1 reference

Antiretroviral activity of the anti-CD4 monoclonal antibody TNX-355 in patients infected with HIV type 1.

31 March 2020

1 reference

Diversity of receptors binding HIV on dendritic cell subsets

31 March 2020

1 reference

DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells

31 March 2020

1 reference

Recruitment of HIV and its receptors to dendritic cell-T cell junctions

31 March 2020

1 reference

Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells

31 March 2020

1 reference

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

31 March 2020

1 reference

CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1

31 March 2020

1 reference

The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

31 March 2020

1 reference

The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates

31 March 2020

1 reference

Identification of a major co-receptor for primary isolates of HIV-1

31 March 2020

1 reference

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

31 March 2020

1 reference

HIV blocked by chemokine antagonist

31 March 2020

1 reference

Aminooxypentane addition to the chemokine macrophage inflammatory protein-1alpha P increases receptor affinities and HIV inhibition.

31 March 2020

1 reference

Human immunodeficiency virus type 1 entry inhibitors selected on living cells from a library of phage chemokines.

31 March 2020

1 reference

Medicinal chemistry applied to a synthetic protein: development of highly potent HIV entry inhibitors

31 March 2020

1 reference

Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist.

31 March 2020

1 reference

Engineering chemokines to develop optimized HIV inhibitors

31 March 2020

1 reference

Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: a novel inhibitory mechanism of HIV infectivity

31 March 2020

1 reference

Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5.

31 March 2020

1 reference

Potent, broad-spectrum inhibition of human immunodeficiency virus type 1 by the CCR5 monoclonal antibody PRO 140

31 March 2020

1 reference

A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity

31 March 2020

1 reference

Emerging drug targets for antiretroviral therapy

31 March 2020

1 reference

Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection.

31 March 2020

1 reference

The CCR5 receptor-based mechanism of action of 873140, a potent allosteric noncompetitive HIV entry inhibitor

31 March 2020

1 reference

Generation and properties of a human immunodeficiency virus type 1 isolate resistant to the small molecule CCR5 inhibitor, SCH-417690 (SCH-D).

31 March 2020

1 reference

HIV transmission: closing all the doors

31 March 2020

1 reference

Long-term, controlled release of the HIV microbicide TMC120 from silicone elastomer vaginal rings.

31 March 2020

1 reference

An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection

31 March 2020

1 reference

In vitro and in vivo: the story of nonoxynol 9.

31 March 2020

1 reference

Vaginal washing and increased risk of HIV-1 acquisition among African women: a 10-year prospective study

31 March 2020

1 reference

Effect of heterosexual intercourse on mucosal alloimmunisation and resistance to HIV-1 infection.

31 March 2020

1 reference

The Toll-like receptor 7 (TLR7) agonist, imiquimod, and the TLR9 agonist, CpG ODN, induce antiviral cytokines and chemokines but do not prevent vaginal transmission of simian immunodeficiency virus when applied intravaginally to rhesus macaques

31 March 2020

1 reference

Recommendations for the nonclinical development of topical microbicides for prevention of HIV transmission: an update

31 March 2020

1 reference

Microflora changes with the use of a vaginal microbicide.

31 March 2020

1 reference

Protection of macaques from vaginal SHIV challenge by an orally delivered CCR5 inhibitor

31 March 2020

1 reference

Candidate microbicides block HIV-1 infection of human immature Langerhans cells within epithelial tissue explants

31 March 2020

1 reference

Development of an in vitro organ culture model to study transmissionof HIV-1 in the female genital tract

31 March 2020

1 reference

Parameters of human immunodeficiency virus infection of human cervical tissue and inhibition by vaginal virucides

31 March 2020

1 reference

The nonnucleoside reverse transcriptase inhibitor UC-781 inhibits human immunodeficiency virus type 1 infection of human cervical tissue and dissemination by migratory cells

31 March 2020

1 reference

In vitro models of mucosal HIV transmission

31 March 2020

1 reference

Vaginal transmission of HIV-1 in hu-SCID mice: a new model for the evaluation of vaginal microbicides.

31 March 2020

1 reference

Vaginal transmission of cell-associated HIV-1 in the mouse is blocked by a topical, membrane-modifying agent

31 March 2020

1 reference

HIV-1 infection in a small animal human vaginal xenograft model

31 March 2020

1 reference

Effect of a cellulose acetate phthalate topical cream on vaginal transmission of simian immunodeficiency virus in rhesus monkeys

31 March 2020

1 reference

Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Enhanced inhibition of human immunodeficiency virus type 1 by Met-stromal-derived factor 1beta correlates with down-modulation of CXCR4.

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Differential inhibition of human immunodeficiency virus type 1 fusion, gp120 binding, and CC-chemokine activity by monoclonal antibodies to CCR5

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRI1848

1 reference

14 August 2017

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